Termination region in rRNA genes from a eucaryotic thermophile, Thermomyces lanuginosus
- PMID: 2294410
- PMCID: PMC360758
- DOI: 10.1128/mcb.10.1.377-381.1990
Termination region in rRNA genes from a eucaryotic thermophile, Thermomyces lanuginosus
Abstract
S1 mapping of the termination region in the ribosomal DNA from a thermophilic fungus, Thermomyces lanuginosus, revealed three distinct termini corresponding to the mature 25S rRNA, a precursor that is 19 nucleotides longer and corresponds to the 37S precursor in yeast cells, and a putative termination site at +96 that bears a limited sequence homology with the SalI box of mammalian cells. An estimate of the secondary structure suggested that the three termini are in close proximity, a feature that may be essential to precursor termination and maturation. The results raise questions regarding recently reported relationships between ribosomal DNA termination and spacer enhancer elements in fungi.
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