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1954 5
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38 results

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Page 1
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.
Sheehan PW, Nadarajah CJ, Kanan MF, Patterson JN, Novotny B, Lawrence JH, King MW, Brase L, Inman CE, Yuede CM, Lee J, Patel TK, Harari O, Benitez BA, Davis AA, Musiek ES. Sheehan PW, et al. Among authors: novotny b. Neuron. 2023 Aug 2;111(15):2383-2398.e7. doi: 10.1016/j.neuron.2023.05.006. Epub 2023 Jun 13. Neuron. 2023. PMID: 37315555 Free PMC article.
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Gratuze M, Schlachetzki JCM, D'Oliveira Albanus R, Jain N, Novotny B, Brase L, Rodriguez L, Mansel C, Kipnis M, O'Brien S, Pasillas MP, Lee C, Manis M, Colonna M, Harari O, Glass CK, Ulrich JD, Holtzman DM. Gratuze M, et al. Among authors: novotny b. Neuron. 2023 Jan 18;111(2):202-219.e7. doi: 10.1016/j.neuron.2022.10.022. Epub 2022 Nov 10. Neuron. 2023. PMID: 36368315 Free PMC article.
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers.
Brase L, You SF, D'Oliveira Albanus R, Del-Aguila JL, Dai Y, Novotny BC, Soriano-Tarraga C, Dykstra T, Fernandez MV, Budde JP, Bergmann K, Morris JC, Bateman RJ, Perrin RJ, McDade E, Xiong C, Goate AM, Farlow M; Dominantly Inherited Alzheimer Network (DIAN); Sutherland GT, Kipnis J, Karch CM, Benitez BA, Harari O. Brase L, et al. Among authors: novotny bc. Nat Commun. 2023 Apr 21;14(1):2314. doi: 10.1038/s41467-023-37437-5. Nat Commun. 2023. PMID: 37085492 Free PMC article.
Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease.
Eteleeb AM, Novotny BC, Tarraga CS, Sohn C, Dhungel E, Brase L, Nallapu A, Buss J, Farias F, Bergmann K, Bradley J, Norton J, Gentsch J, Wang F, Davis AA, Morris JC, Karch CM, Perrin RJ, Benitez BA, Harari O. Eteleeb AM, et al. Among authors: novotny bc. PLoS Biol. 2024 Apr 30;22(4):e3002607. doi: 10.1371/journal.pbio.3002607. eCollection 2024 Apr. PLoS Biol. 2024. PMID: 38687811 Free PMC article.
Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease.
Sung YJ, Yang C, Norton J, Johnson M, Fagan A, Bateman RJ, Perrin RJ, Morris JC, Farlow MR, Chhatwal JP, Schofield PR, Chui H, Wang F, Novotny B, Eteleeb A, Karch C, Schindler SE, Rhinn H, Johnson ECB, Oh HS, Rutledge JE, Dammer EB, Seyfried NT, Wyss-Coray T, Harari O, Cruchaga C. Sung YJ, et al. Among authors: novotny b. Sci Transl Med. 2023 Jul 5;15(703):eabq5923. doi: 10.1126/scitranslmed.abq5923. Epub 2023 Jul 5. Sci Transl Med. 2023. PMID: 37406134 Free PMC article.
Systematic analysis of cellular cross-talk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer's disease.
D'Oliveira Albanus R, Finan GM, Brase L, Sweeney N, Kim TY, Chen S, Ryoo Y, Park J, Guo Q, Iyer AK, Acquarone M, You SF, Novotny BC, Mace EM, Ribeiro Pereira PM, Morris JC, Holtzman DM, McDade E, Farlow M, Chhatwal JP, Benitez BA, Piccio L, Perrin RJ, Sutherland GT, Ma Q, Karch CM, Kim DY, Tanzi RE, Fu H, Harari O, Kim TW. D'Oliveira Albanus R, et al. Among authors: novotny bc. Sci Transl Med. 2025 Jul 30;17(809):eadx0027. doi: 10.1126/scitranslmed.adx0027. Epub 2025 Jul 30. Sci Transl Med. 2025. PMID: 40737431
Generating dermatopathology reports from gigapixel whole slide images with HistoGPT.
Tran M, Schmidle P, Guo RR, Wagner SJ, Koch V, Lupperger V, Novotny B, Murphree DH, Hardway HD, D'Amato M, Lefkes J, Geijs DJ, Feuchtinger A, Böhner A, Kaczmarczyk R, Biedermann T, Amir AL, Mooyaart AL, Ciompi F, Litjens G, Wang C, Comfere NI, Eyerich K, Braun SA, Marr C, Peng T. Tran M, et al. Among authors: novotny b. Nat Commun. 2025 May 27;16(1):4886. doi: 10.1038/s41467-025-60014-x. Nat Commun. 2025. PMID: 40419470 Free PMC article.
38 results