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Comparative Study
. 1992 May 15;89(10):4663-7.
doi: 10.1073/pnas.89.10.4663.

Dodeca satellite: a conserved G+C-rich satellite from the centromeric heterochromatin of Drosophila melanogaster

J P Abad  1 , M Carmena, S Baars, R D Saunders, D M Glover, P Ludeña, C Sentis, C Tyler-Smith, A Villasante
Affiliations
Comparative Study

Dodeca satellite: a conserved G+C-rich satellite from the centromeric heterochromatin of Drosophila melanogaster

J P Abad et al. Proc Natl Acad Sci U S A. .

Abstract

To identify sequences from the centromeric region, we have constructed a Drosophila melanogaster yeast artificial chromosome (YAC) library and screened it with purified DNA from the minichromosome Dp(1;f)1187 derived from the X chromosome. We describe the structure of one clone isolated in this way. This YAC is structurally unstable and contains tandemly repeated G+C-rich 11-mer and 12-mer units, which we call dodeca satellite. Most of this satellite is located near the centromere of an autosome. Cross-hybridizing sequences are found in the genomes of organisms as distant as Arabidopsis thaliana and Homo sapiens.

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References

    1. Cell. 1990 Oct 5;63(1):97-107 - PubMed
    1. Science. 1970 Jun 12;168(3937):1356-8 - PubMed
    1. Nucleic Acids Res. 1989 May 11;17(9):3425-33 - PubMed
    1. J Mol Biol. 1986 Jan 20;187(2):145-55 - PubMed
    1. Science. 1987 May 15;236(4803):806-12 - PubMed

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