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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 3
1992 4
1993 5
1994 4
1995 2
1996 1
1998 5
1999 4
2000 8
2001 4
2002 8
2003 5
2004 9
2005 11
2006 11
2007 7
2008 10
2009 11
2010 17
2011 18
2012 9
2013 15
2014 16
2015 9
2016 15
2017 10
2018 10
2019 7
2020 6
2021 13
2022 8
2023 4
2024 7
2025 5

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262 results

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Page 1
Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity.
Vennin C, Cattaneo CM, Bosch L, Vegna S, Ma X, Damstra HGJ, Martinovic M, Tsouri E, Ilic M, Azarang L, van Weering JRT, Pulver E, Zeeman AL, Schelfhorst T, Lohuis JO, Rios AC, Dekkers JF, Akkari L, Menezes R, Medema R, Baglio SR, Akhmanova A, Linn SC, Lemeer S, Pegtel DM, Voest EE, van Rheenen J. Vennin C, et al. Among authors: medema r. Cancer Cell. 2023 Jun 12;41(6):1170-1185.e12. doi: 10.1016/j.ccell.2023.05.009. Cancer Cell. 2023. PMID: 37311414 Free article.
Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy.
Dias MH, Friskes A, Wang S, Fernandes Neto JM, van Gemert F, Mourragui S, Papagianni C, Kuiken HJ, Mainardi S, Alvarez-Villanueva D, Lieftink C, Morris B, Dekker A, van Dijk E, Wilms LHS, da Silva MS, Jansen RA, Mulero-Sánchez A, Malzer E, Vidal A, Santos C, Salazar R, Wailemann RAM, Torres TEP, De Conti G, Raaijmakers JA, Snaebjornsson P, Yuan S, Qin W, Kovach JS, Armelin HA, Te Riele H, van Oudenaarden A, Jin H, Beijersbergen RL, Villanueva A, Medema RH, Bernards R. Dias MH, et al. Among authors: medema rh. Cancer Discov. 2024 Jul 1;14(7):1276-1301. doi: 10.1158/2159-8290.CD-23-0216. Cancer Discov. 2024. PMID: 38533987 Free PMC article.
Oncogene Silencing via ecDNA Micronucleation.
Brückner L, Xu R, Tang J, Herrmann A, Wong IT, Zhang S, Tu F, Pilon M, Kukalev A, Pardon K, Sidorova O, Atta J, Yu Q, Pradella D, Ilić M, Marco-Novais-Cruz, Kaltenbach S, Treue D, Giurgiu M, Herzog S, Hollinger AS, Fernandez M, Becker F, Louma VR, Schmargon R, Dörr J, Gamlin D, Lehmann A, Gürgen D, Richter M, Dubois F, Simeoni F, Pennycook BR, Hamilton A, Lindemann RK, Fischer M, Bafna V, Wahl G, Koche RP, Chang HY, Papathanasiou S, Medema R, Spanjaard B, Ventura A, Pombo A, Huang W, Werner B, Mischel PS, Henssen AG. Brückner L, et al. Among authors: medema r. bioRxiv [Preprint]. 2025 Apr 18:2025.04.15.648906. doi: 10.1101/2025.04.15.648906. bioRxiv. 2025. PMID: 40321211 Free PMC article. Preprint.
Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence.
Linder S, Hoogstraat M, Stelloo S, Eickhoff N, Schuurman K, de Barros H, Alkemade M, Bekers EM, Severson TM, Sanders J, Huang CF, Morova T, Altintas UB, Hoekman L, Kim Y, Baca SC, Sjöström M, Zaalberg A, Hintzen DC, de Jong J, Kluin RJC, de Rink I, Giambartolomei C, Seo JH, Pasaniuc B, Altelaar M, Medema RH, Feng FY, Zoubeidi A, Freedman ML, Wessels LFA, Butler LM, Lack NA, van der Poel H, Bergman AM, Zwart W. Linder S, et al. Among authors: medema rh. Cancer Discov. 2022 Sep 2;12(9):2074-2097. doi: 10.1158/2159-8290.CD-21-0576. Cancer Discov. 2022. PMID: 35754340 Free PMC article.
Perturbations in 3D genome organization can promote acquired drug resistance.
Manjón AG, Manzo SG, Prekovic S, Potgeter L, van Schaik T, Liu NQ, Flach K, Peric-Hupkes D, Joosten S, Teunissen H, Friskes A, Ilic M, Hintzen D, Franceschini-Santos VH, Zwart W, de Wit E, van Steensel B, Medema RH. Manjón AG, et al. Among authors: medema rh. Cell Rep. 2023 Oct 31;42(10):113124. doi: 10.1016/j.celrep.2023.113124. Epub 2023 Sep 20. Cell Rep. 2023. PMID: 37733591 Free article.
Cytokinesis defects and cancer.
Lens SMA, Medema RH. Lens SMA, et al. Among authors: medema rh. Nat Rev Cancer. 2019 Jan;19(1):32-45. doi: 10.1038/s41568-018-0084-6. Nat Rev Cancer. 2019. PMID: 30523339 Review.
A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer.
Rendo V, Schubert M, Khuu N, Suarez Peredo Rodriguez MF, Whyte D, Ling X, van den Brink A, Huang K, Swift M, He Y, Zerbib J, Smith R, Raaijmakers J, Bandopadhayay P, Guenther LM, Hwang JH, Iniguez A, Moody S, Seo JH, Stover EH, Garraway L, Hahn WC, Stegmaier K, Medema RH, Chowdhury D, Colomé-Tatché M, Ben-David U, Beroukhim R, Foijer F. Rendo V, et al. Among authors: medema rh. Nat Commun. 2025 Jan 27;16(1):1077. doi: 10.1038/s41467-025-56301-2. Nat Commun. 2025. PMID: 39870664 Free PMC article.
SRBD1, a highly conserved gene required for chromosome individualization.
Raaijmakers JA, Janssen LME, Mazouzi A, Hondema ALH, Borza R, Fish A, Elbatsh AMO, Kazokaitė-Adomaitienė J, Vaquero-Siguero N, Mayayo-Peralta I, Nahidiazar L, Friskes A, Hoekman L, Bleijerveld OB, Hoencamp C, Moser SC, Jonkers J, Jalink K, Zwart W, Celie PHN, Rowland BD, Perrakis A, Brummelkamp TR, Medema RH. Raaijmakers JA, et al. Among authors: medema rh. Cell Rep. 2025 Apr 22;44(4):115443. doi: 10.1016/j.celrep.2025.115443. Epub 2025 Mar 18. Cell Rep. 2025. PMID: 40106440 Free article.
Life of double minutes: generation, maintenance, and elimination.
Ilić M, Zaalberg IC, Raaijmakers JA, Medema RH. Ilić M, et al. Among authors: medema rh. Chromosoma. 2022 Sep;131(3):107-125. doi: 10.1007/s00412-022-00773-4. Epub 2022 Apr 30. Chromosoma. 2022. PMID: 35487993 Free PMC article. Review.
262 results