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479 results

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Page 1
Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.
Belinsky MG, Bain LJ, Balsara BB, Testa JR, Kruh GD. Belinsky MG, et al. J Natl Cancer Inst. 1998 Nov 18;90(22):1735-41. doi: 10.1093/jnci/90.22.1735. J Natl Cancer Inst. 1998. PMID: 9827529
MOAT-D is also highly related to cMOAT (about 47% identity). The presence of an N-terminal membrane-spanning domain indicates that the topology of MOAT-D is quite similar to that of MRP and cMOAT. MOAT-C transcripts are widely expressed in human tissue …
MOAT-D is also highly related to cMOAT (about 47% identity). The presence of an N-terminal membrane-spanning domain indicates …
MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver.
Belinsky MG, Kruh GD. Belinsky MG, et al. Br J Cancer. 1999 Jul;80(9):1342-9. doi: 10.1038/sj.bjc.6690527. Br J Cancer. 1999. PMID: 10424734 Free PMC article.
We previously reported the isolation of three human MRP/cMOAT-related transporters, MOAT-B (MRP4), MOAT-C (MRP5) and MOAT-D (MRP3). In the present study we describe the fourth MRP/cMOAT-related transporter. ...MOAT-E encodes a 1503 residue transporter that is most c …
We previously reported the isolation of three human MRP/cMOAT-related transporters, MOAT-B (MRP4), MOAT-C (MRP5) and MOAT-D (M …
Drugs and hepatic transporters: A review.
Jetter A, Kullak-Ublick GA. Jetter A, et al. Pharmacol Res. 2020 Apr;154:104234. doi: 10.1016/j.phrs.2019.04.018. Epub 2019 Apr 17. Pharmacol Res. 2020. PMID: 31004787 Review.
The elimination of drugs and metabolites from the liver cell back to the bloodstream is accomplished mainly by multidrug resistance-associated protein 3 (MRP3) and MRP4, while the elimination towards the biliary canaliculi is mediated by several …
The elimination of drugs and metabolites from the liver cell back to the bloodstream is accomplished mainly by multidrug resistanc …
Sensitizing cholangiocarcinoma to chemotherapy by inhibition of the drug-export pump MRP3.
Asensio M, Briz O, Herraez E, Perez-Silva L, Espinosa-Escudero R, Bueno-Sacristan D, Peleteiro-Vigil A, Hammer H, Pötz O, Kadioglu O, Banales JM, Martinez-Chantar ML, Avila MA, Macias RIR, Efferth T, Marin JJG, Lozano E. Asensio M, et al. Biomed Pharmacother. 2024 Nov;180:117533. doi: 10.1016/j.biopha.2024.117533. Epub 2024 Oct 13. Biomed Pharmacother. 2024. PMID: 39405909 Free article.
Nomilin and its analogue obacunone alleviate NASH and hepatic fibrosis in mice via enhancing antioxidant and anti-inflammation capacity.
Han Y, Luo L, Li H, Zhang L, Yan Y, Fang M, Yu J, Gao X, Liu Y, Huang C, Fan S. Han Y, et al. Biofactors. 2023 Nov-Dec;49(6):1189-1204. doi: 10.1002/biof.1987. Epub 2023 Jul 4. Biofactors. 2023. PMID: 37401768
Additional, NML and OBA inhibited the expression of inflammatory gene interleukin 6 (Il-6), and regulated the bile acid metabolism genes Cyp3a11, Cyp7a1, multidrug resistance-associated protein 3 (Mrp3). Overall, these findings indicate that NML …
Additional, NML and OBA inhibited the expression of inflammatory gene interleukin 6 (Il-6), and regulated the bile acid metabolism genes Cyp …
Medical malpractice in hand surgery.
Pappas ND, Moat D, Lee DH. Pappas ND, et al. J Hand Surg Am. 2014 Jan;39(1):168-70. doi: 10.1016/j.jhsa.2013.06.021. J Hand Surg Am. 2014. PMID: 24369944 Review.
Multidrug resistance-associated protein 3 (Mrp3/Abcc3/Moat-D) is expressed in the SAE Squalus acanthias shark embryo-derived cell line.
Kobayashi H, Parton A, Czechanski A, Durkin C, Kong CC, Barnes D. Kobayashi H, et al. Zebrafish. 2007 Winter;4(4):261-75. doi: 10.1089/zeb.2007.0520. Zebrafish. 2007. PMID: 18284333 Free PMC article.
The multidrug resistance-associated protein 3 (MRP3/Mrp3) is a member of the ATP-binding cassette (ABC) protein family of membrane transporters and related proteins that act on a variety of xenobiotic and anionic molecules to transfer these subs …
The multidrug resistance-associated protein 3 (MRP3/Mrp3) is a member of the ATP-binding cassette (ABC) p …
Disease-associated comorbidities, medication records and anthropometric measures in adults with Duchenne muscular dystrophy.
Schiava M, Lofra RM, Bourke JP, James MK, Díaz-Manera J, Elseed MA, Michel-Sodhi J, Moat D, Mccallum M, Mayhew A, Ghimenton E, Díaz CFB, Malinova M, Wong K, Richardson M, Tasca G, Grover E, Robinson EJ, Tanner S, Eglon G, Behar L, Eagle M, Turner C, Verdú-Díaz J, Heslop E, Straub V, Bettolo CM, Guglieri M. Schiava M, et al. Neuromuscul Disord. 2024 Aug;41:8-19. doi: 10.1016/j.nmd.2024.05.007. Epub 2024 May 14. Neuromuscul Disord. 2024. PMID: 38865917
479 results