Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1995 Jul;6(7):459-63.
doi: 10.1007/BF00360654.

Genetic map of 16 polymorphic markers forming three linkage groups assigned to rat chromosome 4

E A Goldmuntz  1 , E F Remmers, Y Du, H Zha, P Mathern, L J Crofford, R L Wilder
Affiliations

Genetic map of 16 polymorphic markers forming three linkage groups assigned to rat chromosome 4

E A Goldmuntz et al. Mamm Genome. 1995 Jul.

Abstract

Sixteen polymorphic markers, including markers for eight new loci, forming three linkage groups, were assigned to rat Chromosome (Chr) 4 by linkage analysis of the progeny of an F2 intercross of Fischer (F344/N) and Lewis (LEW/N) inbred rats. One gene, Igk, was mapped by restriction fragment length polymorphism (RFLP) analysis. One marker for Tcrb was identified by the polymorphic insertion of a repetitive LINE element. The remaining 14 markers contained polymorphic simple sequence repeats (SSRs). Ten were identified in genes (Tgfa, Npy, Prss1, Prss2, Aldr1, Iapp, Prp, Eno2, Cacnl1a1, and Il6), one was identified in a sequence related to a gene (Egr4l1), and three were identified in anonymous DNA segments. The SSR markers were highly polymorphic in 16 inbred rat strains. These markers expand the genetic map of the rat and should be useful in future genetic studies of inbred rats.

PubMed Disclaimer

References

    1. Genomics. 1987 Oct;1(2):174-81 - PubMed
    1. Mamm Genome. 1993 Nov;4(11):670-5 - PubMed
    1. Mamm Genome. 1993;4(5):265-70 - PubMed
    1. Immunogenetics. 1992;35(5):324-31 - PubMed
    1. Nat Genet. 1995 Jan;9(1):63-9 - PubMed

LinkOut - more resources