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Page 1
Showing results for lambda c
Search for Lampada C instead (3 results)
What Have We Learned from Studies of IFN-lambda Variants and Hepatitis C Virus Infection?
O'Brien TR, Jackson SS. O'Brien TR, et al. J Interferon Cytokine Res. 2019 Oct;39(10):618-626. doi: 10.1089/jir.2019.0048. Epub 2019 Jun 4. J Interferon Cytokine Res. 2019. PMID: 31161939 Free PMC article. Review.
Chronic infection with the hepatitis C virus (HCV) is a major cause of cirrhosis and hepatocellular carcinoma. In 2009, genome-wide association studies (GWAS) strongly linked genetic variants in the interferon lambda (IFN-lambda) chromosomal region to HCV cle …
Chronic infection with the hepatitis C virus (HCV) is a major cause of cirrhosis and hepatocellular carcinoma. In 2009, genome-wide a …
Interferon-lambda and therapy for chronic hepatitis C virus infection.
Donnelly RP, Dickensheets H, O'Brien TR. Donnelly RP, et al. Trends Immunol. 2011 Sep;32(9):443-50. doi: 10.1016/j.it.2011.07.002. Epub 2011 Aug 5. Trends Immunol. 2011. PMID: 21820962 Free PMC article. Review.
Interferon (IFN)-alpha, a type-I IFN, is widely used to treat chronic hepatitis C virus infection, but the broad expression of IFN-alpha receptors often leads to adverse reactions in many organs. Here, we examine IFN-lambda, a type-III IFN, as a therapeutic alternat …
Interferon (IFN)-alpha, a type-I IFN, is widely used to treat chronic hepatitis C virus infection, but the broad expression of IFN-al …
The Role of Interferon-lambda Locus Polymorphisms in Hepatitis C and Other Infectious Diseases.
Griffiths SJ, Dunnigan CM, Russell CD, Haas JG. Griffiths SJ, et al. J Innate Immun. 2015;7(3):231-42. doi: 10.1159/000369902. Epub 2015 Jan 23. J Innate Immun. 2015. PMID: 25634147 Free PMC article. Review.
Since its discovery in 2003, the type III interferon-lambda (IFN-lambda) family has been found to contribute significantly to the host response to infection. ...Several such GWAS have highlighted the IFN-lambda locus on chromosome 19q13 as an area of genetic …
Since its discovery in 2003, the type III interferon-lambda (IFN-lambda) family has been found to contribute significantly to …
Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes.
Chaturvedi N, Svarovskaia ES, Mo H, Osinusi AO, Brainard DM, Subramanian GM, McHutchison JG, Zeuzem S, Fellay J. Chaturvedi N, et al. Elife. 2019 Sep 3;8:e42542. doi: 10.7554/eLife.42542. Elife. 2019. PMID: 31478832 Free PMC article.
Genetic polymorphism in the interferon lambda (IFN-lambda) region is associated with spontaneous clearance of hepatitis C virus (HCV) infection and response to interferon-based treatment. ...We also assessed the combined impact of human and HCV variation on p …
Genetic polymorphism in the interferon lambda (IFN-lambda) region is associated with spontaneous clearance of hepatitis C …
Interferon-lambda in the immune response to hepatitis B virus and hepatitis C virus.
Pagliaccetti NE, Robek MD. Pagliaccetti NE, et al. J Interferon Cytokine Res. 2010 Aug;30(8):585-90. doi: 10.1089/jir.2010.0060. J Interferon Cytokine Res. 2010. PMID: 20645875 Free PMC article. Review.
Approximately 500 million people worldwide are chronically infected with the hepatitis B virus (HBV) or hepatitis C virus (HCV), and are therefore at an increased risk for developing fatal liver diseases such as cirrhosis and hepatocellular carcinoma. The intracellular ant …
Approximately 500 million people worldwide are chronically infected with the hepatitis B virus (HBV) or hepatitis C virus (HCV), and …
Interferon-alfa, interferon-lambda and hepatitis C.
O'Brien TR. O'Brien TR. Nat Genet. 2009 Oct;41(10):1048-50. doi: 10.1038/ng.453. Epub 2009 Sep 13. Nat Genet. 2009. PMID: 19749756 Free PMC article.
Three new studies report genetic variants near IL28B, which encodes interferon-lambda3 (interleukin 28B), are associated with response to treatment of chronic hepatitis C virus infection with interferon-alfa/ribavirin combination therapy. This renews interest in how interf …
Three new studies report genetic variants near IL28B, which encodes interferon-lambda3 (interleukin 28B), are associated with response to tr …
The c-myc protein represses the lambda 5 and TdT initiators.
Mai S, Mårtensson IL. Mai S, et al. Nucleic Acids Res. 1995 Jan 11;23(1):1-9. doi: 10.1093/nar/23.1.1. Nucleic Acids Res. 1995. PMID: 7870572 Free PMC article.
Two lambda 5 promoter-derived oligonucleotides (Inr lambda 5:1 and Inr lambda 5:2), each with a transcription start site, could promote transcription in transient transfection assays. ...The B' complexes of Inr lambda 5:1 and Inr lambda 5:2 each …
Two lambda 5 promoter-derived oligonucleotides (Inr lambda 5:1 and Inr lambda 5:2), each with a transcription start sit …
Interferon-lambda serum levels in hepatitis C.
Langhans B, Kupfer B, Braunschweiger I, Arndt S, Schulte W, Nischalke HD, Nattermann J, Oldenburg J, Sauerbruch T, Spengler U. Langhans B, et al. J Hepatol. 2011 May;54(5):859-65. doi: 10.1016/j.jhep.2010.08.020. Epub 2010 Oct 23. J Hepatol. 2011. PMID: 21145813
Carriers of the rs12979860 C allele associated with resolution of HCV infection exhibited increased IFN-lambda levels. Moreover, high IFN-lambda levels predisposed to spontaneous resolution of HCV infection. Thus, IFN-lambdas seem to play an important …
Carriers of the rs12979860 C allele associated with resolution of HCV infection exhibited increased IFN-lambda levels. Moreove …
Atypical Protein Kinase C lambda/iota Expression Is Associated with Malignancy of Oral Squamous Cell Carcinoma.
Baba J, Kioi M, Akimoto K, Nagashima Y, Taguri M, Inayama Y, Aoki I, Ohno S, Mitsudo K, Tohnai I. Baba J, et al. Anticancer Res. 2018 Nov;38(11):6291-6297. doi: 10.21873/anticanres.12985. Anticancer Res. 2018. PMID: 30396949
BACKGROUND/AIM: Atypical protein kinase C lambda/iota (aPKClambda/iota) is a cell polarity-regulator localized in the tight junction and apical membrane in epithelial cells. ...
BACKGROUND/AIM: Atypical protein kinase C lambda/iota (aPKClambda/iota) is a cell polarity-regulator localized in the tight ju …
3,790 results