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72 results

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Page 1
Safety, immunogenicity and effect on viral rebound of HTI vaccines combined with a TLR7 agonist in early-treated HIV-1 infection: a randomized, placebo-controlled phase 2a trial.
Bailón L, Moltó J, Curran A, Cadiñanos J, Carlos Lopez Bernaldo de Quirós J, de Los Santos I, Ambrosioni J, Imaz A, Benet S, Suanzes P, Navarro J, González-García J, Busca C, Pérez-Latorre L, Berenguer J, García-Fraile LJ, Mejía-Abril G, Miró JM, Scévola S, Moreno S, Domingo P, Tian Y, Frankot M, Lim D, Cai Y, Vendrame E, Guo S, Wallin JJ, Geleziunas R, SenGupta D, Alarcón-Soto Y, Leal I, Aranguen A, Garcia-Garcia M, McGowan I, Brander C, Arribas JR, Mothe B; AELIX-003 Study Group. Bailón L, et al. Nat Commun. 2025 Mar 4;16(1):2146. doi: 10.1038/s41467-025-57284-w. Nat Commun. 2025. PMID: 40038256 Free PMC article. Clinical Trial.
A minor population of macrophage-tropic HIV-1 variants is identified in recrudescing viremia following analytic treatment interruption.
Andrade VM, Mavian C, Babic D, Cordeiro T, Sharkey M, Barrios L, Brander C, Martinez-Picado J, Dalmau J, Llano A, Li JZ, Jacobson J, Lavine CL, Seaman MS, Salemi M, Stevenson M. Andrade VM, et al. Among authors: llano a. Proc Natl Acad Sci U S A. 2020 May 5;117(18):9981-9990. doi: 10.1073/pnas.1917034117. Epub 2020 Apr 16. Proc Natl Acad Sci U S A. 2020. PMID: 32300019 Free PMC article.
Sirtuin-2, NAD-Dependent Deacetylase, Is a New Potential Therapeutic Target for HIV-1 Infection and HIV-Related Neurological Dysfunction.
Duran-Castells C, Llano A, Kawana-Tachikawa A, Prats A, Martinez-Zalacain I, Kobayashi-Ishihara M, Oriol-Tordera B, Peña R, Gálvez C, Silva-Arrieta S, Clotet B, Riveira-Muñoz E, Ballana E, Prado JG, Martinez-Picado J, Sanchez J, Mothe B, Hartigan-O'Connor D, Wyss-Coray T, Meyerhans A, Gisslén M, Price RW, Soriano-Mas C, Muñoz-Moreno JA, Brander C, Ruiz-Riol M. Duran-Castells C, et al. Among authors: llano a. J Virol. 2023 Feb 28;97(2):e0165522. doi: 10.1128/jvi.01655-22. Epub 2023 Jan 31. J Virol. 2023. PMID: 36719240 Free PMC article.
Plasma proteomic profiling identifies CD33 as a marker of HIV control in natural infection and after therapeutic vaccination.
Duran-Castells C, Prats A, Oriol-Tordera B, Llano A, Galvez C, Martinez-Picado J, Ballana E, Garcia-Vidal E, Clotet B, Muñoz-Moreno JA, Hanke T, Moltó J, Mothe B, Brander C, Ruiz-Riol M. Duran-Castells C, et al. Among authors: llano a. EBioMedicine. 2023 Sep;95:104732. doi: 10.1016/j.ebiom.2023.104732. Epub 2023 Jul 26. EBioMedicine. 2023. PMID: 37506557 Free PMC article. Clinical Trial.
A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques.
Mothe B, Hu X, Llano A, Rosati M, Olvera A, Kulkarni V, Valentin A, Alicea C, Pilkington GR, Sardesai NY, Rocafort M, Crespo M, Carrillo J, Marco A, Mullins JI, Dorrell L, Hanke T, Clotet B, Pavlakis GN, Felber BK, Brander C. Mothe B, et al. Among authors: llano a. J Transl Med. 2015 Feb 15;13:60. doi: 10.1186/s12967-015-0392-5. J Transl Med. 2015. PMID: 25879820 Free PMC article.
Safety, immunogenicity and effect on viral rebound of HTI vaccines in early treated HIV-1 infection: a randomized, placebo-controlled phase 1 trial.
Bailón L, Llano A, Cedeño S, Escribà T, Rosás-Umbert M, Parera M, Casadellà M, Lopez M, Pérez F, Oriol-Tordera B, Ruiz-Riol M, Coll J, Perez F, Rivero À, Leselbaum AR, McGowan I, Sengupta D, Wee EG, Hanke T, Paredes R, Alarcón-Soto Y, Clotet B, Noguera-Julian M, Brander C, Molto J, Mothe B; AELIX002 Study Group. Bailón L, et al. Among authors: llano a. Nat Med. 2022 Dec;28(12):2611-2621. doi: 10.1038/s41591-022-02060-2. Epub 2022 Oct 27. Nat Med. 2022. PMID: 36302893 Clinical Trial.
Mechanisms of Abrupt Loss of Virus Control in a Cohort of Previous HIV Controllers.
Rosás-Umbert M, Llano A, Bellido R, Olvera A, Ruiz-Riol M, Rocafort M, Fernández MA, Cobarsi P, Crespo M, Dorrell L, Del Romero J, Alcami J, Paredes R, Brander C, Mothe B. Rosás-Umbert M, et al. Among authors: llano a. J Virol. 2019 Feb 5;93(4):e01436-18. doi: 10.1128/JVI.01436-18. Print 2019 Feb 15. J Virol. 2019. PMID: 30487276 Free PMC article.
72 results