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74 results

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Page 1
The neurophysiological brain-fingerprint of Parkinson's disease.
da Silva Castanheira J, Wiesman AI, Hansen JY, Misic B, Baillet S; PREVENT-AD Research Group; Quebec Parkinson Network. da Silva Castanheira J, et al. EBioMedicine. 2024 Jul;105:105201. doi: 10.1016/j.ebiom.2024.105201. Epub 2024 Jun 21. EBioMedicine. 2024. PMID: 38908100 Free PMC article.
[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.
Pascoal TA, Chamoun M, Lax E, Wey HY, Shin M, Ng KP, Kang MS, Mathotaarachchi S, Benedet AL, Therriault J, Lussier FZ, Schroeder FA, DuBois JM, Hightower BG, Gilbert TM, Zürcher NR, Wang C, Hopewell R, Chakravarty M, Savard M, Thomas E, Mohaddes S, Farzin S, Salaciak A, Tullo S, Cuello AC, Soucy JP, Massarweh G, Hwang H, Kobayashi E, Hyman BT, Dickerson BC, Guiot MC, Szyf M, Gauthier S, Hooker JM, Rosa-Neto P. Pascoal TA, et al. Among authors: mathotaarachchi s. Nat Commun. 2022 Jul 19;13(1):4171. doi: 10.1038/s41467-022-30653-5. Nat Commun. 2022. PMID: 35853847 Free PMC article.
Harmonizing tau positron emission tomography in Alzheimer's disease: The CenTauR scale and the joint propagation model.
Leuzy A, Raket LL, Villemagne VL, Klein G, Tonietto M, Olafson E, Baker S, Saad ZS, Bullich S, Lopresti B, Bohorquez SS, Boada M, Betthauser TJ, Charil A, Collins EC, Collins JA, Cullen N, Gunn RN, Higuchi M, Hostetler E, Hutchison RM, Iaccarino L, Insel PS, Irizarry MC, Jack CR Jr, Jagust WJ, Johnson KA, Johnson SC, Karten Y, Marquié M, Mathotaarachchi S, Mintun MA, Ossenkoppele R, Pappas I, Petersen RC, Rabinovici GD, Rosa-Neto P, Schwarz CG, Smith R, Stephens AW, Whittington A, Carrillo MC, Pontecorvo MJ, Haeberlein SB, Dunn B, Kolb HC, Sivakumaran S, Rowe CC, Hansson O, Doré V. Leuzy A, et al. Among authors: mathotaarachchi s. Alzheimers Dement. 2024 Sep;20(9):5833-5848. doi: 10.1002/alz.13908. Epub 2024 Jul 23. Alzheimers Dement. 2024. PMID: 39041435 Free PMC article.
Hormone therapy is associated with lower Alzheimer's disease tau biomarkers in post-menopausal females -evidence from two independent cohorts.
Wang YT, Therriault J, Tissot C, Servaes S, Rahmouni N, Macedo AC, Fernandez-Arias J, Mathotaarachchi SS, Stevenson J, Lussier FZ, Benedet AL, Pascoal TA, Ashton NJ, Zetterberg H, Blennow K, Gauthier S, Rosa-Neto P. Wang YT, et al. Among authors: mathotaarachchi ss. Alzheimers Res Ther. 2024 Jul 22;16(1):162. doi: 10.1186/s13195-024-01509-5. Alzheimers Res Ther. 2024. PMID: 39034389 Free PMC article.
Microglial activation and tau propagate jointly across Braak stages.
Pascoal TA, Benedet AL, Ashton NJ, Kang MS, Therriault J, Chamoun M, Savard M, Lussier FZ, Tissot C, Karikari TK, Ottoy J, Mathotaarachchi S, Stevenson J, Massarweh G, Schöll M, de Leon MJ, Soucy JP, Edison P, Blennow K, Zetterberg H, Gauthier S, Rosa-Neto P. Pascoal TA, et al. Among authors: mathotaarachchi s. Nat Med. 2021 Sep;27(9):1592-1599. doi: 10.1038/s41591-021-01456-w. Epub 2021 Aug 26. Nat Med. 2021. PMID: 34446931
Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity.
Moscoso A, Heeman F, Raghavan S, Costoya-Sánchez A, van Essen M, Mainta I, Camacho V, Rodríguez-Fonseca O, Silva-Rodríguez J, Perissinotti A, Gu Y, Yun J, Peretti D, Ribaldi F, Coomans EM, Brum WS, Grothe MJ, Aguiar P, Bischof GN, Drzezga A, Seo SW, Villeneuve S, Malpetti M, O'Brien JT, Rowe JB, van de Giessen EM, Ossenkoppele R, Jagust WJ, Smith R, Hansson O, Frisoni GB, Garibotto V, Soleimani-Meigooni DN, Carrillo M, Dickerson BC, La Joie R, Rabinovici GD, Apostolova LG, LaMontagne PJ, Pontecorvo MJ, Johnson KA, Sperling RA, Weiner MW, Petersen RC, Jack CR Jr, Vemuri P, Schöll M; PREVENT-AD Research Group, the Harvard Aging Brain Study, the LEADS Consortium, and the Alzheimer’s Disease Neuroimaging Initiative. Moscoso A, et al. JAMA. 2025 Jul 15;334(3):229-242. doi: 10.1001/jama.2025.7817. JAMA. 2025. PMID: 40522652
Tau profiling across Alzheimer's disease staging reveals vulnerability to disease pathophysiology.
Bezgin G, Pascoal TA, Therriault J, Lussier FZ, Servaes S, Kang MS, Savard M, Tissot C, Stevenson J, Wang YT, Ottoy J, Rahmouni N, Fernandez-Arias J, Hosseini SA, Aumont É, Hall B, Poltronetti NM, Pallen V, Benedet AL, Ashton NJ, Blennow K, Zetterberg H, Karikari TK, Terada T, Chamoun M, Mathotaarachchi S, Macedo AC, Stevenson A, Kunach P, Massarweh G, Vitali P, Soucy JP, Iturria-Medina Y, Gauthier S, Rosa-Neto P. Bezgin G, et al. Among authors: mathotaarachchi s. Eur J Nucl Med Mol Imaging. 2025 Sep;52(11):4281-4291. doi: 10.1007/s00259-025-07257-4. Epub 2025 Apr 25. Eur J Nucl Med Mol Imaging. 2025. PMID: 40274672 Free PMC article.
Plasma phosphorylated tau217 strongly associates with memory deficits in the Alzheimer's disease spectrum.
Fernández Arias J, Brum WS, Salvadó G, Therriault J, Servaes S, Wang YT, Aumont E, Rahmouni N, Macedo AC, Quispialaya KM, Hosseini SA, Kunach P, Jia WL, Chan T, Trudel L, Hall B, Zheng Y, Mohapatra S, Mathotaarachchi SS, Vitali P, Tissot C, Bezgin G, Iturria-Medina Y, Ashton NJ, Benedet AL, Karikari TK, Triana-Baltzer G, Klostranec JM, Kolb HC, Zimmer ER, Janelidze S, Mattsson-Carlgren N, Stomrud E, Palmqvist S, Zetterberg H, Blennow K, Pascoal T, Montembeault M, Hansson O, Rosa-Neto P. Fernández Arias J, et al. Among authors: mathotaarachchi ss. Brain. 2025 Jul 7;148(7):2384-2399. doi: 10.1093/brain/awaf033. Brain. 2025. PMID: 39879633 Free PMC article.
Identify biological Alzheimer's disease using a novel nucleic acid-linked protein immunoassay.
Wang YT, Ashton NJ, Therriault J, Benedet AL, Macedo AC, Pola I, Aumont E, Di Molfetta G, Fernandez-Arias J, Tan K, Rahmouni N, Servaes SJG, Isaacson R, Chan T, Hosseini SA, Tissot C, Mathotaarachchi S, Stevenson J, Lussier FZ, Pascoal TA, Gauthier S, Blennow K, Zetterberg H, Rosa-Neto P. Wang YT, et al. Among authors: mathotaarachchi s. Brain Commun. 2025 Jan 7;7(1):fcaf004. doi: 10.1093/braincomms/fcaf004. eCollection 2025. Brain Commun. 2025. PMID: 39845736 Free PMC article.
74 results