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Unanswered questions in prostate cancer - findings of an international multi-stakeholder consensus by the PIONEER consortium.
Omar MI, MacLennan S, Ribal MJ, Roobol MJ, Dimitropoulos K, van den Broeck T, MacLennan SJ, Axelsson SE, Gandaglia G, Willemse PP, Mastris K, Ransohoff JB, Devecseri Z, Abbott T, De Meulder B, Bjartell A, Asiimwe A, N'Dow J; PIONEER Consortium. Omar MI, et al. Nat Rev Urol. 2023 Aug;20(8):494-501. doi: 10.1038/s41585-023-00748-9. Epub 2023 Apr 3. Nat Rev Urol. 2023. PMID: 37012441 Review.
PIONEER big data platform for prostate cancer: lessons for advancing future real-world evidence research.
Lawlor A, Beyer K, Russell B, Steinbeisser C, Bjartell A, De Meulder B, Omar MI, Hulsen T, Butler J, N'Dow J, Rivas JG, Gandaglia G, Nicoletti R, Sakalis V, Smith EJ, Maass M, Zong J, Fullwood L, Abbott T, Tafreshiha A, Papineni K, Snijder R, Horgan D, Seager S, Evans-Axelsson S, Ribal MJ, Roobol MJ, Van Hemelrijck M; PIONEER Consortium. Lawlor A, et al. Nat Rev Urol. 2025 Feb;22(2):116-124. doi: 10.1038/s41585-024-00925-4. Epub 2024 Sep 9. Nat Rev Urol. 2025. PMID: 39251785 Review.
How Well do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis.
Siltari A, Lönnerbro R, Pang K, Shiranov K, Asiimwe A, Evans-Axelsson S, Franks B, Kiran A, Murtola TJ, Schalken J, Steinbeisser C, Bjartell A, Auvinen A; PIONEER Consortium. Siltari A, et al. Clin Genitourin Cancer. 2023 Apr;21(2):316.e1-316.e11. doi: 10.1016/j.clgc.2022.09.006. Epub 2022 Sep 11. Clin Genitourin Cancer. 2023. PMID: 36243664 Free article.
Real-world Evidence on Baseline Characteristics and Treatment in Metastatic Hormone-sensitive Prostate Cancer: Findings from the PIONEER 2.0 Big Data Investigation Group.
Rivas JG, Kraft P, Evans-Axelsson S, Hijazy A, Beyer K, De Meulder B, Liu AQ, Golozar A, Harbachou A, Feng Q, Snijder R, Steinbeisser C, Remmers S, Gandaglia G, Rajwa P, Kotik D, Kasivisvanathan V, Omar MI, Sierra JM, Briganti A, Gacci M, Willemse PM, Brash JT, Davies E, Cornford P, Abbott T, N'Dow J, Nicoletti R; PIONEER 2.0 Big Data Investigation Group. Rivas JG, et al. Among authors: kotik d. Eur Urol Open Sci. 2025 Oct 7;81:82-91. doi: 10.1016/j.euros.2025.09.010. eCollection 2025 Nov. Eur Urol Open Sci. 2025. PMID: 41127821 Free PMC article.
Observational Health Data Analysis of the Cardiovascular Adverse Events of Systemic Treatment in Patients with Metastatic Hormone-sensitive Prostate Cancer: Big Data Analytics Using the PIONEER Platform.
Rajwa P, Borkowetz A, Abbott T, Alberti A, Beyer K, Bjartell A, Brash JT, Chilelli A, Davies E, Meulder B, Fazekas T, Golozar A, Hijazy A, Josefsson A, Kasivisvanathan V, Kolde R, Kotik D, Leapman MS, Miszczyk M, Nicoletti R, Prinsen P, Remmers S, Ribal MJ, Rivas JG, Rodriguez-Sanchez L, Roobol MJ, Smith E, Snijder R, Steinbeisser C, Stroomberg HV, Gandaglia G, Cornford P, Evans-Axelsson S, N'Dow J, Willemse PM; PIONEER Consortium. Rajwa P, et al. Among authors: kotik d. Eur Urol Focus. 2025 Nov;11(6):926-936. doi: 10.1016/j.euf.2025.08.005. Epub 2025 Oct 3. Eur Urol Focus. 2025. PMID: 41046191
The Key Role of Patient Involvement in the Development of Core Outcome Sets in Prostate Cancer.
Beyer K, MacLennan SJ, Moris L, Lardas M, Mastris K, Hooker G, Greene R, Briers E, Omar MI, Healey J, Tripathee S, Gandaglia G, Venderbos LDF, Smith EJ, Bjorkqvist J, Asiimwe A, Huber J, Roobol MJ, Zong J, Bjartell A, N'Dow J, Briganti A, MacLennan S, Van Hemelrijck M; PIONEER Consortium; EAU; LU; UNISR; Erasmus; UKE; TAU; KCL; EORTC; TTOP; ICHOM; ECPC; ASSOC EISBM; ICL; Hyve; EAPM; PM; WI; UoA; TUD; Fraunhofer; UGOT; Radboud; IHE; Bayer AG; SANOFI; ASTELLAS; SAS; Janssen; IQVIA; eGF-eCancer; AstraZeneca; HelmHoltz. Beyer K, et al. Eur Urol Focus. 2021 Sep;7(5):943-946. doi: 10.1016/j.euf.2021.09.008. Epub 2021 Oct 1. Eur Urol Focus. 2021. PMID: 34602368 Free article.
Research Protocol for an Observational Health Data Analysis on the Adverse Events of Systemic Treatment in Patients with Metastatic Hormone-sensitive Prostate Cancer: Big Data Analytics Using the PIONEER Platform.
Rajwa P, Borkowetz A, Abbott T, Alberti A, Bjartell A, Brash JT, Campi R, Chilelli A, Conover M, Constantinovici N, Davies E, De Meulder B, Eid S, Gacci M, Golozar A, Hafeez H, Haque S, Hijazy A, Hulsen T, Josefsson A, Khalid S, Kolde R, Kotik D, Kurki S, Lambrecht M, Leung CH, Moreno J, Nicoletti R, Nieboer D, Oja M, Palanisamy S, Prinsen P, Reich C, Raffaele Resta G, Ribal MJ, Gómez Rivas J, Smith E, Snijder R, Steinbeisser C, Vandenberghe F, Cornford P, Evans-Axelsson S, N'Dow J, Willemse PM. Rajwa P, et al. Among authors: kotik d. Eur Urol Open Sci. 2024 Mar 25;63:81-88. doi: 10.1016/j.euros.2024.02.019. eCollection 2024 May. Eur Urol Open Sci. 2024. PMID: 38572301 Free PMC article.