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A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration.
D'Ignazio L, Lorenzetti APR, Penney EB, Evans TA, Qamar B, McCord AE, Feltrin AS, Barbosa AR, Sheehan BJ, Araujo B, Giles HH, Wang Y, Sawada T, Zabolocki M, Murcar M, Fernandez-Cerado C, Legarda GP, Sy M, Velasco-Andrada MS, Munoz E, Ang MC, Diesta CCE, Bardy C, Bragg DC, Paquola ACM, Erwin JA. D'Ignazio L, et al. Among authors: mccord ae. Cell Rep. 2025 Jul 22;44(7):115812. doi: 10.1016/j.celrep.2025.115812. Epub 2025 Jun 19. Cell Rep. 2025. PMID: 40540399 Free article.
Recapitulation of Perturbed Striatal Gene Expression Dynamics of Donors' Brains With Ventral Forebrain Organoids Derived From the Same Individuals With Schizophrenia.
Sawada T, Barbosa AR, Araujo B, McCord AE, D'Ignazio L, Benjamin KJM, Sheehan B, Zabolocki M, Feltrin A, Arora R, Brandtjen AC, Kleinman JE, Hyde TM, Bardy C, Weinberger DR, Paquola ACM, Erwin JA. Sawada T, et al. Among authors: mccord ae. Am J Psychiatry. 2024 Jun 1;181(6):493-511. doi: 10.1176/appi.ajp.20220723. Epub 2023 Nov 2. Am J Psychiatry. 2024. PMID: 37915216 Free PMC article.
62 results