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Page 1
Adaptive designs for dual-agent phase I dose-escalation studies.
Harrington JA, Wheeler GM, Sweeting MJ, Mander AP, Jodrell DI. Harrington JA, et al. Among authors: mander ap. Nat Rev Clin Oncol. 2013 May;10(5):277-88. doi: 10.1038/nrclinonc.2013.35. Epub 2013 Mar 19. Nat Rev Clin Oncol. 2013. PMID: 23507740 Review.
Investigating the effect of verapamil on preservation of beta-cell function in adults with newly diagnosed type 1 diabetes mellitus (Ver-A-T1D): protocol for a randomised, double-blind, placebo-controlled, parallel-group, multicentre trial.
Wych J, Brunner M, Stenson R, Chmura PJ, Danne T, Mander AP, Mathieu C, Dayan C, Pieber TR. Wych J, et al. Among authors: mander ap. BMJ Open. 2024 Nov 28;14(11):e091597. doi: 10.1136/bmjopen-2024-091597. BMJ Open. 2024. PMID: 39613428 Free PMC article.
Assessment of cognitive safety in clinical drug development.
Roiser JP, Nathan PJ, Mander AP, Adusei G, Zavitz KH, Blackwell AD. Roiser JP, et al. Among authors: mander ap. Drug Discov Today. 2016 Mar;21(3):445-53. doi: 10.1016/j.drudis.2015.11.003. Epub 2015 Nov 22. Drug Discov Today. 2016. PMID: 26610416 Free PMC article. Review.
Minimum effective low dose of antithymocyte globulin in people aged 5-25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial.
Mathieu C, Wych J, Hendriks AEJ, Van Ryckeghem L, Tree T, Chmura P, Möller C, Casteels K, Danne T, Reschke F, Šmigoc Schweiger D, Battelino T, Johannesen J, Rami-Merhar B, Pieber T, De Block C, Evans M, Hilbrands R, Bosi E, Willemsen RH, Basu S, Pulkkinen MA, Knip M, Cnop M, Nitsche A, Schulte AM, Niemöller E, Peakman M, Wilhelm-Benartzi C, Gillespie D, Overbergh L, Mander AP, Marcovecchio ML; INNODIA. Mathieu C, et al. Among authors: mander ap. Lancet. 2025 Sep 27;406(10510):1375-1388. doi: 10.1016/S0140-6736(25)01674-5. Epub 2025 Sep 18. Lancet. 2025. PMID: 40976248 Clinical Trial.
84 results