Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1962 1
1963 1
1964 1
1966 1
1968 1
1974 1
1975 2
1978 1
1979 1
1981 1
1982 1
1984 1
1989 5
1990 1
1991 1
1992 3
1993 4
1994 3
1995 6
1996 5
1997 5
1998 9
1999 8
2000 14
2001 12
2002 13
2003 19
2004 18
2005 17
2006 16
2007 24
2008 27
2009 29
2010 38
2011 28
2012 34
2013 26
2014 27
2015 35
2016 32
2017 20
2018 22
2019 21
2020 26
2021 26
2022 37
2023 27
2024 35
2025 34

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

654 results

Results by year

Filters applied: . Clear all
Page 1
A GIPR antagonist conjugated to GLP-1 analogues promotes weight loss with improved metabolic parameters in preclinical and phase 1 settings.
Véniant MM, Lu SC, Atangan L, Komorowski R, Stanislaus S, Cheng Y, Wu B, Falsey JR, Hager T, Thomas VA, Ambhaikar M, Sharpsten L, Zhu Y, Kurra V, Jeswani R, Oberoi RK, Parnes JR, Honarpour N, Neutel J, Strande JL. Véniant MM, et al. Among authors: lu sc. Nat Metab. 2024 Feb;6(2):290-303. doi: 10.1038/s42255-023-00966-w. Epub 2024 Feb 5. Nat Metab. 2024. PMID: 38316982 Free PMC article. Clinical Trial.
Glutathione synthesis.
Lu SC. Lu SC. Biochim Biophys Acta. 2013 May;1830(5):3143-53. doi: 10.1016/j.bbagen.2012.09.008. Epub 2012 Sep 17. Biochim Biophys Acta. 2013. PMID: 22995213 Free PMC article. Review.
Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment.
Wang Z, Kim SY, Tu W, Kim J, Xu A, Yang YM, Matsuda M, Reolizo L, Tsuchiya T, Billet S, Gangi A, Noureddin M, Falk BA, Kim S, Fan W, Tighiouart M, You S, Lewis MS, Pandol SJ, Di Vizio D, Merchant A, Posadas EM, Bhowmick NA, Lu SC, Seki E. Wang Z, et al. Among authors: lu sc. Cell Metab. 2023 Jul 11;35(7):1209-1226.e13. doi: 10.1016/j.cmet.2023.04.013. Epub 2023 May 11. Cell Metab. 2023. PMID: 37172577 Free PMC article.
GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys.
Lu SC, Chen M, Atangan L, Killion EA, Komorowski R, Cheng Y, Netirojjanakul C, Falsey JR, Stolina M, Dwyer D, Hale C, Stanislaus S, Hager T, Thomas VA, Harrold JM, Lloyd DJ, Véniant MM. Lu SC, et al. Cell Rep Med. 2021 Apr 30;2(5):100263. doi: 10.1016/j.xcrm.2021.100263. eCollection 2021 May 18. Cell Rep Med. 2021. PMID: 34095876 Free PMC article.
Metabolomic-based aging clocks.
Ibáñez de Opakua A, Conde R, de Diego A, Bizkarguenaga M, Embade N, Lu SC, Mato JM, Millet O. Ibáñez de Opakua A, et al. Among authors: lu sc. NPJ Metab Health Dis. 2025 Sep 3;3(1):35. doi: 10.1038/s44324-025-00078-x. NPJ Metab Health Dis. 2025. PMID: 40903544 Free PMC article. Review.
Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models.
Killion EA, Wang J, Yie J, Shi SD, Bates D, Min X, Komorowski R, Hager T, Deng L, Atangan L, Lu SC, Kurzeja RJM, Sivits G, Lin J, Chen Q, Wang Z, Thibault SA, Abbott CM, Meng T, Clavette B, Murawsky CM, Foltz IN, Rottman JB, Hale C, Véniant MM, Lloyd DJ. Killion EA, et al. Among authors: lu sc. Sci Transl Med. 2018 Dec 19;10(472):eaat3392. doi: 10.1126/scitranslmed.aat3392. Sci Transl Med. 2018. PMID: 30567927
The role of forkhead box M1-methionine adenosyltransferase 2 A/2B axis in liver inflammation and fibrosis.
Yang B, Lu L, Xiong T, Fan W, Wang J, Barbier-Torres L, Chhimwal J, Sinha S, Tsuchiya T, Mavila N, Tomasi ML, Cao D, Zhang J, Peng H, Mato JM, Liu T, Yang X, Kalinichenko VV, Ramani K, Han J, Seki E, Yang H, Lu SC. Yang B, et al. Among authors: lu sc. Nat Commun. 2024 Sep 27;15(1):8388. doi: 10.1038/s41467-024-52527-8. Nat Commun. 2024. PMID: 39333125 Free PMC article.
Metastatic tumor growth in steatotic liver is promoted by HAS2-mediated fibrotic tumor microenvironment.
Yang YM, Kim J, Wang Z, Kim J, Kim SY, Cho GJ, Lee JH, Kim SM, Tsuchiya T, Matsuda M, Pandyarajan V, Pandol SJ, Lewis MS, Gangi A, Noble PW, Jiang D, Merchant A, Posadas EM, Bhowmick NA, Lu SC, You S, Xu AM, Seki E. Yang YM, et al. Among authors: lu sc. J Clin Invest. 2025 Feb 13;135(7):e180802. doi: 10.1172/JCI180802. J Clin Invest. 2025. PMID: 39946200 Free PMC article.
GIPR-Ab/GLP-1 peptide-antibody conjugate requires brain GIPR and GLP-1R for additive weight loss in obese mice.
Liu CM, Killion EA, Hammoud R, Lu SC, Komorowski R, Liu T, Kanke M, Thomas VA, Cook K, Sivits GN Jr, Ben AB, Atangan LI, Hussien R, Tang A, Shkumatov A, Li CM, Drucker DJ, Véniant MM. Liu CM, et al. Among authors: lu sc. Nat Metab. 2025 Jun;7(6):1266-1281. doi: 10.1038/s42255-025-01295-w. Epub 2025 Apr 29. Nat Metab. 2025. PMID: 40301582 Free PMC article.
654 results