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Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.
J Exp Med. 1994 Dec 1;180(6):2049-58. doi: 10.1084/jem.180.6.2049.
J Exp Med. 1994.
PMID: 7964482
Free PMC article.
Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28.
Metzler WJ, Bajorath J, Fenderson W, Shaw SY, Constantine KL, Naemura J, Leytze G, Peach RJ, Lavoie TB, Mueller L, Linsley PS.
Metzler WJ, et al.
Nat Struct Biol. 1997 Jul;4(7):527-31. doi: 10.1038/nsb0797-527.
Nat Struct Biol. 1997.
PMID: 9228944
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