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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1970 1
1976 1
1981 2
1983 4
1984 2
1986 1
1987 5
1988 10
1989 4
1990 5
1991 5
1992 6
1993 2
1994 11
1995 6
1996 7
1997 5
1998 5
1999 11
2000 10
2001 9
2002 7
2003 7
2004 15
2005 12
2006 10
2007 17
2008 25
2009 14
2010 20
2011 30
2012 26
2013 24
2014 28
2015 26
2016 26
2017 5
2018 6
2019 13
2020 17
2021 16
2022 12
2023 13
2024 18
2025 8

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443 results

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Page 1
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia.
Krivtsov AV, Evans K, Gadrey JY, Eschle BK, Hatton C, Uckelmann HJ, Ross KN, Perner F, Olsen SN, Pritchard T, McDermott L, Jones CD, Jing D, Braytee A, Chacon D, Earley E, McKeever BM, Claremon D, Gifford AJ, Lee HJ, Teicher BA, Pimanda JE, Beck D, Perry JA, Smith MA, McGeehan GM, Lock RB, Armstrong SA. Krivtsov AV, et al. Among authors: lock rb. Cancer Cell. 2019 Dec 9;36(6):660-673.e11. doi: 10.1016/j.ccell.2019.11.001. Cancer Cell. 2019. PMID: 31821784 Free PMC article.
Precision-guided treatment in high-risk pediatric cancers.
Lau LMS, Khuong-Quang DA, Mayoh C, Wong M, Barahona P, Ajuyah P, Senapati A, Nagabushan S, Sherstyuk A, Altekoester AK, Fuentes-Bolanos NA, Yeung V, Sullivan A, Omer N, Diamond Y, Jessop S, Battaglia L, Zhukova N, Cui L, Lin A, Gifford AJ, Fleuren EDG, Dalla-Pozza L, Moore AS, Khaw SL, Eisenstat DD, Gottardo NG, Wood PJ, Tapp H, Alvaro F, McCowage G, Nicholls W, Hansford JR, Manoharan N, Kotecha RS, Mateos MK, Lock RB, Tyrrell V, Haber M, Trahair TN, Cowley MJ, Ekert PG, Marshall GM, Ziegler DS. Lau LMS, et al. Among authors: lock rb. Nat Med. 2024 Jul;30(7):1913-1922. doi: 10.1038/s41591-024-03044-0. Epub 2024 Jun 6. Nat Med. 2024. PMID: 38844796 Free PMC article.
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer.
Wong M, Mayoh C, Lau LMS, Khuong-Quang DA, Pinese M, Kumar A, Barahona P, Wilkie EE, Sullivan P, Bowen-James R, Syed M, Martincorena I, Abascal F, Sherstyuk A, Bolanos NA, Baber J, Priestley P, Dolman MEM, Fleuren EDG, Gauthier ME, Mould EVA, Gayevskiy V, Gifford AJ, Grebert-Wade D, Strong PA, Manouvrier E, Warby M, Thomas DM, Kirk J, Tucker K, O'Brien T, Alvaro F, McCowage GB, Dalla-Pozza L, Gottardo NG, Tapp H, Wood P, Khaw SL, Hansford JR, Moore AS, Norris MD, Trahair TN, Lock RB, Tyrrell V, Haber M, Marshall GM, Ziegler DS, Ekert PG, Cowley MJ. Wong M, et al. Among authors: lock rb. Nat Med. 2020 Nov;26(11):1742-1753. doi: 10.1038/s41591-020-1072-4. Epub 2020 Oct 5. Nat Med. 2020. PMID: 33020650
High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer.
Mayoh C, Mao J, Xie J, Tax G, Chow SO, Cadiz R, Pazaky K, Barahona P, Ajuyah P, Trebilcock P, Malquori A, Gunther K, Avila A, Yun DY, Alfred S, Gopalakrishnan A, Kamili A, Wong M, Cowley MJ, Jessop S, Lau LMS, Trahair TN, Ziegler DS, Fletcher JI, Gifford AJ, Tsoli M, Marshall GM, Haber M, Tyrrell V, Failes TW, Arndt GM, Lock RB, Ekert PG, Dolman MEM. Mayoh C, et al. Among authors: lock rb. Cancer Res. 2023 Aug 15;83(16):2716-2732. doi: 10.1158/0008-5472.CAN-22-3702. Cancer Res. 2023. PMID: 37523146 Free PMC article.
TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells.
Truong P, Shen S, Joshi S, Islam MI, Zhong L, Raftery MJ, Afrasiabi A, Alinejad-Rokny H, Nguyen M, Zou X, Bhuyan GS, Sarowar CH, Ghodousi ES, Stonehouse O, Mohamed S, Toscan CE, Connerty P, Kakadia PM, Bohlander SK, Michie KA, Larsson J, Lock RB, Walkley CR, Thoms JAI, Jolly CJ, Pimanda JE. Truong P, et al. Among authors: lock rb. Nat Commun. 2024 Aug 28;15(1):7360. doi: 10.1038/s41467-024-51646-6. Nat Commun. 2024. PMID: 39198401 Free PMC article.
PU.1 eviction at lymphocyte-specific chromatin domains mediates glucocorticoid response in acute lymphoblastic leukemia.
Beck D, Cao H, Tian F, Huang Y, Jiang M, Zhao H, Tai X, Xu W, Kosasih HJ, Kealy DJ, Zhao W, Taylor SJ, Couttas TA, Song G, Chacon-Fajardo D, Walia Y, Wang M, Dowle AA, Holding AN, Bridge KS, Zhang C, Wang J, Mi JQ, Lock RB, de Bock CE, Jing D. Beck D, et al. Among authors: lock rb. Nat Commun. 2024 Nov 8;15(1):9697. doi: 10.1038/s41467-024-54096-2. Nat Commun. 2024. PMID: 39516193 Free PMC article.
Modeling the Effects of Protracted Cosmic Radiation in a Human Organ-on-Chip Platform.
Tavakol DN, Nash TR, Kim Y, Graney PL, Liberman M, Fleischer S, Lock RI, O'Donnell A, Andrews L, Ning D, Yeager K, Harken A, Deoli N, Amundson SA, Garty G, Leong KW, Brenner DJ, Vunjak-Novakovic G. Tavakol DN, et al. Among authors: lock ri. Adv Sci (Weinh). 2024 Nov;11(42):e2401415. doi: 10.1002/advs.202401415. Epub 2024 Jul 4. Adv Sci (Weinh). 2024. PMID: 38965824 Free PMC article.
Ras, autophagy and glycolysis.
Lock R, Debnath J. Lock R, et al. Cell Cycle. 2011 May 15;10(10):1516-7. doi: 10.4161/cc.10.10.15434. Epub 2011 May 15. Cell Cycle. 2011. PMID: 21467842 No abstract available.
Circulating Tumor DNA in Pediatric Cancer.
Doculara L, Trahair TN, Bayat N, Lock RB. Doculara L, et al. Among authors: lock rb. Front Mol Biosci. 2022 May 12;9:885597. doi: 10.3389/fmolb.2022.885597. eCollection 2022. Front Mol Biosci. 2022. PMID: 35647029 Free PMC article. Review.
Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy.
Wang BZ, Morsink MA, Kim SW, Luo LJ, Zhang X, Soni RK, Lock RI, Rao J, Kim Y, Zhang A, Neyazi M, Gorham JM, Kim Y, Brown K, DeLaughter DM, Zhang Q, McDonough B, Watkins JM, Cunningham KM, Oudit GY, Fine BM, Seidman CE, Seidman JG, Vunjak-Novakovic G. Wang BZ, et al. Among authors: lock ri. J Clin Invest. 2025 Jan 2;135(1):e181630. doi: 10.1172/JCI181630. J Clin Invest. 2025. PMID: 39744939 Free PMC article.
443 results