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Page 1
Showing results for maa g eg
Search for Maag EG instead (1 results)
Pegcetacoplan controls hemolysis in complement inhibitor-naive patients with paroxysmal nocturnal hemoglobinuria.
Wong RSM, Navarro-Cabrera JR, Comia NS, Goh YT, Idrobo H, Kongkabpan D, Gómez-Almaguer D, Al-Adhami M, Ajayi T, Alvarenga P, Savage J, Deschatelets P, Francois C, Grossi F, Dumagay T. Wong RSM, et al. Blood Adv. 2023 Jun 13;7(11):2468-2478. doi: 10.1182/bloodadvances.2022009129. Blood Adv. 2023. PMID: 36848639 Free PMC article. Clinical Trial.
PRINCE was a phase 3, randomized, multicenter, open-label, controlled study to evaluate the efficacy and safety of pegcetacoplan vs control (supportive care only; eg, blood transfusions, corticosteroids, and supplements) in complement inhibitor-naive patients with PNH. ... …
PRINCE was a phase 3, randomized, multicenter, open-label, controlled study to evaluate the efficacy and safety of pegcetacoplan vs control …
Artificial intelligence for individualized treatment of persistent atrial fibrillation: a randomized controlled trial.
Deisenhofer I, Albenque JP, Busch S, Gitenay E, Mountantonakis SE, Roux A, Horvilleur J, Bakouboula B, Oza S, Abbey S, Theodore G, Lepillier A, Guyomar Y, Bessiere F, Jan Smit J, Mohr Durdez T, Milpied P, Appetiti A, Guerrero D, De Potter T, De Chillou C, Goldbarg S, Verma A, Hummel JD; TAILORED-AF Investigators. Deisenhofer I, et al. Nat Med. 2025 Apr;31(4):1286-1293. doi: 10.1038/s41591-025-03517-w. Epub 2025 Feb 14. Nat Med. 2025. PMID: 39953289 Free PMC article. Clinical Trial.
Preparation of poly(MAA-g-EG) hydrogel nanoparticles by a thermally-initiated free radical dispersion polymerization.
Deng L, He X, Li A, Yang Q, Dong A. Deng L, et al. J Nanosci Nanotechnol. 2007 Feb;7(2):626-33. J Nanosci Nanotechnol. 2007. PMID: 17450805
The reaction temperature at 75 degrees C was found to be suitable for preparing stable and small P(MAA-g-EG) HNPs. By adding a little amount of polyvinyl alcohol in the reaction media, P(MAA-g-EG) HNPs with narrow size distribution could …
The reaction temperature at 75 degrees C was found to be suitable for preparing stable and small P(MAA-g-EG) HNPs. By a …
Development of a P((MAA-co-NVP)-g-EG) Hydrogel Platform for Oral Protein Delivery: Effects of Hydrogel Composition on Environmental Response and Protein Partitioning.
Steichen S, O'Connor C, Peppas NA. Steichen S, et al. Macromol Biosci. 2017 Jan;17(1). doi: 10.1002/mabi.201600266. Epub 2016 Sep 30. Macromol Biosci. 2017. PMID: 27689827
Hydrogels based upon terpolymers of methacrylic acid, N-vinyl pyrrolidone, and poly(ethylene glycol) are developed and characterized for their ability to respond to changes in environmental pH and to partition protein therapeutics of varying molecular weights and isoelectric poin …
Hydrogels based upon terpolymers of methacrylic acid, N-vinyl pyrrolidone, and poly(ethylene glycol) are developed and characterized for the …
Oral insulin delivery using P(MAA-g-EG) hydrogels: effects of network morphology on insulin delivery characteristics.
Nakamura K, Murray RJ, Joseph JI, Peppas NA, Morishita M, Lowman AM. Nakamura K, et al. J Control Release. 2004 Mar 24;95(3):589-99. doi: 10.1016/j.jconrel.2003.12.022. J Control Release. 2004. PMID: 15023469
Hydrogels of poly(methacrylic acid-g-ethylene glycol) were prepared using different reaction water contents in order to vary the network mesh size, swelling behavior and insulin loading/release kinetics. ...
Hydrogels of poly(methacrylic acid-g-ethylene glycol) were prepared using different reaction water contents in order to vary the netw …
Effect of poly (ethylene glycol) molecular weight and microparticle size on oral insulin delivery from P(MAA-g-EG) microparticles.
López JE, Peppas NA. López JE, et al. Drug Dev Ind Pharm. 2004 May;30(5):497-504. doi: 10.1081/ddc-120037480. Drug Dev Ind Pharm. 2004. PMID: 15244085
Five years of successful work in our lab have shown that graft copolymer networks of poly(methacrylic acid-g-ethylene) [P(MAA-g-EG)], are very promising candidates for oral drug delivery. In an acidic environment, these copolymers form interpolymer com …
Five years of successful work in our lab have shown that graft copolymer networks of poly(methacrylic acid-g-ethylene) [P(MAA- …
Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function.
Della-Flora Nunes G, Osso LA, Haynes JA, Conant L, Thornton MA, Stockton ME, Brassell KA, Morris A, Mancha Corchado YI, Gaynes JA, Chavez AR, Woerner MB, MacKenna DA, Alavi A, Danks A, Poleg-Polsky A, Gandhi R, Vivian JA, Denman DJ, Hughes EG. Della-Flora Nunes G, et al. Nat Commun. 2025 Jan 16;16(1):732. doi: 10.1038/s41467-025-56092-6. Nat Commun. 2025. PMID: 39820244 Free PMC article.
T-cell recognition of melanoma-associated antigens.
Castelli C, Rivoltini L, Andreola G, Carrabba M, Renkvist N, Parmiani G. Castelli C, et al. J Cell Physiol. 2000 Mar;182(3):323-31. doi: 10.1002/(SICI)1097-4652(200003)182:3<323::AID-JCP2>3.0.CO;2-#. J Cell Physiol. 2000. PMID: 10653598 Review.
In this review, we summarize the significant progress that has been made in the identification of melanoma-associated antigens (MAA) recognized by cytotoxic T-lymphocytes (CTL). These antigens belong to three main groups: tumor-associated testis-specific antigens (e.g …
In this review, we summarize the significant progress that has been made in the identification of melanoma-associated antigens (MAA) …
PEGylated insulin loaded complexation hydrogels for protected oral delivery.
Coolich MK, Lanier OL, Cisneros E, Peppas NA. Coolich MK, et al. J Control Release. 2023 Dec;364:216-226. doi: 10.1016/j.jconrel.2023.10.020. Epub 2023 Oct 31. J Control Release. 2023. PMID: 37890591
In this work, we show that H-bonded, pH-sensitive poly(methacrylic acid-grafted ethylene glycol) glycol (henceforth designated as P(MAA-g-EG) gels) exhibit great promise as protein carriers, as they utilize poly(ethylene glycol) (PEG) chains to promote mucoad …
In this work, we show that H-bonded, pH-sensitive poly(methacrylic acid-grafted ethylene glycol) glycol (henceforth designated as P(MAA …
Nanogel-Integrated pH-Responsive Composite Hydrogels for Controlled Drug Delivery.
Cinay GE, Erkoc P, Alipour M, Hashimoto Y, Sasaki Y, Akiyoshi K, Kizilel S. Cinay GE, et al. ACS Biomater Sci Eng. 2017 Mar 13;3(3):370-380. doi: 10.1021/acsbiomaterials.6b00670. Epub 2017 Jan 31. ACS Biomater Sci Eng. 2017. PMID: 33465934
A novel pH-sensitive hydrogel system consisting of poly(methacrylic acid-g-ethylene glycol) (P(MAA-g-EG)) and acryloyl group modified-cholesterol-bearing pullulan (CHPOA) nanogels was developed for the controlled delivery of an anticonvulsant drug, pre …
A novel pH-sensitive hydrogel system consisting of poly(methacrylic acid-g-ethylene glycol) (P(MAA-g-EG)) and ac …
158 results