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275 results

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Page 1
Substitution mutational signatures in whole-genome-sequenced cancers in the UK population.
Degasperi A, Zou X, Amarante TD, Martinez-Martinez A, Koh GCC, Dias JML, Heskin L, Chmelova L, Rinaldi G, Wang VYW, Nanda AS, Bernstein A, Momen SE, Young J, Perez-Gil D, Memari Y, Badja C, Shooter S, Czarnecki J, Brown MA, Davies HR; Genomics England Research Consortium; Nik-Zainal S. Degasperi A, et al. Among authors: koh gcc. Science. 2022 Apr 22;376(6591):science.abl9283. doi: 10.1126/science.abl9283. eCollection 2022 Apr 22. Science. 2022. PMID: 35949260 Free PMC article.
CoViD-19: una valutazione a distanza in medicina generale.
Greenhalgh T, Koh GCH, Car J. Greenhalgh T, et al. Among authors: koh gch. Recenti Prog Med. 2020 Apr;111(4):231-237. doi: 10.1701/3347.33186. Recenti Prog Med. 2020. PMID: 32319445 Italian. No abstract available.
Large-scale analysis of whole genome sequencing data from formalin-fixed paraffin-embedded cancer specimens demonstrates preservation of clinical utility.
Basyuni S, Heskin L, Degasperi A, Black D, Koh GCC, Chmelova L, Rinaldi G, Bell S, Grybowicz L, Elgar G, Memari Y, Robbe P, Kingsbury Z, Caldas C, Abraham J, Schuh A, Jones L; PARTNER Trial Group; Personalised Breast Cancer Program Group; Tischkowitz M, Brown MA, Davies HR, Nik-Zainal S. Basyuni S, et al. Among authors: koh gcc. Nat Commun. 2024 Sep 4;15(1):7731. doi: 10.1038/s41467-024-51577-2. Nat Commun. 2024. PMID: 39231944 Free PMC article.
A redefined InDel taxonomy provides insights into mutational signatures.
Koh GCC, Nanda AS, Rinaldi G, Boushaki S, Degasperi A, Badja C, Pregnall AM, Zhao SJ, Chmelova L, Black D, Heskin L, Dias J, Young J, Memari Y, Shooter S, Czarnecki J, Brown MA, Davies HR, Zou X, Nik-Zainal S. Koh GCC, et al. Nat Genet. 2025 May;57(5):1132-1141. doi: 10.1038/s41588-025-02152-y. Epub 2025 Apr 10. Nat Genet. 2025. PMID: 40210680 Free PMC article.
A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage.
Zou X, Koh GCC, Nanda AS, Degasperi A, Urgo K, Roumeliotis TI, Agu CA, Badja C, Momen S, Young J, Amarante TD, Side L, Brice G, Perez-Alonso V, Rueda D, Gomez C, Bushell W, Harris R, Choudhary JS; Genomics England Research Consortium; Jiricny J, Skarnes WC, Nik-Zainal S. Zou X, et al. Among authors: koh gcc. Nat Cancer. 2021 Jun;2(6):643-657. doi: 10.1038/s43018-021-00200-0. Epub 2021 Apr 26. Nat Cancer. 2021. PMID: 34164627 Free PMC article.
Proxy medical decision-making: national survey.
Phua AI, Zakaria C, Pakianathan PV, Chan N, Lim MJR, Liew TM, Koh GCH, Foong PS. Phua AI, et al. Among authors: koh gch. BMJ Support Palliat Care. 2024 Dec 14:spcare-2024-005179. doi: 10.1136/spcare-2024-005179. Online ahead of print. BMJ Support Palliat Care. 2024. PMID: 39638427
Insights from multi-omic modeling of neurodegeneration in xeroderma pigmentosum using an induced pluripotent stem cell system.
Badja C, Momen S, Koh GCC, Boushaki S, Roumeliotis TI, Kozik Z, Jones I, Bousgouni V, Dias JML, Krokidis MG, Young J, Chen H, Yang M, Docquier F, Memari Y, Valcarcel-Zimenez L, Gupta K, Kong LR, Fawcett H, Robert F, Zhao S, Degasperi A, Kumar Y, Davies H, Harris R, Frezza C, Chatgilialoglu C, Sarkany R, Lehmann A, Bakal C, Choudhary J, Fassihi H, Nik-Zainal S. Badja C, et al. Among authors: koh gcc. Cell Rep. 2024 Jun 25;43(6):114243. doi: 10.1016/j.celrep.2024.114243. Epub 2024 May 27. Cell Rep. 2024. PMID: 38805398 Free article.
Analyzing protein-protein interaction networks.
Koh GC, Porras P, Aranda B, Hermjakob H, Orchard SE. Koh GC, et al. J Proteome Res. 2012 Apr 6;11(4):2014-31. doi: 10.1021/pr201211w. Epub 2012 Mar 2. J Proteome Res. 2012. PMID: 22385417 Review.
275 results