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2015 1
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Page 1
Early symptom-associated inflammatory responses shift to type 2 responses in controlled human schistosome infection.
Houlder EL, Stam KA, Koopman JPR, König MH, Langenberg MCC, Hoogerwerf MA, Niewold P, Sonnet F, Janse JJ, Partal MC, Sijtsma JC, de Bes-Roeleveld LHM, Kruize YCM, Yazdanbakhsh M, Roestenberg M. Houlder EL, et al. Among authors: koopman jpr. Sci Immunol. 2024 Jul 5;9(97):eadl1965. doi: 10.1126/sciimmunol.adl1965. Epub 2024 Jul 5. Sci Immunol. 2024. PMID: 38968336
Safety and Efficacy of Immunization with a Late-Liver-Stage Attenuated Malaria Parasite.
Lamers OAC, Franke-Fayard BMD, Koopman JPR, Roozen GVT, Janse JJ, Chevalley-Maurel SC, Geurten FJA, de Bes-Roeleveld HM, Iliopoulou E, Colstrup E, Wessels E, van Gemert GJ, van de Vegte-Bolmer M, Graumans W, Stoter TR, Mordmüller BG, Houlder EL, Bousema T, Murugan R, McCall MBB, Janse CJ, Roestenberg M. Lamers OAC, et al. Among authors: koopman jpr. N Engl J Med. 2024 Nov 21;391(20):1913-1923. doi: 10.1056/NEJMoa2313892. N Engl J Med. 2024. PMID: 39565990 Clinical Trial.
Clinical tolerance but no protective efficacy in a placebo-controlled trial of repeated controlled schistosome infection.
Koopman JPR, Houlder EL, Janse JJ, Lamers OA, Roozen GV, Sijtsma JC, Casacuberta-Partal M, Hilt ST, van der Stoep MYEC, van Amerongen-Westra IM, Brienen EA, Wammes LJ, van Lieshout L, van Dam GJ, Corstjens PL, van Diepen A, Yazdanbakhsh M, Hokke CH, Roestenberg M. Koopman JPR, et al. J Clin Invest. 2024 Dec 12;135(4):e185422. doi: 10.1172/JCI185422. J Clin Invest. 2024. PMID: 39666392 Free PMC article. Clinical Trial.
T cell responses in repeated controlled human schistosome infection compared to natural exposure.
Driciru E, Koopman JPR, Steenbergen S, Sonnet F, Stam KA, Bes-Roeleveld L, Iliopoulou E, Janse JJ, Sijtsma J, Nambuya I, Hilt ST, König M, Kruize Y, Casacuberta-Partal M, Egesa M, van Dam GJ, Corstjens PLAM, van Lieshout L, Mpairwe H, MacDonald AS, Yazdanbakhsh M, Elliott AM, Roestenberg M, Houlder EL. Driciru E, et al. Among authors: koopman jpr. Nat Commun. 2025 Jul 24;16(1):6827. doi: 10.1038/s41467-025-62144-8. Nat Commun. 2025. PMID: 40707512 Free PMC article. Clinical Trial.
Single immunization with genetically attenuated Pf∆mei2 (GA2) parasites by mosquito bite in controlled human malaria infection: a placebo-controlled randomized trial.
Roozen GVT, van Schuijlenburg R, Hensen ADO, Koopman JPR, Lamers OAC, Geurten FJA, Sijtsma JC, Baalbergen E, Janse JJ, Chevalley-Maurel S, Naar CM, Bezemer S, Kroeze H, van de Stadt HJF, de Visser B, Meij P, Tihaya MS, Colstrup E, Iliopoulou E, de Bes-Roeleveld HM, Wessels E, van der Stoep MYEC, Janse CJ, Murugan R, Franke-Fayard BMD, Roestenberg M. Roozen GVT, et al. Among authors: koopman jpr. Nat Med. 2025 Jan;31(1):218-222. doi: 10.1038/s41591-024-03347-2. Epub 2025 Jan 3. Nat Med. 2025. PMID: 39753962 Free PMC article. Clinical Trial.
Pulmonary inflammation promoted by type-2 dendritic cells is a feature of human and murine schistosomiasis.
Houlder EL, Costain AH, Nambuya I, Brown SL, Koopman JPR, Langenberg MCC, Janse JJ, Hoogerwerf MA, Ridley AJL, Forde-Thomas JE, Colombo SAP, Winkel BMF, Galdon AA, Hoffmann KF, Cook PC, Roestenberg M, Mpairwe H, MacDonald AS. Houlder EL, et al. Among authors: koopman jpr. Nat Commun. 2023 Apr 3;14(1):1863. doi: 10.1038/s41467-023-37502-z. Nat Commun. 2023. PMID: 37012228 Free PMC article.
Uganda Schistosomiasis Symposium 2023: understanding morbidity drivers and developing controlled human infection models for vaccine research.
Egesa M, Kiberu D, Sanya RE, Alabi A, Sonnet F, Koopman JPR, Baluku JB, Oguttu DW, Driciru E, Odongo M, Walusimbi B, Elliott AM, Nkurunungi G. Egesa M, et al. Among authors: koopman jpr. Trends Parasitol. 2023 Jul;39(7):489-495. doi: 10.1016/j.pt.2023.03.017. Epub 2023 Apr 7. Trends Parasitol. 2023. PMID: 37032215 No abstract available.
Establishing a single-sex controlled human Schistosoma mansoni infection model for Uganda: protocol for safety and dose-finding trial.
Abaasa A, Egesa M, Driciru E, Koopman JPR, Kiyemba R, Sanya RE, Nassuuna J, Ssali A, Kimbugwe G, Wajja A, van Dam GJ, Corstjens PLAM, Cose S, Seeley J, Kamuya D, Webb EL, Yazdanbakhsh M, Kaleebu P, Siddiqui AA, Kabatereine N, Tukahebwa E, Roestenberg M, Elliott AM. Abaasa A, et al. Among authors: koopman jpr. Immunother Adv. 2023 Jul 20;3(1):ltad010. doi: 10.1093/immadv/ltad010. eCollection 2023. Immunother Adv. 2023. PMID: 37538934 Free PMC article.
30 results