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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1992 1
1993 1
1997 1
1998 1
2001 1
2002 1
2003 2
2004 2
2005 4
2006 7
2007 8
2008 9
2009 12
2010 14
2011 3
2012 8
2013 14
2014 13
2015 12
2016 6
2017 11
2018 6
2019 11
2020 9
2021 7
2022 10
2023 5
2024 15
2025 11

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181 results

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Page 1
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction.
Simanshu DK, Xu R, Stice JP, Czyzyk DJ, Feng S, Denson JP, Riegler E, Yang Y, Zhang C, Donovan S, Smith BP, Abreu-Blanco M, Chen M, Feng C, Fu L, Rabara D, Young LC, Dyba M, Yan W, Lin K, Ghorbanpoorvalukolaie S, Larsen EK, Malik W, Champagne A, Parker K, Ju JH, Jeknic S, Esposito D, Turner DM, Lightstone FC, Wang B, Wehn PM, Wang K, Stephen AG, Maciag AE, Hata AN, Sinkevicius KW, Nissley DV, Wallace EM, McCormick F, Beltran PJ. Simanshu DK, et al. Among authors: maciag ae. Science. 2025 Jul 24;389(6758):409-415. doi: 10.1126/science.adq2004. Epub 2025 Jun 12. Science. 2025. PMID: 40504949
Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C.
Maciag AE, Stice JP, Wang B, Sharma AK, Chan AH, Lin K, Singh D, Dyba M, Yang Y, Setoodeh S, Smith BP, Ju JH, Jeknic S, Rabara D, Zhang Z, Larsen EK, Esposito D, Denson JP, Ranieri M, Meynardie M, Mehdizadeh S, Alexander PA, Abreu Blanco M, Turner DM, Xu R, Lightstone FC, Wong KK, Stephen AG, Wang K, Simanshu DK, Sinkevicius KW, Nissley DV, Wallace E, McCormick F, Beltran PJ. Maciag AE, et al. Cancer Discov. 2025 Mar 3;15(3):578-594. doi: 10.1158/2159-8290.CD-24-0840. Cancer Discov. 2025. PMID: 39642212 Free PMC article.
A Top-Down Proteomic Assay to Evaluate KRAS4B-Compound Engagement.
D'Ippolito RA, Rabara D, Blanco MA, Alberico E, Drew MR, Ramakrishnan N, Sontan D, Widmeyer SRT, Scheidemantle GM, Messing S, Turner D, Arkin M, Maciag AE, Stephen AG, Esposito D, McCormick F, Nissley DV, DeHart CJ. D'Ippolito RA, et al. Among authors: maciag ae. Anal Chem. 2024 Apr 2;96(13):5223-5231. doi: 10.1021/acs.analchem.3c05626. Epub 2024 Mar 18. Anal Chem. 2024. PMID: 38498381 Free PMC article.
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine.
Maciag AE, Yang Y, Sharma AK, Turner DM, DeHart CJ, Abdelkarim H, Fan L, Smith BP, Kumari V, Dyba M, Rigby M, Castillo Badillo JA, Adams L, Fornelli L, Fox S, Brafman A, Turbyville T, Gillette W, Messing S, Agamasu C, Wolfe AL, Gysin S, Chan AH, Simanshu DK, Esposito D, Chertov O, Stephen AG, Arkin M, Renslo A, Kelleher NL, Gaponenko V, Lightstone FC, Nissley DV, McCormick F. Maciag AE, et al. Proc Natl Acad Sci U S A. 2025 May 13;122(19):e2410766122. doi: 10.1073/pnas.2410766122. Epub 2025 May 9. Proc Natl Acad Sci U S A. 2025. PMID: 40343987 Free PMC article.
Taste receptor polymorphisms and longevity: a systematic review and meta-analysis.
Di Bona D, Malovini A, Accardi G, Aiello A, Candore G, Ferrario A, Ligotti ME, Maciag A, Puca AA, Caruso C. Di Bona D, et al. Among authors: maciag a. Aging Clin Exp Res. 2021 Sep;33(9):2369-2377. doi: 10.1007/s40520-020-01745-3. Epub 2020 Nov 10. Aging Clin Exp Res. 2021. PMID: 33170488 Free PMC article.
The TMD management dilemma.
Henien M, Zebic L, Mahendran K, Mellor A, Sproat C, Maciag A. Henien M, et al. Among authors: maciag a. Br Dent J. 2024 Jun;236(12):949-954. doi: 10.1038/s41415-024-7506-5. Epub 2024 Jun 28. Br Dent J. 2024. PMID: 38942856
181 results