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. 2022 Apr 15;23(1):315.
doi: 10.1186/s13063-022-06153-8.

Comparison of the open kinetic chain and closed kinetic chain strengthening exercises on pain perception and lower limb biomechanics of patients with mild knee osteoarthritis: a randomized controlled trial protocol

Wei Hui Ng  1   2 , Nazatul Izzati Jamaludin  1 , Farhah Nadhirah Aiman Sahabuddin  1 , Shaifuzain Ab Rahman  3 , Amran Ahmed Shokri  3 , Shazlin Shaharudin  4
Affiliations

Comparison of the open kinetic chain and closed kinetic chain strengthening exercises on pain perception and lower limb biomechanics of patients with mild knee osteoarthritis: a randomized controlled trial protocol

Wei Hui Ng et al. Trials. .

Abstract

Background: Clinical recommendations suggest exercises as the main treatment modality for patients with knee osteoarthritis (OA). This study aimed to compare the effects of two different exercise interventions, i.e., open kinetic chain (OKC) and closed kinetic chain (CKC) exercises, on the pain and lower limb biomechanics of patients with mild knee OA.

Method: A total of 66 individuals with painful early knee OA, aged 50 years and above, with body mass index (BMI) between 18.9kg/m2 and 29.9 kg/m2 in Kelantan, Malaysia, will be recruited in this study. Participants will be randomly allocated into three different groups, either the OKC, CKC, or control groups. All three groups will attend an individual session with a physiotherapist. The participants in the OKC and CKC groups will perform the exercises three times weekly for 8 weeks at their home. The control group will receive education about clinical manifestations, risk factors, diagnosis, treatment, and nursing care for knee via printed materials. The primary outcomes include self-reported pain scores (visual analog scale), disability scores (Western Ontario and McMaster Universities Arthritis Index), and quality of life scores (Osteoarthritis Knee and Hip Quality of Life). Secondary outcomes include lower limb biomechanics during gait and sit-to-stand as well as isokinetic knee strength. The outcomes will be measured before and after the intervention.

Discussion: The present study will compare the effects of two different home-based exercise intervention programs among patients with mild knee OA. The study findings will provide vital information that can be used to design an effective exercise program that aims at delaying the OA progression.

Trial registration: The protocol was registered on 22 December 2020 at ClinicalTrials.gov (registration number: NCT04678609 ).

Keywords: Home-based exercise program; Knee osteoarthritis; Physiotherapy.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Participant flow through the randomized controlled trial
Fig. 2
Fig. 2
The schedule of enrolment, interventions, and assessments
Fig. 3
Fig. 3
Open kinetic chain exercise program
Fig. 4
Fig. 4
Closed kinetic chain exercise program
See this image and copyright information in PMC

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