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. 1978 Oct 19;275(5681):611-7.
doi: 10.1038/275611a0.

DNA sequence of the mini-insertion IS2--6 and its relation to the sequence of IS2

D Ghosal, H Saedler

DNA sequence of the mini-insertion IS2--6 and its relation to the sequence of IS2

D Ghosal et al. Nature. .

Abstract

In polar IS2 abolishes galactose operon expression. Operon activity is restored by a 108 base pair mini-insertion within IS2 called IS2--6. The DNA sequences of the gal operon-IS2 junction, the parental IS2 region undergoing sequence rearrangements and IS2--6 itself are reported. IS2--6 is composed of sequence intervals present in both strands of IS2.

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