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Page 1
Structure of the nutrient-sensing hub GATOR2.
Valenstein ML, Rogala KB, Lalgudi PV, Brignole EJ, Gu X, Saxton RA, Chantranupong L, Kolibius J, Quast JP, Sabatini DM. Valenstein ML, et al. Among authors: lalgudi pv. Nature. 2022 Jul;607(7919):610-616. doi: 10.1038/s41586-022-04939-z. Epub 2022 Jul 13. Nature. 2022. PMID: 35831510 Free PMC article.
Discovery and engineering of the antibody response to a prominent skin commensal.
Bousbaine D, Bauman KD, Chen YE, Lalgudi PV, Nguyen TTD, Swenson JM, Yu VK, Tsang E, Conlan S, Li DB, Jbara A, Zhao A, Naziripour A, Veinbachs A, Lee YE, Phung JL, Dimas A, Jain S, Meng X, Pham TPT, McLaughlin MI, Barkal LJ, Gribonika I, Van Rompay KKA, Kong HH, Segre JA, Belkaid Y, Barnes CO, Fischbach MA. Bousbaine D, et al. Among authors: lalgudi pv. Nature. 2025 Feb;638(8052):1054-1064. doi: 10.1038/s41586-024-08489-4. Epub 2024 Dec 11. Nature. 2025. PMID: 39662508 Free PMC article.
Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila.
Gu X, Jouandin P, Lalgudi PV, Binari R, Valenstein ML, Reid MA, Allen AE, Kamitaki N, Locasale JW, Perrimon N, Sabatini DM. Gu X, et al. Among authors: lalgudi pv. Nature. 2022 Aug;608(7921):209-216. doi: 10.1038/s41586-022-04960-2. Epub 2022 Jul 20. Nature. 2022. PMID: 35859173 Free PMC article.
Amino acids and KLHL22 do not activate mTORC1 via DEPDC5 degradation.
Valenstein ML, Lalgudi PV, Kedir JF, Condon KJ, Platzek A, Freund DG, Taylor MS, Xu Y, Chivukula RR, Sabatini DM. Valenstein ML, et al. Among authors: lalgudi pv. Nature. 2025 Jan;637(8045):E11-E14. doi: 10.1038/s41586-024-07974-0. Epub 2025 Jan 8. Nature. 2025. PMID: 39780017 No abstract available.
Structural basis for the dynamic regulation of mTORC1 by amino acids.
Valenstein ML, Wranik M, Lalgudi PV, Linde-Garelli KY, Choi Y, Chivukula RR, Sabatini DM, Rogala KB. Valenstein ML, et al. Among authors: lalgudi pv. Nature. 2025 Oct;646(8084):493-500. doi: 10.1038/s41586-025-09428-7. Epub 2025 Aug 20. Nature. 2025. PMID: 40836086 Free PMC article.
Discovery and engineering of the antibody response against a prominent skin commensal.
Bousbaine D, Bauman KD, Chen YE, Yu VK, Lalgudi PV, Naziripour A, Veinbachs A, Phung JL, Nguyen TTD, Swenson JM, Lee YE, Dimas A, Jain S, Meng X, Pham TPT, Zhao A, Barkal L, Gribonika I, Van Rompay KKA, Belkaid Y, Barnes CO, Fischbach MA. Bousbaine D, et al. Among authors: lalgudi pv. bioRxiv [Preprint]. 2024 Jan 23:2024.01.23.576900. doi: 10.1101/2024.01.23.576900. bioRxiv. 2024. Update in: Nature. 2025 Feb;638(8052):1054-1064. doi: 10.1038/s41586-024-08489-4. PMID: 38328052 Free PMC article. Updated. Preprint.
A molecular cell atlas of mouse lemur, an emerging model primate.
Tabula Microcebus Consortium; Ezran C, Liu S, Chang S, Ming J, Botvinnik O, Penland L, Tarashansky A, de Morree A, Travaglini KJ, Zhao J, Wang G, Hasegawa K, Sin H, Sit R, Okamoto J, Sinha R, Zhang Y, Karanewsky CJ, Pendleton JL, Morri M, Perret M, Aujard F, Stryer L, Artandi S, Fuller MT, Weissman IL, Rando TA, Ferrell JE Jr, Wang B, De Vlaminck I, Yang C, Casey KM, Albertelli MA, Pisco AO, Karkanias J, Neff N, Wu AR, Quake SR, Krasnow MA. Tabula Microcebus Consortium, et al. Nature. 2025 Aug;644(8075):173-184. doi: 10.1038/s41586-025-09113-9. Epub 2025 Jul 30. Nature. 2025. PMID: 40739356 Free PMC article.
Mouse lemur cell atlas informs primate genes, physiology and disease.
Ezran C, Liu S, Chang S, Ming J, Guethlein LA, Wang MFZ, Dehghannasiri R, Olivieri J, Frank HK, Tarashansky A, Koh W, Jing Q, Botvinnik O, Antony J; Tabula Microcebus Consortium; Pisco AO, Karkanias J, Yang C, Ferrell JE Jr, Boyd SD, Parham P, Long JZ, Wang B, Salzman J, De Vlaminck I, Wu AR, Quake SR, Krasnow MA. Ezran C, et al. Nature. 2025 Aug;644(8075):185-196. doi: 10.1038/s41586-025-09114-8. Epub 2025 Jul 30. Nature. 2025. PMID: 40739355 Free PMC article.
11 results