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Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trials.
Mayer-Hamblett N, Ratjen F, Russell R, Donaldson SH, Riekert KA, Sawicki GS, Odem-Davis K, Young JK, Rosenbluth D, Taylor-Cousar JL, Goss CH, Retsch-Bogart G, Clancy JP, Genatossio A, O'Sullivan BP, Berlinski A, Millard SL, Omlor G, Wyatt CA, Moffett K, Nichols DP, Gifford AH; SIMPLIFY Study Group. Mayer-Hamblett N, et al. Lancet Respir Med. 2023 Apr;11(4):329-340. doi: 10.1016/S2213-2600(22)00434-9. Epub 2022 Nov 4. Lancet Respir Med. 2023. PMID: 36343646 Free PMC article. Clinical Trial.
Trial design of bacteriophage therapy for nontuberculous mycobacteria pulmonary disease in cystic fibrosis: The POSTSTAMP study.
Nick JA, Martiniano SL, Lovell VK, Vestal B, Poch K, Caceres SM, Rysavy NM, de Moura VC, Gilick JJ, Malcolm KC, Pacheco J, Amin AG, Chatterjee D, Daley CL, Kasperbauer S, Gross JE, Armantrout E, Cohen KA, Keck A, Vandalfsen JM, Magaret AS, Midamba N, Chapdu C, Gao A, Hill JE, Freeman KG, Cristinziano M, Guerrero C, Jacobs-Sera D, Lauer MJ, Viland M, Hatfull GF; Investigators of the Cystic Fibrosis NTM Consortium. Nick JA, et al. Among authors: midamba n. J Cyst Fibros. 2025 Jul;24(4):684-690. doi: 10.1016/j.jcf.2025.03.669. Epub 2025 Apr 12. J Cyst Fibros. 2025. PMID: 40222858 Free article.