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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1969 3
1970 2
1981 1
1984 1
1985 3
1986 1
1987 3
1988 5
1989 2
1990 4
1991 5
1992 6
1993 7
1994 5
1995 6
1996 7
1997 4
1998 8
1999 14
2000 8
2001 13
2002 11
2003 22
2004 10
2005 11
2006 27
2007 23
2008 22
2009 25
2010 24
2011 36
2012 22
2013 27
2014 18
2015 38
2016 26
2017 26
2018 34
2019 42
2020 48
2021 58
2022 54
2023 49
2024 58
2025 66

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823 results

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Page 1
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice.
Zhang Z, Tian X, Lu JY, Boit K, Ablaeva J, Zakusilo FT, Emmrich S, Firsanov D, Rydkina E, Biashad SA, Lu Q, Tyshkovskiy A, Gladyshev VN, Horvath S, Seluanov A, Gorbunova V. Zhang Z, et al. Among authors: lu jy. Nature. 2023 Sep;621(7977):196-205. doi: 10.1038/s41586-023-06463-0. Epub 2023 Aug 23. Nature. 2023. PMID: 37612507 Free PMC article.
Phase separation of RNA-binding protein promotes polymerase binding and transcription.
Shao W, Bi X, Pan Y, Gao B, Wu J, Yin Y, Liu Z, Peng M, Zhang W, Jiang X, Ren W, Xu Y, Wu Z, Wang K, Zhan G, Lu JY, Han X, Li T, Wang J, Li G, Deng H, Li B, Shen X. Shao W, et al. Among authors: lu jy. Nat Chem Biol. 2022 Jan;18(1):70-80. doi: 10.1038/s41589-021-00904-5. Epub 2021 Dec 16. Nat Chem Biol. 2022. PMID: 34916619
Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence.
Han X, Xing L, Hong Y, Zhang X, Hao B, Lu JY, Huang M, Wang Z, Ma S, Zhan G, Li T, Hao X, Tao Y, Li G, Zhou S, Zheng Z, Shao W, Zeng Y, Ma D, Zhang W, Xie Z, Deng H, Yan J, Deng W, Shen X. Han X, et al. Among authors: lu jy. Cell Stem Cell. 2024 May 2;31(5):694-716.e11. doi: 10.1016/j.stem.2024.03.015. Epub 2024 Apr 16. Cell Stem Cell. 2024. PMID: 38631356 Free article.
Disagreement on foundational principles of biological aging.
Gladyshev VN, Anderson B, Barlit H, Barré B, Beck S, Behrouz B, Belsky DW, Chaix A, Chamoli M, Chen BH, Cheng K, Chuprin J, Churchill GA, Cipriano A, Colville A, Deelen J, Deigin Y, Edmonds KK, English BW, Fang R, Florea M, Gershteyn IM, Gill D, Goetz LH, Gorbunova V, Griffin PT, Horvath S, Borch Jensen M, Jin X, Jovanovska S, Kajderowicz KM, Kasahara T, Kerepesi C, Kulkarni S, Labunskyy VM, Levine ME, Libert S, Lu JY, Lu YR, Marioni RE, McCoy BM, Mitchell W, Moqri M, Nasirian F, Niimi P, Oh HS, Okundaye B, Parkhitko AA, Peshkin L, Petljak M, Poganik JR, Pridham G, Promislow DEL, Prusisz W, Quiniou M, Raj K, Richard D, Ricon JL, Rutledge J, Scheibye-Knudsen M, Schork NJ, Seluanov A, Shadpour M, Shindyapina AV, Shuken SR, Sivakumar S, Stoeger T, Sugiura A, Sutton NR, Suvorov A, Tarkhov AE, Teeling EC, Trapp A, Tyshkovskiy A, Unfried M, Ward-Caviness CK, Yim SH, Ying K, Yunes J, Zhang B, Zhavoronkov A. Gladyshev VN, et al. Among authors: lu jy. PNAS Nexus. 2024 Dec 3;3(12):pgae499. doi: 10.1093/pnasnexus/pgae499. eCollection 2024 Dec. PNAS Nexus. 2024. PMID: 39660064 Free PMC article.
Hydroxyurea ameliorates atherosclerosis in ApoE-/- mice by potentially modulating Niemann-Pick C1-like 1 protein through the gut microbiota.
Yang XY, Yu H, Fu J, Guo HH, Han P, Ma SR, Pan LB, Zhang ZW, Xu H, Hu JC, Zhang HJ, Bu MM, Zhang XF, Yang W, Wang JY, Jin JY, Zhang HC, Li DR, Lu JY, Lin Y, Jiang JD, Tong Q, Wang Y. Yang XY, et al. Among authors: lu jy. Theranostics. 2022 Nov 14;12(18):7775-7787. doi: 10.7150/thno.76805. eCollection 2022. Theranostics. 2022. PMID: 36451858 Free PMC article.
DNA repair and anti-cancer mechanisms in the long-lived bowhead whale.
Firsanov D, Zacher M, Tian X, Sformo TL, Zhao Y, Tombline G, Lu JY, Zheng Z, Perelli L, Gurreri E, Zhang L, Guo J, Korotkov A, Volobaev V, Biashad SA, Zhang Z, Heid J, Maslov A, Sun S, Wu Z, Gigas J, Hillpot E, Martinez J, Lee M, Williams A, Gilman A, Hamilton N, Haseljic E, Patel A, Straight M, Miller N, Ablaeva J, Tam LM, Couderc C, Hoopman M, Moritz R, Fujii S, Hayman DJ, Liu H, Cai Y, Leung AKL, Simons MJP, Zhang Z, Nelson CB, Abegglen LM, Schiffman JD, Gladyshev VN, Modesti M, Genovese G, Vijg J, Seluanov A, Gorbunova V. Firsanov D, et al. Among authors: lu jy. bioRxiv [Preprint]. 2024 Nov 5:2023.05.07.539748. doi: 10.1101/2023.05.07.539748. bioRxiv. 2024. PMID: 39574710 Free PMC article. Preprint.
823 results