A tripartite organelle platform links growth factor receptor signaling to mitochondrial metabolism.
Mesa D, Barbieri E, Raimondi A, Freddi S, Miloro G, Jendrisek G, Caldieri G, Quarto M, Schiano Lomoriello I, Malabarba MG, Bresci A, Manetti F, Vernuccio F, Abdo H, Scita G, Lanzetti L, Polli D, Tacchetti C, Pinton P, Bonora M, Di Fiore PP, Sigismund S.
Mesa D, et al.
Nat Commun. 2024 Jun 15;15(1):5119. doi: 10.1038/s41467-024-49543-z.
Nat Commun. 2024.
PMID: 38879572
Free PMC article.
The multiorganelle signaling platform herein described mediates direct communication between EGFR signaling and mitochondrial metabolism, and is predicted to have a broad impact on cell physiology as it is activated by another growth factor receptor, HGFR/MET....
The multiorganelle signaling platform herein described mediates direct communication between EGFR signaling and mitochondrial metabolism, an …