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Page 1
Showing results for maleate a
Search for Maoate A instead (1 results)
A new antihistaminic; chlor-trimeton maleate.
ALLISON JR, ROBINSON AM. ALLISON JR, et al. J S C Med Assoc (Columbia). 1949 Nov;45(11):344. J S C Med Assoc (Columbia). 1949. PMID: 15395598 No abstract available.
A large anisotropic plasticity of L-leucinium hydrogen maleate preserved at cryogenic temperatures.
Arkhipov SG, Losev EA, Nguyen TT, Rychkov DA, Boldyreva EV. Arkhipov SG, et al. Acta Crystallogr B Struct Sci Cryst Eng Mater. 2019 Apr 1;75(Pt 2):143-151. doi: 10.1107/S2052520619000441. Epub 2019 Mar 13. Acta Crystallogr B Struct Sci Cryst Eng Mater. 2019. PMID: 32830738
L-Leucinium hydrogen maleate crystals are very plastic at ambient conditions. Here it is shown that this plasticity is preserved at least down to 77 K. ...
L-Leucinium hydrogen maleate crystals are very plastic at ambient conditions. Here it is shown that this plasticity is preserved at l …
A covalent succinylcysteine-like intermediate in the enzyme-catalyzed transformation of maleate to fumarate by maleate isomerase.
Fisch F, Fleites CM, Delenne M, Baudendistel N, Hauer B, Turkenburg JP, Hart S, Bruce NC, Grogan G. Fisch F, et al. J Am Chem Soc. 2010 Aug 25;132(33):11455-7. doi: 10.1021/ja1053576. J Am Chem Soc. 2010. PMID: 20677745
Maleate isomerase (MI), a member of the Asp/Glu racemase superfamily, catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. Mutational studies, in conjunction with the structure of the C194A mutant of Nocardia farcinica MI cocrysta …
Maleate isomerase (MI), a member of the Asp/Glu racemase superfamily, catalyzes cis-trans isomerization of the C2-C3 double bond in …
Cellular Prion Protein Conformational Shift after Liquid-Liquid Phase Separation Regulated by a Polymeric Antagonist and Mutations.
Liu Y, Tuttle MD, Kostylev MA, Roseman GP, Zilm KW, Strittmatter SM. Liu Y, et al. J Am Chem Soc. 2024 Oct 9;146(40):27903-27914. doi: 10.1021/jacs.4c10590. Epub 2024 Sep 26. J Am Chem Soc. 2024. PMID: 39326869 Free PMC article.
Here, we report on a maturation process for the cellular prion protein (PrP(C)) that involves a conformational change after LLPS and is regulated by mutations and poly(4-styrenesulfonic acid-co-maleic acid) (PSCMA), a molecule that has been reported to rescue Alzhei …
Here, we report on a maturation process for the cellular prion protein (PrP(C)) that involves a conformational change after LLPS and is regu …
Torsemide Crystalline Salts with a Significant Spring-Parachute Effect.
Deng X, Shi W, Qian K, Yang J, Yuan S, Li H. Deng X, et al. AAPS PharmSciTech. 2024 Sep 7;25(7):210. doi: 10.1208/s12249-024-02926-3. AAPS PharmSciTech. 2024. PMID: 39242368
Cocrystallization with organic acids is an effective way to improve its solubility. Here, we reported maleate and phthalate of torsemide, in which the organic acid lost a proton transferring to the pyridine of torsemide, and torsemide interacted with organic acid through N …
Cocrystallization with organic acids is an effective way to improve its solubility. Here, we reported maleate and phthalate of torsem …
A theoretical study of the effect of a tetraalkylammonium counterion on the hydrogen bond strength in Z-hydrogen maleate.
Bach RD, Dmitrenko O, Glukhovtsev MN. Bach RD, et al. J Am Chem Soc. 2001 Jul 25;123(29):7134-45. doi: 10.1021/ja010362m. J Am Chem Soc. 2001. PMID: 11459494
High-level ab initio calculations (B3LYP/6-31+G and QCISD(T)/6-311+G**) were carried out to resolve the disagreement between recent experimental and computational estimates of the relative strength of the intramolecular hydrogen bond in Z-hydrogen maleate anion with respec …
High-level ab initio calculations (B3LYP/6-31+G and QCISD(T)/6-311+G**) were carried out to resolve the disagreement between recent experime …
An Oncometabolite Isomer Rapidly Induces a Pathophysiological Protein Modification.
Bergholtz SE, Briney CA, Najera SS, Perez M, Linehan WM, Meier JL. Bergholtz SE, et al. ACS Chem Biol. 2020 Apr 17;15(4):856-861. doi: 10.1021/acschembio.0c00044. Epub 2020 Apr 6. ACS Chem Biol. 2020. PMID: 32250583 Free PMC article.
Using a combination of antibody-based detection and kinetic assays, we benchmark the in vitro and cellular reactivity of two novel S-succination "agonists," maleate and 2-bromosuccinate. Cellular assays reveal maleate to be a more potent and less toxic inducer of S- …
Using a combination of antibody-based detection and kinetic assays, we benchmark the in vitro and cellular reactivity of two novel S-succina …
Extending the shikimate pathway for microbial production of maleate from glycerol in engineered Escherichia coli.
Sheng H, Jing Y, An N, Shen X, Sun X, Yan Y, Wang J, Yuan Q. Sheng H, et al. Biotechnol Bioeng. 2021 May;118(5):1840-1850. doi: 10.1002/bit.27700. Epub 2021 Feb 4. Biotechnol Bioeng. 2021. PMID: 33512000
Subsequent scale-up biosynthesis of maleate in a 3-L bioreactor under fed-batch culture conditions enabled the production of 14.5 g/L of maleate, indicating a 268-fold improvement compared with the titer generated by the wildtype E. coli strain carrying the entire …
Subsequent scale-up biosynthesis of maleate in a 3-L bioreactor under fed-batch culture conditions enabled the production of 14.5 g/L …
Negative chemotaxis of Ralstonia pseudosolanacearum to maleate and identification of the maleate chemosensory protein.
Tunchai M, Hida A, Oku S, Nakashimada Y, Nikata T, Tajima T, Kato J. Tunchai M, et al. J Biosci Bioeng. 2017 Dec;124(6):647-652. doi: 10.1016/j.jbiosc.2017.07.002. Epub 2017 Jul 23. J Biosci Bioeng. 2017. PMID: 28743655
Interestingly, the mcpP-deletion mutant was attracted to maleate, indicating that this bacterium expresses a MCP(s) for both positive and negative chemotaxis to maleate. ...Introduction of a plasmid harboring the mcpP gene (pPS16) restored the ability to negatively …
Interestingly, the mcpP-deletion mutant was attracted to maleate, indicating that this bacterium expresses a MCP(s) for both positive …
A comparison of high-throughput plasma NMR protocols for comparative untargeted metabolomics.
Bliziotis NG, Engelke UFH, Aspers RLEG, Engel J, Deinum J, Timmers HJLM, Wevers RA, Kluijtmans LAJ. Bliziotis NG, et al. Metabolomics. 2020 May 1;16(5):64. doi: 10.1007/s11306-020-01686-y. Metabolomics. 2020. PMID: 32358672 Free PMC article.
METHODS: We compared the conventional CPMG approach to a novel procedure that involves diffusion NMR, using the Longitudinal Eddy-Current Delay (LED) experiment, maleic acid (MA) as the quantification reference and peak picking for spectral reduction. ...
METHODS: We compared the conventional CPMG approach to a novel procedure that involves diffusion NMR, using the Longitudinal Eddy-Current De …
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