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1959 4
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1974 1
1975 6
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4,402 results

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Page 1
The molecular biology of NF2/Merlin on tumorigenesis and development.
Vlashi R, Sun F, Zheng C, Zhang X, Liu J, Chen G. Vlashi R, et al. FASEB J. 2024 Jul 15;38(13):e23809. doi: 10.1096/fj.202400019RR. FASEB J. 2024. PMID: 38967126 Review.
The neurofibromatosis type 2 (NF2) gene, known for encoding the tumor suppressor protein Merlin, is central to the study of tumorigenesis and associated cellular processes. This review comprehensively examines the multifaceted role of NF2/Merlin, detailing its struc …
The neurofibromatosis type 2 (NF2) gene, known for encoding the tumor suppressor protein Merlin, is central to the study of tumorigen …
Shedding light on Merlin's wizardry.
Okada T, You L, Giancotti FG. Okada T, et al. Trends Cell Biol. 2007 May;17(5):222-9. doi: 10.1016/j.tcb.2007.03.006. Epub 2007 Apr 17. Trends Cell Biol. 2007. PMID: 17442573 Review.
Merlin is an Ezrin-Radixin-Moesin protein and localizes underneath the plasma membrane at cell-cell junctions and other actin-rich sites. ...Here, we review these recent findings and their relevance to the tumor suppressor function of Merlin....
Merlin is an Ezrin-Radixin-Moesin protein and localizes underneath the plasma membrane at cell-cell junctions and other actin-rich si …
Merlin's wizardry guides cohesive migration.
Zoch A, Morrison H. Zoch A, et al. Nat Cell Biol. 2015 Mar;17(3):212-3. doi: 10.1038/ncb3126. Nat Cell Biol. 2015. PMID: 25720961
The collective migration of epithelial cell sheets is now shown to be mediated by a signalling axis that involves the merlin tumour-suppressor protein, the tight-junction-associated angiomotin-Rich1 complex and the Rac1 small GTPase....
The collective migration of epithelial cell sheets is now shown to be mediated by a signalling axis that involves the merlin tumour-s …
Neurofibromatosis 2: loss of merlin's protective spell.
Gusella JF, Ramesh V, MacCollin M, Jacoby LB. Gusella JF, et al. Curr Opin Genet Dev. 1996 Feb;6(1):87-92. doi: 10.1016/s0959-437x(96)90016-7. Curr Opin Genet Dev. 1996. PMID: 8791482 Review.
In 1993, a location cloning approach revealed this tumor suppressor, dubbed merlin, as a novel member of a family of proteins that link elements of the cytoskeleton and the cell membrane. Subsequent investigations have confirmed merlin's role in tumor formati …
In 1993, a location cloning approach revealed this tumor suppressor, dubbed merlin, as a novel member of a family of proteins that li …
Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling.
Wu J, Minikes AM, Gao M, Bian H, Li Y, Stockwell BR, Chen ZN, Jiang X. Wu J, et al. Nature. 2019 Aug;572(7769):402-406. doi: 10.1038/s41586-019-1426-6. Epub 2019 Jul 24. Nature. 2019. PMID: 31341276 Free PMC article.
In epithelial cells, such interactions mediated by E-cadherin suppress ferroptosis by activating the intracellular NF2 (also known as merlin) and Hippo signalling pathway. Antagonizing this signalling axis allows the proto-oncogenic transcriptional co-activator YAP to prom …
In epithelial cells, such interactions mediated by E-cadherin suppress ferroptosis by activating the intracellular NF2 (also known as mer …
Merlin's maestro.
Fletcher L. Fletcher L. Nat Biotechnol. 2002 Jul;20 Suppl:BE13-4. doi: 10.1038/nbt0602supp-BE13. Nat Biotechnol. 2002. PMID: 12089571 No abstract available.
Merlin's molars.
Ladd GA. Ladd GA. CAL. 1986 Jun;49(12):14-5, 31. CAL. 1986. PMID: 3460677 No abstract available.
Phylogeny of Merlin's grass (Isoetaceae): revealing an "Amborella syndrome" and the importance of geographic distribution for understanding current and historical diversity.
Larsén E, Wikström N, Khodabandeh A, Rydin C. Larsén E, et al. BMC Ecol Evol. 2022 Mar 16;22(1):32. doi: 10.1186/s12862-022-01988-w. BMC Ecol Evol. 2022. PMID: 35296231 Free PMC article.
BACKGROUND: Merlin's grass (Isoetes, Isoetaceae, Lycopsida), is the extant remnant of the isoetalean wood-producing lycopsids that originated during the Paleozoic, possibly in aquatic or boggy habitats. ...
BACKGROUND: Merlin's grass (Isoetes, Isoetaceae, Lycopsida), is the extant remnant of the isoetalean wood-producing lycopsids …
Merlin's 'invalid or gouty chair' and the origin of the self-propelled wheelchair.
Weiner MF, Silver JR. Weiner MF, et al. J Med Biogr. 2016 Aug;24(3):412-7. doi: 10.1177/0967772015584738. Epub 2015 May 29. J Med Biogr. 2016. PMID: 26025852
The first self-propelled wheelchair has been attributed to John Joseph Merlin, the 'ingenious mechanick', in the early 19th century and his 'gouty chair' is exhibited at Kenwood House. Research would suggest that comparable chairs existed in France as early as 1751 and the …
The first self-propelled wheelchair has been attributed to John Joseph Merlin, the 'ingenious mechanick', in the early 19th century a …
4,402 results