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34 results

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Page 1
Disease diagnostics using machine learning of B cell and T cell receptor sequences.
Zaslavsky ME, Craig E, Michuda JK, Sehgal N, Ram-Mohan N, Lee JY, Nguyen KD, Hoh RA, Pham TD, Röltgen K, Lam B, Parsons ES, Macwana SR, DeJager W, Drapeau EM, Roskin KM, Cunningham-Rundles C, Moody MA, Haynes BF, Goldman JD, Heath JR, Chinthrajah RS, Nadeau KC, Pinsky BA, Blish CA, Hensley SE, Jensen K, Meyer E, Balboni I, Utz PJ, Merrill JT, Guthridge JM, James JA, Yang S, Tibshirani R, Kundaje A, Boyd SD. Zaslavsky ME, et al. Among authors: macwana sr. Science. 2025 Feb 21;387(6736):eadp2407. doi: 10.1126/science.adp2407. Epub 2025 Feb 21. Science. 2025. PMID: 39977494 Free PMC article.
Association of Autoantibody Concentrations and Trajectories With Lupus Nephritis Histologic Features and Treatment Response.
Fava A, Wagner CA, Guthridge CJ, Kheir J, Macwana S, DeJager W, Gross T, Izmirly P, Belmont HM, Diamond B, Davidson A, Utz PJ, Weisman MH, Magder LS; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Guthridge JM, Petri M, Buyon J, James JA. Fava A, et al. Among authors: macwana s. Arthritis Rheumatol. 2024 Nov;76(11):1611-1622. doi: 10.1002/art.42941. Epub 2024 Aug 9. Arthritis Rheumatol. 2024. PMID: 38962936
Ancestry-based differences in the immune phenotype are associated with lupus activity.
Slight-Webb S, Thomas K, Smith M, Wagner CA, Macwana S, Bylinska A, Donato M, Dvorak M, Chang SE, Kuo A, Cheung P, Kalesinskas L, Ganesan A, Dermadi D, Guthridge CJ, DeJager W, Wright C, Foecke MH, Merrill JT, Chakravarty E, Arriens C, Maecker HT, Khatri P, Utz PJ, James JA, Guthridge JM. Slight-Webb S, et al. Among authors: macwana s. JCI Insight. 2023 Aug 22;8(16):e169584. doi: 10.1172/jci.insight.169584. JCI Insight. 2023. PMID: 37606045 Free PMC article.
Genetic load in incomplete lupus erythematosus.
Slief M, Kheir JM, Smith M, Mowery C, Macwana S, DeJager W, Wagner CA, Aberle T, James JA, Guthridge JM. Slief M, et al. Among authors: macwana s. Lupus Sci Med. 2023 Jan;10(1):e000843. doi: 10.1136/lupus-2022-000843. Lupus Sci Med. 2023. PMID: 36599633 Free PMC article.
Sjögren's Syndrome Minor Salivary Gland CD4+ Memory T Cells Associate with Glandular Disease Features and have a Germinal Center T Follicular Helper Transcriptional Profile.
Joachims ML, Leehan KM, Dozmorov MG, Georgescu C, Pan Z, Lawrence C, Marlin MC, Macwana S, Rasmussen A, Radfar L, Lewis DM, Stone DU, Grundahl K, Scofield RH, Lessard CJ, Wren JD, Thompson LF, Guthridge JM, Sivils KL, Moore JS, Farris AD. Joachims ML, et al. Among authors: macwana s. J Clin Med. 2020 Jul 8;9(7):2164. doi: 10.3390/jcm9072164. J Clin Med. 2020. PMID: 32650575 Free PMC article.
Prospective SARS-CoV-2 Booster Vaccination in Immunosuppressant-Treated Systemic Autoimmune Disease Patients in a Randomized Controlled Trial.
Mackay M, Wagner CA, Pinckney A, Cohen JA, Wallace ZS, Khosroshahi A, Sparks JA, Lord S, Saxena A, Caricchio R, Kim AH, Kamen DL, Koumpouras F, Askanase AD, Smith K, Guthridge JM, Pardo G, Mao-Draayer Y, Macwana S, McCarthy S, Sherman MA, Hamrah SD, Veri M, Walker S, York K, Tedeschi S, Wang J, Dziubla G, Castro M, Carroll R, Narpala S, Lin BC, Serebryannyy L, McDermott A; ACV01 Study Team; Barry WT, Goldmuntz E, McNamara J, Payne AS, Bar-Or A, Khanna D, James JA. Mackay M, et al. Among authors: macwana s. medRxiv [Preprint]. 2025 Mar 26:2025.03.25.25324558. doi: 10.1101/2025.03.25.25324558. medRxiv. 2025. PMID: 40196267 Free PMC article. Preprint.
Disease diagnostics using machine learning of immune receptors.
Zaslavsky ME, Craig E, Michuda JK, Sehgal N, Ram-Mohan N, Lee JY, Nguyen KD, Hoh RA, Pham TD, Röltgen K, Lam B, Parsons ES, Macwana SR, DeJager W, Drapeau EM, Roskin KM, Cunningham-Rundles C, Moody MA, Haynes BF, Goldman JD, Heath JR, Nadeau KC, Pinsky BA, Blish CA, Hensley SE, Jensen K, Meyer E, Balboni I, Utz PJ, Merrill JT, Guthridge JM, James JA, Yang S, Tibshirani R, Kundaje A, Boyd SD. Zaslavsky ME, et al. Among authors: macwana sr. bioRxiv [Preprint]. 2024 Apr 3:2022.04.26.489314. doi: 10.1101/2022.04.26.489314. bioRxiv. 2024. Update in: Science. 2025 Feb 21;387(6736):eadp2407. doi: 10.1126/science.adp2407. PMID: 35547855 Free PMC article. Updated. Preprint.
A Flare Risk Index Informed by Select Immune Mediators in Systemic Lupus Erythematosus.
Munroe ME, Blankenship D, DeFreese D, Purushothaman M, DeJager W, Macwana S, Guthridge JM, Kamp S, Redinger N, Aberle T, Chakravarty EF, Arriens C, Li Y, Zeng H, McCarthy-Fruin KA, Osei-Onomahm SA, Thanarajasingam U, James JA, Jupe E. Munroe ME, et al. Among authors: macwana s. Arthritis Rheumatol. 2023 May;75(5):723-735. doi: 10.1002/art.42389. Epub 2023 Mar 6. Arthritis Rheumatol. 2023. PMID: 36245261 Free PMC article.
Characterising the autoantibody repertoire in systemic sclerosis following myeloablative haematopoietic stem cell transplantation.
Ayoglu B, Donato M, Furst DE, Crofford LJ, Goldmuntz E, Keyes-Elstein L, James J, Macwana S, Mayes MD, McSweeney P, Nash RA, Sullivan KM, Welch B, Pinckney A, Mao R, Chung L, Khatri P, Utz PJ. Ayoglu B, et al. Among authors: macwana s. Ann Rheum Dis. 2023 May;82(5):670-680. doi: 10.1136/ard-2021-221926. Epub 2023 Jan 18. Ann Rheum Dis. 2023. PMID: 36653124 Free PMC article.
34 results