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Review
. 2018 Mar;23(2):237-253.
doi: 10.1007/s10741-018-9683-2.

Redefining biomarkers in heart failure

Michele Correale  1 , Ilenia Monaco  2 , Natale Daniele Brunetti  2 , Matteo Di Biase  2 , Marco Metra  3 , Savina Nodari  3 , Javed Butler  4 , Mihi Gheorghiade  5 ; Master Program Students on Drug Development for Heart Failure
Affiliations
Review

Redefining biomarkers in heart failure

Michele Correale et al. Heart Fail Rev. 2018 Mar.

Abstract

Heart failure (HF) is the end result of many different cardiac and non-cardiac abnormalities leading to a complex clinical entity. In this view, the use of biomarkers in HF should be deeply reconsidered; indeed, the same biomarker may carry a different significance in patients with preserved or reduced EF. The aim of this review is to reconsider the role of biomarkers in HF, based on the different clinical characteristics of this syndrome. The role of cardiac and non-cardiac biomarkers will be reviewed with respect of the different clinical manifestations of this syndrome.

Keywords: Biomarkers; Heart failure; Physiopathology; Preserved ejection fraction.

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