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Page 1
A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity.
Jacob F, Salinas RD, Zhang DY, Nguyen PTT, Schnoll JG, Wong SZH, Thokala R, Sheikh S, Saxena D, Prokop S, Liu DA, Qian X, Petrov D, Lucas T, Chen HI, Dorsey JF, Christian KM, Binder ZA, Nasrallah M, Brem S, O'Rourke DM, Ming GL, Song H. Jacob F, et al. Among authors: nguyen ptt. Cell. 2020 Jan 9;180(1):188-204.e22. doi: 10.1016/j.cell.2019.11.036. Epub 2019 Dec 26. Cell. 2020. PMID: 31883794 Free PMC article.
Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation.
Qian X, Su Y, Adam CD, Deutschmann AU, Pather SR, Goldberg EM, Su K, Li S, Lu L, Jacob F, Nguyen PTT, Huh S, Hoke A, Swinford-Jackson SE, Wen Z, Gu X, Pierce RC, Wu H, Briand LA, Chen HI, Wolf JA, Song H, Ming GL. Qian X, et al. Among authors: nguyen ptt. Cell Stem Cell. 2020 May 7;26(5):766-781.e9. doi: 10.1016/j.stem.2020.02.002. Epub 2020 Mar 5. Cell Stem Cell. 2020. PMID: 32142682 Free PMC article.
Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells.
Huang WK, Wong SZH, Pather SR, Nguyen PTT, Zhang F, Zhang DY, Zhang Z, Lu L, Fang W, Chen L, Fernandes A, Su Y, Song H, Ming GL. Huang WK, et al. Among authors: nguyen ptt. Cell Stem Cell. 2021 Sep 2;28(9):1657-1670.e10. doi: 10.1016/j.stem.2021.04.006. Epub 2021 May 6. Cell Stem Cell. 2021. PMID: 33961804 Free PMC article.
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis.
Izzo LT, Trefely S, Demetriadou C, Drummond JM, Mizukami T, Kuprasertkul N, Farria AT, Nguyen PTT, Murali N, Reich L, Kantner DS, Shaffer J, Affronti H, Carrer A, Andrews A, Capell BC, Snyder NW, Wellen KE. Izzo LT, et al. Among authors: nguyen ptt. Sci Adv. 2023 May 3;9(18):eadf0115. doi: 10.1126/sciadv.adf0115. Epub 2023 May 3. Sci Adv. 2023. PMID: 37134161 Free PMC article.
Bempedoic acid suppresses diet-induced hepatic steatosis independently of ATP-citrate lyase.
Liu JY, Kuna RS, Pinheiro LV, Nguyen PTT, Welles JE, Drummond JM, Murali N, Sharma PV, Supplee JG, Shiue M, Zhao S, Farria AT, Kumar A, Ruchhoeft ML, Demetriadou C, Kantner DS, Chatoff A, Megill E, Titchenell PM, Snyder NW, Metallo CM, Wellen KE. Liu JY, et al. Among authors: nguyen ptt. Cell Metab. 2025 Jan 7;37(1):239-254.e7. doi: 10.1016/j.cmet.2024.10.014. Epub 2024 Oct 28. Cell Metab. 2025. PMID: 39471816
Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis.
Nguyen PTT, Shiue M, Kuprasertkul N, Costa-Pinheiro P, Izzo LT, Pinheiro LV, Affronti HA, Gugiu G, Ghaisas S, Liu JY, Harris JC, Bradley CW, Seykora JT, Yang X, Kambayashi T, Mesaros C, Capell BC, Wellen KE. Nguyen PTT, et al. Cell Rep. 2025 Feb 25;44(2):115284. doi: 10.1016/j.celrep.2025.115284. Epub 2025 Feb 10. Cell Rep. 2025. PMID: 39932848 Free PMC article.
Novel approaches to clinical trial design in cancer neuroscience.
Jones G, Anderson JL, Nguyen PTT, Gleber-Netto FO, Hwang WL, Puduvalli VK, Monje M, Amit M. Jones G, et al. Among authors: nguyen ptt. Neuron. 2025 Sep 3;113(17):2791-2813. doi: 10.1016/j.neuron.2025.08.015. Neuron. 2025. PMID: 40907474 Review.
A nuclear branched-chain amino acid catabolism pathway controls histone propionylation in pancreatic cancer.
Demetriadou C, Noji M, Good AL, Mitchell-Velasquez E, Venkatesh S, Kantner DS, Pennise J, Costa-Pinheiro P, Pinheiro LV, Harada T, Nguyen PTT, Chatoff A, Megill E, Crispim CVDS, Marcinkiewicz MM, Meier JL, Arany Z, Asangani I, Furth EE, Stanger BZ, Snyder NW, Wellen KE. Demetriadou C, et al. Among authors: nguyen ptt. bioRxiv [Preprint]. 2025 Apr 26:2025.04.23.650241. doi: 10.1101/2025.04.23.650241. bioRxiv. 2025. PMID: 40568091 Free PMC article. Preprint.
69 results