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Year Number of Results
1964 1
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1969 2
1970 2
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1973 5
1974 10
1975 2
1976 8
1977 7
1978 16
1979 22
1980 36
1981 57
1982 82
1983 124
1984 169
1985 199
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1987 282
1988 304
1989 394
1990 436
1991 452
1992 518
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1994 564
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1997 613
1998 591
1999 644
2000 772
2001 762
2002 723
2003 692
2004 736
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2007 824
2008 813
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2011 25
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2015 3
2017 2
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15,162 results

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Page 1
Showing results for microm o
Search for Miro MO instead (1 results)
Characterization of a nucleolar 2'-O-methyltransferase and its involvement in the methylation of mouse precursor ribosomal RNA.
Eichler DC. Eichler DC. Biochimie. 1994;76(12):1115-22. doi: 10.1016/0300-9084(94)90039-6. Biochimie. 1994. PMID: 7748946 Review.
A nucleolar 2'-O-methyltransferase, partially purified from isolated mouse nucleoli, catalyzes the methylation of each of the four nucleosides, although to different levels depending on the RNA substrate. Similar to most methyltransferases which use S-adenosyl-L-methionine …
A nucleolar 2'-O-methyltransferase, partially purified from isolated mouse nucleoli, catalyzes the methylation of each of the four nu …
Resistance-modifying agents. 8. Inhibition of O(6)-alkylguanine-DNA alkyltransferase by O(6)-alkenyl-, O(6)-cycloalkenyl-, and O(6)-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O(6)-(1-cyclopentenylmethyl)guanine.
Griffin RJ, Arris CE, Bleasdale C, Boyle FT, Calvert AH, Curtin NJ, Dalby C, Kanugula S, Lembicz NK, Newell DR, Pegg AE, Golding BT. Griffin RJ, et al. J Med Chem. 2000 Nov 2;43(22):4071-83. doi: 10.1021/jm000961o. J Med Chem. 2000. PMID: 11063604
Simple O(6)-alkyl- and O(6)-cycloalkylguanines were weak AGT inactivators compared with O(6)-allylguanine (IC(50) = 8.5 +/- 0.6 microM) with IC(50) values ranging from 100 to 1000 microM. The introduction of substituents at C-2 of the allyl grou …
Simple O(6)-alkyl- and O(6)-cycloalkylguanines were weak AGT inactivators compared with O(6)-allylguanine (IC(50) = 8.5 …
O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.
Macauley MS, Whitworth GE, Debowski AW, Chin D, Vocadlo DJ. Macauley MS, et al. J Biol Chem. 2005 Jul 8;280(27):25313-22. doi: 10.1074/jbc.M413819200. Epub 2005 Mar 28. J Biol Chem. 2005. PMID: 15795231 Free article.
The post-translational modification of serine and threonine residues of nucleocytoplasmic proteins with 2-acetamido-2-deoxy-d-glucopyranose (GlcNAc) is a reversible process implicated in multiple cellular processes. The enzyme O-GlcNAcase catalyzes the cleavage of beta- …
The post-translational modification of serine and threonine residues of nucleocytoplasmic proteins with 2-acetamido-2-deoxy-d-glucopyranose …
Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.
Chen M, LeDuc B, Kerr S, Howe D, Williams DA. Chen M, et al. Drug Metab Dispos. 2010 Mar;38(3):368-75. doi: 10.1124/dmd.109.029900. Epub 2009 Dec 11. Drug Metab Dispos. 2010. PMID: 20008037
The formation of 1-O-CP glucuronide by pooled HLM and expressed UGT2B7 exhibited substrate inhibition kinetics with apparent K(m) values of 408.2 and 115.0 microM, respectively. Azidothymidine (AZT) and hyodeoxycholic acid (substrates of UGT2B7) inhibited 3-O …
The formation of 1-O-CP glucuronide by pooled HLM and expressed UGT2B7 exhibited substrate inhibition kinetics with apparent K(m) val …
DNA sensor for o-dianisidine.
Jasnowska J, Ligaj M, Stupnicka B, Filipiak M. Jasnowska J, et al. Bioelectrochemistry. 2004 Aug;64(1):85-90. doi: 10.1016/j.bioelechem.2004.03.004. Bioelectrochemistry. 2004. PMID: 15219251
o-Dianisidine (3,3'-dimethoxybenzidine) is applied in the production of some dyes and also used in analytical tests. ...Initial reduction of guanine peak took place already at the concentration of o-dianisidine equal to 0.4 microM; high concentrations (above …
o-Dianisidine (3,3'-dimethoxybenzidine) is applied in the production of some dyes and also used in analytical tests. ...Initial reduc …
Potentiation of temozolomide and BCNU cytotoxicity by O(6)-benzylguanine: a comparative study in vitro.
Wedge SR, Porteus JK, May BL, Newlands ES. Wedge SR, et al. Br J Cancer. 1996 Feb;73(4):482-90. doi: 10.1038/bjc.1996.85. Br J Cancer. 1996. PMID: 8595163 Free PMC article.
In multiple dosing studies two colorectal cell lines (Mawi and LS174T) were treated with temozolomide or BCNU at 24 h intervals for up to 5 days, with or without either 100 microM O(6)-BG for 1 h or 1 microM O(6)-BG for 24 h, commencing 1 h before alky …
In multiple dosing studies two colorectal cell lines (Mawi and LS174T) were treated with temozolomide or BCNU at 24 h intervals for up to 5 …
The photoreduction of H(2)O(2) by Synechococcus sp. PCC 7942 and UTEX 625.
Miller AG, Hunter KJ, O'Leary SJ, Hart LJ. Miller AG, et al. Plant Physiol. 2000 Jun;123(2):625-36. doi: 10.1104/pp.123.2.625. Plant Physiol. 2000. PMID: 10859192 Free PMC article.
PCC 7942 and UTEX 625. The addition of small amounts of H(2)O(2) (2.5 microM) to illuminated cells caused photochemical quenching (qP) of chlorophyll fluorescence that was relieved as the H(2)O(2) was consumed. The qP was maximal at about 50 microM H(2 …
PCC 7942 and UTEX 625. The addition of small amounts of H(2)O(2) (2.5 microM) to illuminated cells caused photochemical quench …
Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.
Yamanaka H, Nakajima M, Katoh M, Kanoh A, Tamura O, Ishibashi H, Yokoi T. Yamanaka H, et al. Drug Metab Dispos. 2005 Jan;33(1):23-30. doi: 10.1124/dmd.104.001701. Epub 2004 Oct 6. Drug Metab Dispos. 2005. PMID: 15470160
Trans-3'-hydroxycotinine O-glucuronosyltransferase activity in human liver microsomes was inhibited by imipramine (a substrate of UGT1A4, IC(50) = 55 microM), androstanediol (a substrate of UGT2B15, IC(50) = 169 microM), and propofol (a substrate of UGT1A9, I …
Trans-3'-hydroxycotinine O-glucuronosyltransferase activity in human liver microsomes was inhibited by imipramine (a substrate of UGT …
Sulfation of o-demethyl apixaban: enzyme identification and species comparison.
Wang L, Raghavan N, He K, Luettgen JM, Humphreys WG, Knabb RM, Pinto DJ, Zhang D. Wang L, et al. Drug Metab Dispos. 2009 Apr;37(4):802-8. doi: 10.1124/dmd.108.025593. Epub 2009 Jan 8. Drug Metab Dispos. 2009. PMID: 19131519
The aim of this study was to identify the sulfotransferases (SULTs) responsible for the sulfation reaction. Apixaban undergoes O-demethylation catalyzed by cytochrome P450 enzymes to O-demethyl apixaban, and then is conjugated by SULTs to form O-demethyl apix …
The aim of this study was to identify the sulfotransferases (SULTs) responsible for the sulfation reaction. Apixaban undergoes O-deme …
Heptachlor and o-p'DDT effects on protein kinase activities associated with human placenta particulate fractions.
Magnarelli G, Souza MS, de D'Angelo AM. Magnarelli G, et al. J Biochem Mol Toxicol. 2009 May-Jun;23(3):185-92. doi: 10.1002/jbt.20277. J Biochem Mol Toxicol. 2009. PMID: 19526567
In particulate fractions, total serine/threonine kinase activity was increased by 10 microM HC and o-p' DDT (59% and 82%, respectively). Maximum eightfold increase was observed with 10 microM o-p' DDT on protein kinase A activity. ...Exposition to 100 …
In particulate fractions, total serine/threonine kinase activity was increased by 10 microM HC and o-p' DDT (59% and 82%, resp …
15,162 results
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