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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1969 3
1970 1
1972 1
1975 2
1979 1
1984 2
1985 1
1991 1
1992 4
1993 1
1994 3
1995 2
1997 1
1998 1
2000 1
2001 2
2003 1
2005 1
2006 1
2008 1
2013 1
2014 1
2016 2
2017 4
2018 2
2019 4
2020 3
2021 9
2022 11
2023 5
2024 11
2025 10

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88 results

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Page 1
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.
Gallo D, Young JTF, Fourtounis J, Martino G, Álvarez-Quilón A, Bernier C, Duffy NM, Papp R, Roulston A, Stocco R, Szychowski J, Veloso A, Alam H, Baruah PS, Fortin AB, Bowlan J, Chaudhary N, Desjardins J, Dietrich E, Fournier S, Fugère-Desjardins C, Goullet de Rugy T, Leclaire ME, Liu B, Bhaskaran V, Mamane Y, Melo H, Nicolas O, Singhania A, Szilard RK, Tkáč J, Yin SY, Morris SJ, Zinda M, Marshall CG, Durocher D. Gallo D, et al. Among authors: leclaire me. Nature. 2022 Apr;604(7907):749-756. doi: 10.1038/s41586-022-04638-9. Epub 2022 Apr 20. Nature. 2022. PMID: 35444283 Free PMC article.
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.
Szychowski J, Papp R, Dietrich E, Liu B, Vallée F, Leclaire ME, Fourtounis J, Martino G, Perryman AL, Pau V, Yin SY, Mader P, Roulston A, Truchon JF, Marshall CG, Diallo M, Duffy NM, Stocco R, Godbout C, Bonneau-Fortin A, Kryczka R, Bhaskaran V, Mao D, Orlicky S, Beaulieu P, Turcotte P, Kurinov I, Sicheri F, Mamane Y, Gallant M, Black WC. Szychowski J, et al. Among authors: leclaire me. J Med Chem. 2022 Aug 11;65(15):10251-10284. doi: 10.1021/acs.jmedchem.2c00552. Epub 2022 Jul 26. J Med Chem. 2022. PMID: 35880755 Free PMC article.
Lipofuscin-dependent stimulation of microglial cells.
Leclaire MD, Nettels-Hackert G, König J, Höhn A, Grune T, Uhlig CE, Hansen U, Eter N, Heiduschka P. Leclaire MD, et al. Graefes Arch Clin Exp Ophthalmol. 2019 May;257(5):931-952. doi: 10.1007/s00417-019-04253-x. Epub 2019 Jan 28. Graefes Arch Clin Exp Ophthalmol. 2019. PMID: 30693383
Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor.
Vallée F, Casás-Selves M, Bubenik M, Duplessis M, Sow B, Suarez C, Sangiorgi B, Li L, Hyer M, Papp R, Leclaire ME, Perryman AL, Liu B, Surprenant S, Mochirian P, Pau V, Maderova Z, Mader P, Yin SY, Goodfellow E, Roulston A, Stocco R, Godbout C, Baruah P, Bonneau-Fortin A, Schonhoft JD, Nejad P, Norman D, Truong VL, Crane S, Attia MA, Mao D, Sicheri F, Marshall CG, Zimmermann M, Bendahan D, Gallant M, Black WC. Vallée F, et al. Among authors: leclaire me. J Med Chem. 2025 Jun 12;68(11):10631-10647. doi: 10.1021/acs.jmedchem.5c00529. Epub 2025 May 16. J Med Chem. 2025. PMID: 40378279 Clinical Trial.
Allergies - A T cells perspective in the era beyond the TH1/TH2 paradigm.
Berker M, Frank LJ, Geßner AL, Grassl N, Holtermann AV, Höppner S, Kraef C, Leclaire MD, Maier P, Messerer DA, Möhrmann L, Nieke JP, Schoch D, Soll D, Woopen CM. Berker M, et al. Among authors: leclaire md. Clin Immunol. 2017 Jan;174:73-83. doi: 10.1016/j.clim.2016.11.001. Epub 2016 Nov 12. Clin Immunol. 2017. PMID: 27847316 Review.
[Geometric phagedenism].
Bombart, Huriez C, Allart JC, Leclaire M. Bombart, et al. Among authors: leclaire m. Bull Soc Fr Dermatol Syphiligr. 1970;77(3):360-2. Bull Soc Fr Dermatol Syphiligr. 1970. PMID: 4101792 German. No abstract available.
88 results