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Page 1
Showing results for late n
Search for Layte N instead (1 results)
Late-Stage Alkylation of Heterocycles Using N-(Acyloxy)phthalimides.
Parida SK, Hota SK, Kumar R, Murarka S. Parida SK, et al. Chem Asian J. 2021 Apr 19;16(8):879-889. doi: 10.1002/asia.202100151. Epub 2021 Mar 16. Chem Asian J. 2021. PMID: 33662188 Review.
Synthetic methods enabling late-stage modification of heterocycles hold tremendous importance in the pharmaceutical and agrochemical industry and drug discovery. Accordingly, efficient, functional group tolerant and selective late-stage alkylation of valuable molecu …
Synthetic methods enabling late-stage modification of heterocycles hold tremendous importance in the pharmaceutical and agrochemical …
Late-Onset Immune-Related Adverse Events After Immune Checkpoint Inhibitor Therapy.
Durbin SM, Zubiri L, Perlman K, Wu CY, Lim T, Grealish K, Hathaway N, LoPiccolo J, Wang M, Falade A, Molina G, Jacoby TV, Shah N, Mooradian MJ, Reynolds KL. Durbin SM, et al. JAMA Netw Open. 2025 Mar 3;8(3):e252668. doi: 10.1001/jamanetworkopen.2025.2668. JAMA Netw Open. 2025. PMID: 40146104 Free PMC article.
OBJECTIVES: To assess the incidence of persistent or de novo late-onset irAEs requiring hospitalization and identify patient factors associated with risk of late-onset irAEs. ...In univariate analysis, ICI type was significantly associated with the timing of hospita …
OBJECTIVES: To assess the incidence of persistent or de novo late-onset irAEs requiring hospitalization and identify patient factors …
Azapeptide Atropisomers From Late-Stage N-Alkylations.
Helton ME, Howard CS, Prieto Bruno K, Cartrette KD, Bowles MO, Hearne WA, Proulx C. Helton ME, et al. J Org Chem. 2025 Jul 11;90(27):9549-9558. doi: 10.1021/acs.joc.5c01024. Epub 2025 Jun 30. J Org Chem. 2025. PMID: 40587606
We evaluate peptide sequence compatibility during late-stage azapeptide N-alkylation reactions and describe the atropisomeric properties of the azapeptoid and N1,N2-dialkylated azapeptide products. Our findings indicate that almost all protected amino acid side chai …
We evaluate peptide sequence compatibility during late-stage azapeptide N-alkylation reactions and describe the atropisomeric …
Reporting of late-onset immune-related adverse events with immune checkpoint inhibitors in VigiBase.
Noseda R, Bedussi F, Giunchi V, Fusaroli M, Raschi E, Ceschi A. Noseda R, et al. J Immunother Cancer. 2024 Nov 3;12(11):e009902. doi: 10.1136/jitc-2024-009902. J Immunother Cancer. 2024. PMID: 39489542 Free PMC article.
METHODS: Observational study comparing deduplicated ICSRs with ICIs reporting late-onset irAEs (occurred >90 days after ICI discontinuation) versus ICSRs with ICIs not reporting late-onset irAEs, collected in VigiBase from 2011 to December 31, 2022. ...Of these, …
METHODS: Observational study comparing deduplicated ICSRs with ICIs reporting late-onset irAEs (occurred >90 days after ICI discon …
Recent Advances in Transition-Metal-Free Late-Stage C-H and N-H Arylation of Heteroarenes Using Diaryliodonium Salts.
Besson T, Fruit C. Besson T, et al. Pharmaceuticals (Basel). 2021 Jul 11;14(7):661. doi: 10.3390/ph14070661. Pharmaceuticals (Basel). 2021. PMID: 34358087 Free PMC article. Review.
Transition-metal-free direct arylation of C-H or N-H bonds is one of the key emerging methodologies that is currently attracting tremendous attention. ...In this review, we emphasize the recent synthetic advances of late-stage C(sp2)-N and C(sp2)-C(sp2) bond- …
Transition-metal-free direct arylation of C-H or N-H bonds is one of the key emerging methodologies that is currently attracting trem …
Increasing the coverage of the N-terminome with LysN amino terminal enrichment (LATE).
Hanna R, Rozenberg A, Lavy T, Kleifeld O. Hanna R, et al. Methods Enzymol. 2023;686:1-28. doi: 10.1016/bs.mie.2023.04.003. Epub 2023 May 18. Methods Enzymol. 2023. PMID: 37532396
Negative selection N-terminomics enables the identification of free and naturally modified protein N-termini. Here, we present a streamlined protocol that combines two negative selection N-terminomics methods, LATE and HYTANE, to increase N-term …
Negative selection N-terminomics enables the identification of free and naturally modified protein N-termini. Here, we present …
Light-Powered Late-Stage Alkylation of N-Heteroaromatics in Flow.
Wang S, Zuo Z. Wang S, et al. ACS Cent Sci. 2025 Jun 5;11(6):826-827. doi: 10.1021/acscentsci.5c00926. eCollection 2025 Jun 25. ACS Cent Sci. 2025. PMID: 40606008 Free PMC article.
Continuous-flow photochemistry allows late-stage functionalization of N-heteroaromatics with gaseous alkane....
Continuous-flow photochemistry allows late-stage functionalization of N-heteroaromatics with gaseous alkane....
Late Neogene Lophophaenidae (Nassellaria, Radiolaria) from the eastern equatorial Pacific.
Trubovitz S, Renaudie J, Lazarus D, Noble P. Trubovitz S, et al. Zootaxa. 2022 Jul 4;5160(1):1-158. doi: 10.11646/zootaxa.5160.1.1. Zootaxa. 2022. PMID: 36095528 Review.
We discuss existing lophophaenid genera Amphiplecta Haeckel 1881, Arachnocorallium Haeckel 1887, Arachnocorys Haeckel 1860, Botryopera Haeckel 1887, Ceratocyrtis Btschli 1882, Lithomelissa Ehrenberg 1847, Lophophaena Ehrenberg 1847, and Peromelissa Haeckel 1881, including full sp …
We discuss existing lophophaenid genera Amphiplecta Haeckel 1881, Arachnocorallium Haeckel 1887, Arachnocorys Haeckel 1860, Botryopera Haeck …
Late benign biliary complications after pancreatoduodenectomy.
Ito T, Sugiura T, Okamura Y, Yamamoto Y, Ashida R, Aramaki T, Endo M, Matsubayashi H, Ishiwatari H, Uesaka K. Ito T, et al. Surgery. 2018 Jun;163(6):1295-1300. doi: 10.1016/j.surg.2018.02.015. Epub 2018 Apr 21. Surgery. 2018. PMID: 29685633
Perioperative variables were collected to analyze the risk factors for late biliary complications. The treatment of late biliary complications was then evaluated. RESULTS: A total of 28 patients (3.8%) developed late biliary complications with a median interv …
Perioperative variables were collected to analyze the risk factors for late biliary complications. The treatment of late bilia …
Oral Hygiene Study in Late Adolescence.
Mociu M, Bartok-Nicolae C, Raftu G, Briceag R, Caraiane A. Mociu M, et al. Curr Health Sci J. 2024 Apr-Jun;50(2):267-273. doi: 10.12865/CHSJ.50.02.12. Epub 2024 Jun 30. Curr Health Sci J. 2024. PMID: 39371057 Free PMC article.
The objective of this study is to determine prevalent behaviors and knowledge of oral hygiene on the late adolescents. Only individuals in the late stage of adolescence, specifically between the ages of 18 and 24, that were students from the "Ovidius" University of …
The objective of this study is to determine prevalent behaviors and knowledge of oral hygiene on the late adolescents. Only individua …
89,890 results
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