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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1965 2
1966 2
1967 5
1968 5
1969 5
1970 4
1971 7
1972 6
1973 2
1974 4
1975 8
1976 4
1977 8
1978 5
1979 12
1980 10
1981 13
1982 15
1983 10
1984 10
1985 19
1986 18
1987 12
1988 23
1989 16
1990 15
1991 11
1992 23
1993 15
1994 54
1995 16
1996 30
1997 15
1998 11
1999 21
2000 21
2001 16
2002 12
2003 25
2004 14
2005 33
2006 25
2007 35
2008 37
2009 34
2010 38
2011 39
2012 34
2013 57
2014 43
2015 43
2016 38
2017 45
2018 55
2019 48
2020 75
2021 89
2022 79
2023 89
2024 89
2025 60

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Search Results

1,465 results

Results by year

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Page 1
TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A.
Ma XR, Prudencio M, Koike Y, Vatsavayai SC, Kim G, Harbinski F, Briner A, Rodriguez CM, Guo C, Akiyama T, Schmidt HB, Cummings BB, Wyatt DW, Kurylo K, Miller G, Mekhoubad S, Sallee N, Mekonnen G, Ganser L, Rubien JD, Jansen-West K, Cook CN, Pickles S, Oskarsson B, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Shorter J, Myong S, Green EM, Seeley WW, Petrucelli L, Gitler AD. Ma XR, et al. Among authors: koike y. Nature. 2022 Mar;603(7899):124-130. doi: 10.1038/s41586-022-04424-7. Epub 2022 Feb 23. Nature. 2022. PMID: 35197626 Free PMC article.
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang YJ, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Kargbo-Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Sacramento EK, Shah SI, Nalls MA, Colón-Mercado JM, Reyes JF, Ryan VH, Nelson MP, Cook CN, Li Z, Screven L, Kwan JY, Mehta PR, Zanovello M, Hallegger M, Shantaraman A, Ping L, Koike Y, Oskarsson B, Staff NP, Duong DM, Ahmed A, Secrier M, Ule J, Jacobson S, Reich DS, Rohrer JD, Malaspina A, Dickson DW, Glass JD, Ori A, Seyfried NT, Maragkakis M, Petrucelli L, Fratta P, Ward ME. Seddighi S, et al. Among authors: koike y. Sci Transl Med. 2024 Feb 14;16(734):eadg7162. doi: 10.1126/scitranslmed.adg7162. Epub 2024 Feb 14. Sci Transl Med. 2024. PMID: 38277467 Free PMC article.
Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome.
Rom O, Liu Y, Liu Z, Zhao Y, Wu J, Ghrayeb A, Villacorta L, Fan Y, Chang L, Wang L, Liu C, Yang D, Song J, Rech JC, Guo Y, Wang H, Zhao G, Liang W, Koike Y, Lu H, Koike T, Hayek T, Pennathur S, Xi C, Wen B, Sun D, Garcia-Barrio MT, Aviram M, Gottlieb E, Mor I, Liu W, Zhang J, Chen YE. Rom O, et al. Among authors: koike y. Sci Transl Med. 2020 Dec 2;12(572):eaaz2841. doi: 10.1126/scitranslmed.aaz2841. Sci Transl Med. 2020. PMID: 33268508 Free PMC article.
Population-specific putative causal variants shape quantitative traits.
Koyama S, Liu X, Koike Y, Hikino K, Koido M, Li W, Akaki K, Tomizuka K, Ito S, Otomo N, Suetsugu H, Yoshino S, Akiyama M, Saito K, Ishikawa Y, Benner C, Natarajan P, Ellinor PT, Mushiroda T, Horikoshi M, Ikeda M, Iwata N, Matsuda K; Biobank Japan Project; Niida S, Ozaki K, Momozawa Y, Ikegawa S, Takeuchi O, Ito K, Terao C. Koyama S, et al. Among authors: koike y. Nat Genet. 2024 Oct;56(10):2027-2035. doi: 10.1038/s41588-024-01913-5. Epub 2024 Oct 3. Nat Genet. 2024. PMID: 39363016 Free PMC article.
Genetic insights into ossification of the posterior longitudinal ligament of the spine.
Koike Y, Takahata M, Nakajima M, Otomo N, Suetsugu H, Liu X, Endo T, Imagama S, Kobayashi K, Kaito T, Kato S, Kawaguchi Y, Kanayama M, Sakai H, Tsuji T, Miyamoto T, Inose H, Yoshii T, Kashii M, Nakashima H, Ando K, Taniguchi Y, Takeuchi K, Ito S, Tomizuka K, Hikino K, Iwasaki Y, Kamatani Y, Maeda S, Nakajima H, Mori K, Seichi A, Fujibayashi S, Kanchiku T, Watanabe K, Tanaka T, Kida K, Kobayashi S, Takahashi M, Yamada K, Takuwa H, Lu HF, Niida S, Ozaki K, Momozawa Y; Genetic Study Group of Investigation Committee on Ossification of the Spinal Ligaments; Yamazaki M, Okawa A, Matsumoto M, Iwasaki N, Terao C, Ikegawa S. Koike Y, et al. Elife. 2023 Jul 18;12:e86514. doi: 10.7554/eLife.86514. Elife. 2023. PMID: 37461309 Free PMC article.
SETBP1 is dispensable for normal and malignant hematopoiesis.
Tanaka A, Nishimura K, Saika W, Kon A, Koike Y, Tatsumi H, Takeda J, Nomura M, Zang W, Nakayama M, Matsuda M, Yamazaki H, Fukumoto M, Ito H, Hayashi Y, Kitamura T, Kawamoto H, Takaori-Kondo A, Koseki H, Ogawa S, Inoue D. Tanaka A, et al. Among authors: koike y. Leukemia. 2023 Sep;37(9):1802-1811. doi: 10.1038/s41375-023-01970-5. Epub 2023 Jul 18. Leukemia. 2023. PMID: 37464069
Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia.
Tanaka A, Nakano TA, Nomura M, Yamazaki H, Bewersdorf JP, Mulet-Lazaro R, Hogg S, Liu B, Penson A, Yokoyama A, Zang W, Havermans M, Koizumi M, Hayashi Y, Cho H, Kanai A, Lee SC, Xiao M, Koike Y, Zhang Y, Fukumoto M, Aoyama Y, Konuma T, Kunimoto H, Inaba T, Nakajima H, Honda H, Kawamoto H, Delwel R, Abdel-Wahab O, Inoue D. Tanaka A, et al. Among authors: koike y. Blood. 2022 Aug 25;140(8):875-888. doi: 10.1182/blood.2021015325. Blood. 2022. PMID: 35709354 Free PMC article.
Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages.
Aoyama Y, Yamazaki H, Nishimura K, Nomura M, Shigehiro T, Suzuki T, Zang W, Tatara Y, Ito H, Hayashi Y, Koike Y, Fukumoto M, Tanaka A, Zhang Y, Saika W, Hasegawa C, Kasai S, Kong Y, Minakuchi Y, Itoh K, Yamamoto M, Toyokuni S, Toyoda A, Ikawa T, Takaori-Kondo A, Inoue D. Aoyama Y, et al. Among authors: koike y. Blood. 2025 Mar 13;145(11):1149-1163. doi: 10.1182/blood.2024025402. Blood. 2025. PMID: 39775457 Free PMC article.
GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region.
Ishikawa Y, Tanaka N, Asano Y, Kodera M, Shirai Y, Akahoshi M, Hasegawa M, Matsushita T, Saito K, Motegi SI, Yoshifuji H, Yoshizaki A, Kohmoto T, Takagi K, Oka A, Kanda M, Tanaka Y, Ito Y, Nakano K, Kasamatsu H, Utsunomiya A, Sekiguchi A, Niiro H, Jinnin M, Makino K, Makino T, Ihn H, Yamamoto M, Suzuki C, Takahashi H, Nishida E, Morita A, Yamamoto T, Fujimoto M, Kondo Y, Goto D, Sumida T, Ayuzawa N, Yanagida H, Horita T, Atsumi T, Endo H, Shima Y, Kumanogoh A, Hirata J, Otomo N, Suetsugu H, Koike Y, Tomizuka K, Yoshino S, Liu X, Ito S, Hikino K, Suzuki A, Momozawa Y, Ikegawa S, Tanaka Y, Ishikawa O, Takehara K, Torii T, Sato S, Okada Y, Mimori T, Matsuda F, Matsuda K, Amariuta T, Imoto I, Matsuo K, Kuwana M, Kawaguchi Y, Ohmura K, Terao C. Ishikawa Y, et al. Among authors: koike y. Nat Commun. 2024 Jan 31;15(1):319. doi: 10.1038/s41467-023-44541-z. Nat Commun. 2024. PMID: 38296975 Free PMC article.
1,465 results