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Transcutaneous cervical vagus nerve stimulation reduces behavioral and physiological manifestations of withdrawal in patients with opioid use disorder: A double-blind, randomized, sham-controlled pilot study.
Gazi AH, Harrison AB, Lambert TP, Obideen M, Alavi P, Murrah N, Shallenberger L, Driggers EG, Ortega RA, Washington BP, Walton KM, Welsh JW, Vaccarino V, Shah AJ, Tang YL, Gupta R, Back SE, Inan OT, Bremner JD. Gazi AH, et al. Brain Stimul. 2022 Sep-Oct;15(5):1206-1214. doi: 10.1016/j.brs.2022.08.017. Epub 2022 Aug 27. Brain Stimul. 2022. PMID: 36041704 Free PMC article. Clinical Trial.
Transcutaneous Cervical Vagus Nerve Stimulation Modulates Prefrontal Cortex Activity During Opioid Withdrawal in Individuals With Opioid Use Disorder.
Rahman FN, Nawar A, Nye JA, Choi J, Lambert TP, Robinson M, Gazi AH, Abbaraju V, Tomic N, Harrison AB, Jaquemet N, Mermin-Bunnell K, Mesfin H, Gray TA, Welsh JW, Dunn KE, Bikson M, Vaccarino V, Shah AJ, Inan OT, Bremner JD. Rahman FN, et al. Neuromodulation. 2025 Jun 23:S1094-7159(25)00190-4. doi: 10.1016/j.neurom.2025.04.012. Online ahead of print. Neuromodulation. 2025. PMID: 40548916