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Page 1
MUTZ-3, a monocytic model cell line for interleukin-4 and lipopolysaccharide studies.
Quentmeier H, Duschl A, Hu ZB, Schnarr B, Zaborski M, Drexler HG. Quentmeier H, et al. Immunology. 1996 Dec;89(4):606-12. doi: 10.1046/j.1365-2567.1996.d01-780.x. Immunology. 1996. PMID: 9014829 Free PMC article.
The human monocytic cell lines MUTZ-3 and MONO-MAC-6 express the lipopolysaccharide (LPS) receptor CD14. Paralleling the situation in peripheral blood monocytes (PBMo), recombinant human interleukin-4 (IL-4) down-regulated the expression of CD14 on the cell surface of M
The human monocytic cell lines MUTZ-3 and MONO-MAC-6 express the lipopolysaccharide (LPS) receptor CD14. Paralleling the situation in …
MUTZ-3 derived Langerhans cells in human skin equivalents show differential migration and phenotypic plasticity after allergen or irritant exposure.
Kosten IJ, Spiekstra SW, de Gruijl TD, Gibbs S. Kosten IJ, et al. Toxicol Appl Pharmacol. 2015 Aug 15;287(1):35-42. doi: 10.1016/j.taap.2015.05.017. Epub 2015 May 29. Toxicol Appl Pharmacol. 2015. PMID: 26028481 Free article.
In this study we describe the unique ability of MUTZ-3 derived Langerhans cells (MUTZ-LC) to display similar phenotypic plasticity as their primary counterparts when incorporated into a physiologically relevant full-thickness skin equivalent model (SE-LC). ...The sk …
In this study we describe the unique ability of MUTZ-3 derived Langerhans cells (MUTZ-LC) to display similar phenotypic plasti …
MUTZ-3-derived dendritic cells as an in vitro alternative model to CD34+ progenitor-derived dendritic cells for testing of chemical sensitizers.
Nelissen I, Selderslaghs I, Heuvel RV, Witters H, Verheyen GR, Schoeters G. Nelissen I, et al. Toxicol In Vitro. 2009 Dec;23(8):1477-81. doi: 10.1016/j.tiv.2009.08.022. Epub 2009 Sep 2. Toxicol In Vitro. 2009. PMID: 19732821
The cytokine-dependent CD34(+) human acute myeloid leukaemia cell line MUTZ-3 was used to generate immature dendritic-like cells (MUTZ-3 DC) and their validity as an alternative to primary CD34(+) progenitor-derived DC (CD34-DC) for testing chemical-induced sensitiz …
The cytokine-dependent CD34(+) human acute myeloid leukaemia cell line MUTZ-3 was used to generate immature dendritic-like cells ( …
Integration of MUTZ-Langerhans cells into a 3D full-thickness skin equivalent and influences of serum reduction and undefined medium supplements on differentiation.
Böttcher P, Steinmeyer L, Stark H, Breitkreutz J, Mewes KR. Böttcher P, et al. Toxicol In Vitro. 2025 Jan;102:105948. doi: 10.1016/j.tiv.2024.105948. Epub 2024 Sep 27. Toxicol In Vitro. 2025. PMID: 39343070
However, MUTZ-3 cells must first be differentiated to achieve the LC-typical phenotype. As all protocols use high fetal calf serum (FCS) concentrations, we aimed at reducing, or even replacing FCS, while maintaining MUTZ-LC characteristics. ...Culture with Ultroser …
However, MUTZ-3 cells must first be differentiated to achieve the LC-typical phenotype. As all protocols use high fetal calf serum (F …
Transcriptome analysis.
Stahl F, Hitzmann B, Mutz K, Landgrebe D, Lübbecke M, Kasper C, Walter J, Scheper T. Stahl F, et al. Adv Biochem Eng Biotechnol. 2012;127:1-25. doi: 10.1007/10_2011_102. Adv Biochem Eng Biotechnol. 2012. PMID: 21952979 Review.
659 results