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Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial.
Chamorro A, Amaro S, Castellanos M, Segura T, Arenillas J, Martí-Fábregas J, Gállego J, Krupinski J, Gomis M, Cánovas D, Carné X, Deulofeu R, Román LS, Oleaga L, Torres F, Planas AM; URICO-ICTUS Investigators. Chamorro A, et al. Lancet Neurol. 2014 May;13(5):453-60. doi: 10.1016/S1474-4422(14)70054-7. Epub 2014 Apr 2. Lancet Neurol. 2014. PMID: 24703208 Clinical Trial.
Uric acid therapy improves the outcomes of stroke patients treated with intravenous tissue plasminogen activator and mechanical thrombectomy.
Chamorro Á, Amaro S, Castellanos M, Gomis M, Urra X, Blasco J, Arenillas JF, Román LS, Muñoz R, Macho J, Cánovas D, Marti-Fabregas J, Leira EC, Planas AM; URICO-ICTUS Investigators. Chamorro Á, et al. Int J Stroke. 2017 Jun;12(4):377-382. doi: 10.1177/1747493016684354. Epub 2016 Dec 20. Int J Stroke. 2017. PMID: 28345429 Clinical Trial.