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1965 1
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61 results

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Page 1
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.
Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, Bala E, Lee KE, Hunter DJ, Sardell RJ, Mitchell P, Merriam JE, Cipriani V, Hoffman JD, Schick T, Lechanteur YT, Guymer RH, Johnson MP, Jiang Y, Stanton CM, Buitendijk GH, Zhan X, Kwong AM, Boleda A, Brooks M, Gieser L, Ratnapriya R, Branham KE, Foerster JR, Heckenlively JR, Othman MI, Vote BJ, Liang HH, Souzeau E, McAllister IL, Isaacs T, Hall J, Lake S, Mackey DA, Constable IJ, Craig JE, Kitchner TE, Yang Z, Su Z, Luo H, Chen D, Ouyang H, Flagg K, Lin D, Mao G, Ferreyra H, Stark K, von Strachwitz CN, Wolf A, Brandl C, Rudolph G, Olden M, Morrison MA, Morgan DJ, Schu M, Ahn J, Silvestri G, Tsironi EE, Park KH, Farrer LA, Orlin A, Brucker A, Li M, Curcio CA, Mohand-Saïd S, Sahel JA, Audo I, Benchaboune M, Cree AJ, Rennie CA, Goverdhan SV, Grunin M, Hagbi-Levi S, Campochiaro P, Katsanis N, Holz FG, Blond F, Blanché H, Deleuze JF, Igo RP Jr, Truitt B, Peachey NS, Meuer SM, Myers CE, Moore EL, Klein R, Hauser MA, Postel EA, Courtenay MD, Schwartz SG, Kovach JL, Scott WK, Liew G, Tan AG, Gopinath B, Merriam JC, Smith RT, Khan JC,… See abstract for full author list ➔ Fritsche LG, et al. Among authors: laux r. Nat Genet. 2016 Feb;48(2):134-43. doi: 10.1038/ng.3448. Epub 2015 Dec 21. Nat Genet. 2016. PMID: 26691988 Free PMC article.
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
Baigent C, Landray MJ, Reith C, Emberson J, Wheeler DC, Tomson C, Wanner C, Krane V, Cass A, Craig J, Neal B, Jiang L, Hooi LS, Levin A, Agodoa L, Gaziano M, Kasiske B, Walker R, Massy ZA, Feldt-Rasmussen B, Krairittichai U, Ophascharoensuk V, Fellström B, Holdaas H, Tesar V, Wiecek A, Grobbee D, de Zeeuw D, Grönhagen-Riska C, Dasgupta T, Lewis D, Herrington W, Mafham M, Majoni W, Wallendszus K, Grimm R, Pedersen T, Tobert J, Armitage J, Baxter A, Bray C, Chen Y, Chen Z, Hill M, Knott C, Parish S, Simpson D, Sleight P, Young A, Collins R; SHARP Investigators. Baigent C, et al. Lancet. 2011 Jun 25;377(9784):2181-92. doi: 10.1016/S0140-6736(11)60739-3. Epub 2011 Jun 12. Lancet. 2011. PMID: 21663949 Free PMC article. Clinical Trial.
Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries.
Gorman BR, Voloudakis G, Igo RP Jr, Kinzy T, Halladay CW, Bigdeli TB, Zeng B, Venkatesh S, Cooke Bailey JN, Crawford DC, Markianos K, Dong F, Schreiner PA, Zhang W; VA Million Veteran Program; International AMD Genomics Consortium (IAMDGC); Hadi T, Anger MD, Stockwell A, Melles RB, Yin J, Choquet H, Kaye R, Patasova K, Patel PJ, Yaspan BL, Jorgenson E, Hysi PG, Lotery AJ, Gaziano JM, Tsao PS, Fliesler SJ, Sullivan JM, Greenberg PB, Wu WC, Assimes TL, Pyarajan S, Roussos P, Peachey NS, Iyengar SK. Gorman BR, et al. Nat Genet. 2024 Dec;56(12):2659-2671. doi: 10.1038/s41588-024-01764-0. Epub 2024 Dec 2. Nat Genet. 2024. PMID: 39623103
Alzheimer's disease plasma biomarkers in the Midwestern Amish.
Wang P, Song YE, Lynn A, Miskimen K, Gulyayev A, Prough MB, Dorfsman DA, Laux RA, Fuzzell SL, Hochstetler SD, Zaman AF, Adams LD, Caywood LJ, Clouse JE, Herington SD, Whitehead P, Liu Y, Moore N, Ogrocki P, Lerner AJ, Griswold AJ, Vance JM, Cuccaro ML, Scott WK, Pericak-Vance MA, Haines JL. Wang P, et al. Among authors: laux ra. Alzheimers Dement. 2025 Jun;21(6):e70328. doi: 10.1002/alz.70328. Alzheimers Dement. 2025. PMID: 40465679 Free PMC article.
The GGLEAM Study: Understanding Glaucoma in the Ohio Amish.
Waksmunski AR, Song YE, Kinzy TG, Laux RA, Sewell J, Fuzzell D, Fuzzell S, Miller S, Wiggs JL, Pasquale LR, Skarie JM, Haines JL, Cooke Bailey JN. Waksmunski AR, et al. Among authors: laux ra. Int J Environ Res Public Health. 2021 Feb 6;18(4):1551. doi: 10.3390/ijerph18041551. Int J Environ Res Public Health. 2021. PMID: 33561996 Free PMC article.
ABCA7 deletion lowers age at onset of Alzheimer's disease and interacts with APOE ε4 synergistically in African-ancestry populations.
Akgun B, Gulyayev AV, Coker M, Hamilton-Nelson KL, Olalusi O, Adams LD, Akinwande K, Whitehead PG, Diala S, Ogunronbi M, Laux RA, Akpalu A, Starks TD, Sarfo FS, Chavez J, Lwere K, Beecham GW, Akinyemi JO, Obiako R, Ndetei D, Caban-Holt A, Ayele B, Ogrocki P, Griswold AJ, Zaman AF, Mena PR, Martinez IM, Blanton SH, Okubadejo N, Damasceno A, Kalaria R, Cuccaro ML, McInerney KF; African Dementia Consortium (AfDC); Alzheimer's Disease Sequencing Project (ADSP); Bush WS, Kunkle BW, Ogunniyi A, Vance JM, Akinyemi RO, Haines JL, Reitz C, Byrd GS, Rajabli F, Pericak-Vance MA. Akgun B, et al. Among authors: laux ra. Alzheimers Dement. 2025 Aug;21(8):e70583. doi: 10.1002/alz.70583. Alzheimers Dement. 2025. PMID: 40832784 Free PMC article.
Psychometric approaches to defining cognitive phenotypes in the Old Order Amish.
Zaman A, Caywood L, Prough M, Clouse J, Harrington S, Adams L, Fuzzell D, Fuzzell S, Laux R, Hochstetler SD, Ogrocki P, Lerner A, Vance JM, Haines JL, Scott WK, Pericak-Vance MA, Cuccaro ML. Zaman A, et al. Among authors: laux r. Int J Geriatr Psychiatry. 2023 Apr;38(4):e5903. doi: 10.1002/gps.5903. Int J Geriatr Psychiatry. 2023. PMID: 36929524 Free PMC article.
Heritability of Choroidal Thickness in the Amish.
Sardell RJ, Nittala MG, Adams LD, Laux RA, Cooke Bailey JN, Fuzzell D, Fuzzell S, Reinhart-Mercer L, Caywood LJ, Horst V, Mackay T, Dana D, Sadda SR, Scott WK, Stambolian D, Haines JL, Pericak-Vance MA. Sardell RJ, et al. Among authors: laux ra. Ophthalmology. 2016 Dec;123(12):2537-2544. doi: 10.1016/j.ophtha.2016.09.001. Epub 2016 Oct 19. Ophthalmology. 2016. PMID: 27771146 Free PMC article.
Neuropsychiatric features in a multi-ethnic population with Alzheimer disease and mild cognitive impairment.
Celis K, Zaman A, Adams LD, Gardner O, Farid R, Starks TD, Lacroix FC, Hamilton-Nelson K, Mena P, Tejada S, Laux R, Song YE, Caban-Holt A, Feliciano-Astacio B, Vance JM, Haines JL, Byrd GS, Beecham GW, Pericak-Vance MA, Cuccaro ML. Celis K, et al. Among authors: laux r. Int J Geriatr Psychiatry. 2023 Sep;38(9):e5992. doi: 10.1002/gps.5992. Int J Geriatr Psychiatry. 2023. PMID: 37655494 Free PMC article.
61 results