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| Year | Number of Results | 
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| 2021 | 3 | 
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                Benefit-Risk Assessment of Esketamine Nasal Spray vs. Placebo in Treatment-Resistant Depression.
              
            
            
            
              
            
            
              
            
          
        
      
      
        
  
      
    
  
    
      
        
        
      
    
    
    Clin Pharmacol Ther. 2021 Feb;109(2):536-546. doi: 10.1002/cpt.2024. Epub 2020 Oct 13.
    Clin Pharmacol Ther. 2021.
  
  
  PMID: 32860422
  Free PMC article.
  
    
  
  Clinical Trial.
  
  
          
        
        
          
        
          
            
            
            
              
                Population Pharmacokinetics of Esketamine Nasal Spray and its Metabolite Noresketamine in Healthy Subjects and Patients with Treatment-Resistant Depression.
              
            
            
            
              
            
            
              
            
          
        
      
      
        
  
  
    
      
        Perez-Ruixo C, Rossenu S, Zannikos P, Nandy P, Singh J, Drevets WC, Perez-Ruixo JJ.
        
      
    
    Perez-Ruixo C, et al.
    Clin Pharmacokinet. 2021 Apr;60(4):501-516. doi: 10.1007/s40262-020-00953-4. Epub 2020 Oct 31.
    Clin Pharmacokinet. 2021.
  
  
  PMID: 33128208
  
  
    
  
  Clinical Trial.
  
  
          
        
        
          
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                Effect of Esketamine Nasal Spray on Olfactory Function and Nasal Tolerability in Patients with Treatment-Resistant Depression: Results from Four Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Studies.
              
            
            
            
              
            
            
              
            
          
        
      
      
        
  
  
    
      
        Doty RL, Popova V, Wylie C, Fedgchin M, Daly E, Janik A, Ochs-Ross R, Lane R, Lim P, Cooper K, Melkote R, Jamieson C, Singh J, Drevets WC.
        
      
    
    Doty RL, et al.
    CNS Drugs. 2021 Jul;35(7):781-794. doi: 10.1007/s40263-021-00826-9. Epub 2021 Jul 7.
    CNS Drugs. 2021.
  
  
  PMID: 34235612
  Free PMC article.
  
    
  
  Clinical Trial.
  
  
          
        
        
          
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