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Page 1
Supersulphides provide airway protection in viral and chronic lung diseases.
Matsunaga T, Sano H, Takita K, Morita M, Yamanaka S, Ichikawa T, Numakura T, Ida T, Jung M, Ogata S, Yoon S, Fujino N, Kyogoku Y, Sasaki Y, Koarai A, Tamada T, Toyama A, Nakabayashi T, Kageyama L, Kyuwa S, Inaba K, Watanabe S, Nagy P, Sawa T, Oshiumi H, Ichinose M, Yamada M, Sugiura H, Wei FY, Motohashi H, Akaike T. Matsunaga T, et al. Among authors: numakura t. Nat Commun. 2023 Jul 25;14(1):4476. doi: 10.1038/s41467-023-40182-4. Nat Commun. 2023. PMID: 37491435 Free PMC article.
Supersulfide controls intestinal inflammation by suppressing CD4+ T cell proliferation.
Tayama S, Kitamura Y, Hiraide K, Suzuki H, Li J, Yang Z, Mitsuwaka R, Kawajiri A, Sato K, Gao F, Nakai T, Okuyama Y, Numakura T, Yamada M, Ida T, Morita M, Kawabe T, Akaike T, Ishii N. Tayama S, et al. Among authors: numakura t. Front Immunol. 2025 Apr 15;16:1506580. doi: 10.3389/fimmu.2025.1506580. eCollection 2025. Front Immunol. 2025. PMID: 40303402 Free PMC article.
Phase 3 Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis.
Trapnell BC, Inoue Y, Bonella F, Wang T, McCarthy C, Arai T, Akasaka K, Mariani F, Mogulkoc N, Song JW, Baba T, Jouneau S, Numakura T, Öcal N, Mihaltan F, Ataya A, Bendstrup E, Campo I, Carey B, Arena R, Robinson B, Fleming R, Wasfi Y, Pratt R; IMPALA-2 Trial Investigators. Trapnell BC, et al. Among authors: numakura t. N Engl J Med. 2025 Aug 21;393(8):764-773. doi: 10.1056/NEJMoa2410542. N Engl J Med. 2025. PMID: 40834301 Clinical Trial.
Identification of Siglec-1-negative alveolar macrophages with proinflammatory phenotypes in chronic obstructive pulmonary disease.
Saito T, Fujino N, Kyogoku Y, Yamada M, Okutomo K, Ono Y, Konno S, Endo T, Itakura K, Matsumoto S, Sano H, Aizawa H, Numakura T, Onodera K, Okada Y, Hussell T, Ichinose M, Sugiura H. Saito T, et al. Among authors: numakura t. Am J Physiol Lung Cell Mol Physiol. 2024 Jun 1;326(6):L672-L686. doi: 10.1152/ajplung.00303.2023. Epub 2024 Mar 26. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 38530936 Free article.
Metabolic and Epigenetic Regulation of SMAD7 by STC1 Ameliorates Lung Fibrosis.
Ohkouchi S, Kanehira M, Saigusa D, Ono M, Tazawa R, Terunuma H, Hirano T, Numakura T, Notsuda H, Inoue C, Saito-Koyama R, Tabata M, Irokawa T, Ogawa H, Kurosawa H, Okada Y. Ohkouchi S, et al. Among authors: numakura t. Am J Respir Cell Mol Biol. 2022 Sep;67(3):320-333. doi: 10.1165/rcmb.2021-0445OC. Am J Respir Cell Mol Biol. 2022. PMID: 35696344
Nitrosative stress in patients with asthma-chronic obstructive pulmonary disease overlap.
Kyogoku Y, Sugiura H, Ichikawa T, Numakura T, Koarai A, Yamada M, Fujino N, Tojo Y, Onodera K, Tanaka R, Sato K, Sano H, Yamanaka S, Itakura K, Mitsune A, Tamada T, Akaike T, Ichinose M. Kyogoku Y, et al. Among authors: numakura t. J Allergy Clin Immunol. 2019 Oct;144(4):972-983.e14. doi: 10.1016/j.jaci.2019.04.023. Epub 2019 May 9. J Allergy Clin Immunol. 2019. PMID: 31077687
Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma.
Itakura K, Fujino N, Kamide Y, Saito I, Yamada M, Okutomo K, Tsukita Y, Saito T, Ichikawa T, Numakura T, Kyogoku Y, Aizawa H, Ono Y, Matsumoto S, Hussell T, Taniguchi M, Ichinose M, Sugiura H. Itakura K, et al. Among authors: numakura t. Allergol Int. 2022 Jul;71(3):383-394. doi: 10.1016/j.alit.2022.02.010. Epub 2022 Apr 20. Allergol Int. 2022. PMID: 35459569 Free article.
44 results