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. 1994 Dec 15;150(2):341-4.
doi: 10.1016/0378-1119(94)90449-9.

Cloning of cDNAs coding for the G alpha i1 and G alpha i2 G-proteins from chick brain

E J Kilbourne  1 , J B Galper
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Cloning of cDNAs coding for the G alpha i1 and G alpha i2 G-proteins from chick brain

E J Kilbourne et al. Gene. .

Abstract

We have cloned and characterized several cDNAs coding for G-protein inhibitory alpha subunits (G alpha i) from a chick brain cDNA library. Based on homology to G alpha subunits from other eukaryotes, these clones were designated chick G alpha i1 and G alpha i2. On the deduced amino-acid level, G alpha i1 and G alpha i2 were found to be 98 and 95% identical to rat G alpha i1 and G alpha i2, respectively. Using RNase protection analysis, the G alpha i1 and G alpha i2 mRNAs were found to be expressed in chick atria, ventricle, lung, liver, brain and kidney.

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