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Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trials.
Mayer-Hamblett N, Ratjen F, Russell R, Donaldson SH, Riekert KA, Sawicki GS, Odem-Davis K, Young JK, Rosenbluth D, Taylor-Cousar JL, Goss CH, Retsch-Bogart G, Clancy JP, Genatossio A, O'Sullivan BP, Berlinski A, Millard SL, Omlor G, Wyatt CA, Moffett K, Nichols DP, Gifford AH; SIMPLIFY Study Group. Mayer-Hamblett N, et al. Lancet Respir Med. 2023 Apr;11(4):329-340. doi: 10.1016/S2213-2600(22)00434-9. Epub 2022 Nov 4. Lancet Respir Med. 2023. PMID: 36343646 Free PMC article. Clinical Trial.
Vanzacaftor-tezacaftor-deutivacaftor versus elexacaftor-tezacaftor-ivacaftor in individuals with cystic fibrosis aged 12 years and older (SKYLINE Trials VX20-121-102 and VX20-121-103): results from two randomised, active-controlled, phase 3 trials.
Keating C, Yonker LM, Vermeulen F, Prais D, Linnemann RW, Trimble A, Kotsimbos T, Mermis J, Braun AT, O'Carroll M, Sutharsan S, Ramsey B, Mall MA, Taylor-Cousar JL, McKone EF, Tullis E, Floreth T, Michelson P, Sosnay PR, Nair N, Zahigian R, Martin H, Ahluwalia N, Lam A, Horsley A; VX20-121-102 Study Group; VX20-121-103 Study Group. Keating C, et al. Lancet Respir Med. 2025 Mar;13(3):256-271. doi: 10.1016/S2213-2600(24)00411-9. Epub 2025 Jan 2. Lancet Respir Med. 2025. PMID: 39756424 Free PMC article. Clinical Trial.
An alternative to petrochemicals: biomass electrovalorization.
Mukadam Z, Scott SB, Titirici MM, Stephens IEL. Mukadam Z, et al. Philos Trans A Math Phys Eng Sci. 2024 Nov 9;382(2282):20230262. doi: 10.1098/rsta.2023.0262. Epub 2024 Sep 23. Philos Trans A Math Phys Eng Sci. 2024. PMID: 39307165 Free PMC article. Review.
Unraveling the reaction mechanisms for furfural electroreduction on copper.
Liu S, Mukadam Z, Scott SB, Sarma SC, Titirici MM, Chan K, Govindarajan N, Stephens IEL, Kastlunger G. Liu S, et al. Among authors: mukadam z. EES Catal. 2023 Apr 28;1(4):539-551. doi: 10.1039/d3ey00040k. eCollection 2023 Jul 6. EES Catal. 2023. PMID: 37426696 Free PMC article.
Direct Electrosynthesis of an Amino Acid from a Biomass Derivative.
Mukadam Z, Liu S, Scott SB, Zhou Y, Kastlunger G, Ryan MP, Titirici MM, Stephens IEL. Mukadam Z, et al. ACS Electrochem. 2025 Mar 14;1(5):699-708. doi: 10.1021/acselectrochem.4c00171. eCollection 2025 May 1. ACS Electrochem. 2025. PMID: 40331008 Free PMC article.