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Page 1
Plasma myo-inositol elevation in heart failure: clinical implications and prognostic significance. Results from the BElgian and CAnadian MEtabolomics in HFpEF (BECAME-HF) research project.
Pouleur AC, Menghoum N, Cumps J, Marino A, Badii M, Lejeune S, Legault JT, Boucher G, Gruson D, Roy C, Battault S, Mahrouche L, Pedneault-Gagnon V, Charpentier D, Furtos A, Hussin J, Rhainds D, Tardif JC, Bertrand L, Rosiers CD, Horman S, Beauloye C. Pouleur AC, et al. Among authors: legault jt. EBioMedicine. 2024 Sep;107:105264. doi: 10.1016/j.ebiom.2024.105264. Epub 2024 Aug 8. EBioMedicine. 2024. PMID: 39121579 Free PMC article.
A pilot study to identify blood-based markers associated with response to treatment with Vedolizumab in patients with Inflammatory Bowel Disease.
Rioux JD, Boucher G, Forest A, Bouchard B, Coderre L, Daneault C, Frayne IR, Legault JT; iGenoMed Consortium; Bitton A, Ananthakrishnan A, Lesage S, Xavier RJ, Des Rosiers C. Rioux JD, et al. Among authors: legault jt. medRxiv [Preprint]. 2024 Sep 22:2024.09.19.24314034. doi: 10.1101/2024.09.19.24314034. medRxiv. 2024. Update in: Immunol Cell Biol. 2025 Aug;103(7):648-663. doi: 10.1111/imcb.70039. PMID: 39371119 Free PMC article. Updated. Preprint.
Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti-integrin therapy.
Rioux JD, Boucher G, Forest A, Bouchard B, Coderre L, Daneault C, Frayne IR, Legault JT, Bitton A, Ananthakrishnan A, Lesage S, Xavier RJ, Des Rosiers C; iGenoMed Consortium. Rioux JD, et al. Among authors: legault jt. Immunol Cell Biol. 2025 Aug;103(7):648-663. doi: 10.1111/imcb.70039. Epub 2025 Jun 12. Immunol Cell Biol. 2025. PMID: 40509637 Free PMC article.
Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder.
Ruiz M, Cuillerier A, Daneault C, Deschênes S, Frayne IR, Bouchard B, Forest A, Legault JT; LSFC Consortium; Vaz FM, Rioux JD, Burelle Y, Des Rosiers C. Ruiz M, et al. Among authors: legault jt. JCI Insight. 2019 Jul 25;4(14):e123231. doi: 10.1172/jci.insight.123231. eCollection 2019 Jul 25. JCI Insight. 2019. PMID: 31341105 Free PMC article.
Functional screen of inflammatory bowel disease genes reveals key epithelial functions.
Ntunzwenimana JC, Boucher G, Paquette J, Gosselin H, Alikashani A, Morin N, Beauchamp C, Thauvette L, Rivard MÈ, Dupuis F, Deschênes S, Foisy S, Latour F, Lavallée G, Daly MJ, Xavier RJ; iGenoMed Consortium; Charron G, Goyette P, Rioux JD. Ntunzwenimana JC, et al. Genome Med. 2021 Nov 11;13(1):181. doi: 10.1186/s13073-021-00996-7. Genome Med. 2021. PMID: 34758847 Free PMC article.
Frequency enrichment of coding variants in a French-Canadian founder population and its implication for inflammatory bowel diseases.
Bhérer C, Grenier JC, Pelletier J, Boucher G, Gagnon G, Goyette P, Ashton-Beaucage D, Stevens C, Battat R, Bitton A, Campeau PM, Laprise C; NIDDK IBD Genetics Consortium; Quebec IBD Genetics Consortium; iGenoMed Consortium; Huang H, Daly M, Taliun D, Hussin JG, Mooser V, Rioux JD. Bhérer C, et al. medRxiv [Preprint]. 2025 Jul 14:2025.07.11.25331388. doi: 10.1101/2025.07.11.25331388. medRxiv. 2025. PMID: 40791678 Free PMC article. Preprint.