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Page 1
Showing results for mitzi s
Search for Moitzi S instead (1 results)
Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD): A Pilot Clinical Trial.
Gonzales MM, Garbarino VR, Marques Zilli E, Petersen RC, Kirkland JL, Tchkonia T, Musi N, Seshadri S, Craft S, Orr ME. Gonzales MM, et al. J Prev Alzheimers Dis. 2022;9(1):22-29. doi: 10.14283/jpad.2021.62. J Prev Alzheimers Dis. 2022. PMID: 35098970 Free PMC article. Clinical Trial.
Emerging evidence suggests that tau protein accumulation, which closely correlates with cognitive decline in Alzheimer's disease and other tauopathies, drives cellular senescence in the brain. Pharmacologically clearing senescent cells in mouse models of tauopathy reduced …
Emerging evidence suggests that tau protein accumulation, which closely correlates with cognitive decline in Alzheimer's disease and …
The Development of Ofatumumab, a Fully Human Anti-CD20 Monoclonal Antibody for Practical Use in Relapsing Multiple Sclerosis Treatment.
Hauser SL, Kappos L, Bar-Or A, Wiendl H, Paling D, Williams M, Gold R, Chan A, Milo R, Das Gupta A, Karlsson G, Sullivan R, Graham G, Merschhemke M, Häring DA, Vermersch P. Hauser SL, et al. Neurol Ther. 2023 Oct;12(5):1491-1515. doi: 10.1007/s40120-023-00518-0. Epub 2023 Jul 14. Neurol Ther. 2023. PMID: 37450172 Free PMC article. Review.
Rapamycin treatment for Alzheimer's disease and related dementias: a pilot phase 1 clinical trial.
Gonzales MM, Garbarino VR, Kautz TF, Song X, Lopez-Cruzan M, Linehan L, Van Skike CE, De Erausquin GA, Galvan V, Orr ME, Musi N, He Y, Bateman RJ, Wang CP, Seshadri S, Kraig E, Kellogg D Jr. Gonzales MM, et al. Commun Med (Lond). 2025 May 20;5(1):189. doi: 10.1038/s43856-025-00904-9. Commun Med (Lond). 2025. PMID: 40394335 Free PMC article.
BACKGROUND: Rapamycin has been shown to extend lifespan and acts on pathologies underlying Alzheimer's disease and related dementias in animal models. However, rapamycin's clinical application remains underexplored. ...The drug rapamycin has been shown to increase l …
BACKGROUND: Rapamycin has been shown to extend lifespan and acts on pathologies underlying Alzheimer's disease and related dementias …
The Clinical Nurse Specialist.
Saunders MM, Heiden G. Saunders MM, et al. Am J Nurs. 2023 Sep 1;123(9):19. doi: 10.1097/01.NAJ.0000978124.54571.fc. Am J Nurs. 2023. PMID: 37615461
Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer's disease.
Garbarino VR, Palavicini JP, Melendez J, Barthelemy NR, He Y, Kautz TF, Lopez-Cruzan M, Mathews JJ, Xu P, Zhang B, Saliba A, Ragi N, Sharma K, Mason D, Johnson S, Hendrix S, Craft S, Petersen RC, Espindola-Netto JM, Xue A, Tchkonia T, Kirkland JL, Salardini A, Musi N, Bateman RJ, Gonzales MM, Orr ME. Garbarino VR, et al. Neurotherapeutics. 2025 Jul;22(4):e00591. doi: 10.1016/j.neurot.2025.e00591. Epub 2025 Apr 23. Neurotherapeutics. 2025. PMID: 40274471 Free PMC article. Clinical Trial.
Senescent cell accumulation contributes to the progression of age-related disorders including Alzheimer's disease (AD). Clinical trials focused on cellular senescence are in early stages and have yet to establish reliable outcome measures reflecting senescent cell burden o …
Senescent cell accumulation contributes to the progression of age-related disorders including Alzheimer's disease (AD). Clinical tria …
Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study.
Salardini A, Himali JJ, Abdullah MS, Chaudhari R, Young V, Zilli EM, McGrath ER, Gonzales MM, Thibault EG, Salinas J, Aparicio HJ, Himali D, Ghosh S, Buckley RF, Satizabal CL, Johnson KA, DeCarli C, Fakhri GE, Vasan RS, Beiser AS, Seshadri S. Salardini A, et al. Alzheimers Dement. 2025 Apr;21(4):e70179. doi: 10.1002/alz.70179. Alzheimers Dement. 2025. PMID: 40271551 Free PMC article.
INTRODUCTION: This study investigates whether midlife cortisol levels predict Alzheimer's disease (AD) biomarker burden 15 years later, with particular attention to sex differences and menopausal status. ...Post-menopausal hormone changes may amplify cortisol's effe …
INTRODUCTION: This study investigates whether midlife cortisol levels predict Alzheimer's disease (AD) biomarker burden 15 years late …
Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium.
Quiroz YT, Solis M, Aranda MP, Arbaje AI, Arroyo-Miranda M, Cabrera LY, Carrasquillo MM, Corrada MM, Crivelli L, Diminich ED, Dorsman KA, Gonzales M, González HM, Gonzalez-Seda AL, Grinberg LT, Guerrero LR, Hill CV, Jimenez-Velazquez IZ, Guerra JJL, Lopera F, Maestre G, Medina LD, O'Bryant S, Peñaloza C, Pinzon MM, Mavarez RVP, Pluim CF, Raman R, Rascovsky K, Rentz DM, Reyes Y, Rosselli M, Tansey MG, Vila-Castelar C, Zuelsdorff M, Carrillo M, Sexton C. Quiroz YT, et al. Alzheimers Dement. 2022 Sep;18(9):1677-1686. doi: 10.1002/alz.12589. Epub 2022 Feb 24. Alzheimers Dement. 2022. PMID: 35199931 Free PMC article. Review.
The Alzheimer's Association hosted the second Latinos & Alzheimer's Symposium in May 2021. Due to the COVID-19 pandemic, the meeting was held online over 2 days, with virtual presentations, discussions, mentoring sessions, and posters. The Latino population in t …
The Alzheimer's Association hosted the second Latinos & Alzheimer's Symposium in May 2021. Due to the COVID-19 pandemic, t …
Chiral Cation Doping for Modulating Structural Symmetry of 2D Perovskites.
Xie Y, Morgenstein J, Bobay BG, Song R, Caturello NAMS, Sercel PC, Blum V, Mitzi DB. Xie Y, et al. J Am Chem Soc. 2023 Aug 16;145(32):17831-17844. doi: 10.1021/jacs.3c04832. Epub 2023 Aug 2. J Am Chem Soc. 2023. PMID: 37531203
Here, we demonstrate a chiral-chiral mixed-cation system wherein a controlled small amount (<10%) of chiral cation S-2-MeBA (S-2-MeBA = (S)-(-)-2-methylbutylammonium) can be doped into (S-BrMBA)(2)PbI(4) (S-BrMBA = (S)-(-)-4-bromo-alph …
Here, we demonstrate a chiral-chiral mixed-cation system wherein a controlled small amount (<10%) of chiral cation S-2-MeBA (S …
70 results