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Twice-A-Day CLOpidogrel vs Ticagrelor to Reduce Short-Term MACE after Primary PCI: The TADCLOT Trial.
Hakeem A, Shah JA, Kumar R, Ali A, Lakho AA, Zeeshan H, Uddin MI, Khan K, Solangi B, Kumar M, Kumar M, Awan R, Ishaq H, Farooq F, Haq EU, Hameed A, Lehri WA, Zada S, Ali A, Raza A, Masood S, Humza A, Karim M; TADCLOT investigators*. Hakeem A, et al. J Am Coll Cardiol. 2025 Aug 22:S0735-1097(25)07549-7. doi: 10.1016/j.jacc.2025.08.041. Online ahead of print. J Am Coll Cardiol. 2025. PMID: 40892606
Rationale and design of the TADCLOT trial: A double blind randomized controlled trial comparing twice a day clopidogrel vs ticagrelor in reducing major cardiac events in patients with acute STEMI undergoing primary percutaneous coronary intervention.
Hakeem A, Ali Shah J, Kumar R, Khan K, Zeeshan H, Lakho AA, Ali A, Uddin MI, Solangi B, Kumar M, Kumar M, Awan R, Dilawar F, Ishaq H, Farooq F, Ul Haq E, Hameed A, Lehri WA, Zada S, Raza A, Masood S, Humza A, Karim M. Hakeem A, et al. Am Heart J. 2025 Sep;287:141-150. doi: 10.1016/j.ahj.2025.03.021. Epub 2025 Apr 12. Am Heart J. 2025. PMID: 40228593