Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1976 1
1977 2
1978 3
1979 1
1980 1
1985 1
1986 2
1988 1
1993 1
1994 1
1996 5
1997 17
1998 19
1999 18
2000 24
2001 27
2002 29
2003 27
2004 34
2005 26
2006 33
2007 30
2008 20
2009 26
2010 31
2011 29
2012 20
2013 35
2014 20
2015 22
2016 18
2017 26
2018 14
2019 28
2020 27
2021 22
2022 27
2023 17
2024 22
2025 16

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

660 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for ob rb
Search for Obe RB instead (2 results)
A role for dietary fat in leptin receptor, OB-Rb, function.
Heshka JT, Jones PJ. Heshka JT, et al. Life Sci. 2001 Jul 20;69(9):987-1003. doi: 10.1016/s0024-3205(01)01201-2. Life Sci. 2001. PMID: 11508653 Review.
Both the type and amount of dietary fat have been shown to affect factors involved in OB-Rb binding and signaling, as well as the morphology of hypothalamic cell membranes. ...Dietary fat also interferes in biochemical pathways involving leptin, OB-Rb, …
Both the type and amount of dietary fat have been shown to affect factors involved in OB-Rb binding and signaling, as well as …
Leptin receptors.
Gorska E, Popko K, Stelmaszczyk-Emmel A, Ciepiela O, Kucharska A, Wasik M. Gorska E, et al. Eur J Med Res. 2010 Nov 4;15 Suppl 2(Suppl 2):50-4. doi: 10.1186/2047-783x-15-s2-50. Eur J Med Res. 2010. PMID: 21147620 Free PMC article. Review.
Ob-Rb is also present on all types of immune cells, involved in innate and adaptive immunity. ...JAK/STAT pathway plays the major role in leptin signal transduction through membrane receptors. Among all Ob-R isoforms, only full-length isoform (Ob-Rb …
Ob-Rb is also present on all types of immune cells, involved in innate and adaptive immunity. ...JAK/STAT pathway plays the ma …
Diet-Induced Obesity and the Mechanism of Leptin Resistance.
Engin A. Engin A. Adv Exp Med Biol. 2017;960:381-397. doi: 10.1007/978-3-319-48382-5_16. Adv Exp Med Biol. 2017. PMID: 28585208 Review.
Leptin signaling blockade by chronic overstimulation of the leptin receptor or hypothalamic pro-inflammatory responses due to elevated levels of saturated fatty acid can induce leptin resistance by activating negative feedback pathways. Although, long form leptin receptor (Ob …
Leptin signaling blockade by chronic overstimulation of the leptin receptor or hypothalamic pro-inflammatory responses due to elevated level …
Leptin induces IL-6 and IL-8 expression through leptin receptor Ob-Rb in human dental pulp fibroblasts.
Wei L, Chen Y, Zhang C, Liu M, Xiong H. Wei L, et al. Acta Odontol Scand. 2019 Apr;77(3):205-212. doi: 10.1080/00016357.2018.1536280. Epub 2019 Jan 2. Acta Odontol Scand. 2019. PMID: 30600742
OBJECTIVE: Leptin, through binding to its special receptor (Ob-Rb), has potent effects on immunity and inflammation. This study aimed to investigate the expression of leptin receptor Ob-Rb in human dental pulp fibroblasts (HDPFs) and the effects of lep …
OBJECTIVE: Leptin, through binding to its special receptor (Ob-Rb), has potent effects on immunity and inflammation. This stud …
Activation of the leptin pathway by high expression of the long form of the leptin receptor (Ob-Rb) accelerates chondrocyte senescence in osteoarthritis.
Zhao X, Huang P, Li G, Lv Z, Hu G, Xu Q. Zhao X, et al. Bone Joint Res. 2019 Oct 3;8(9):425-436. doi: 10.1302/2046-3758.89.BJR-2018-0325.R2. eCollection 2019 Sep. Bone Joint Res. 2019. PMID: 31588359 Free PMC article.
However, the role of the long form of the leptin receptor (Ob-Rb) in cartilage degeneration needs further study. The aim of this study was to determine the effect of increasing the expression of Ob-Rb on chondrocytes using a lentiviral vector containin …
However, the role of the long form of the leptin receptor (Ob-Rb) in cartilage degeneration needs further study. The aim of th …
Drug targeting of leptin resistance.
Santoro A, Mattace Raso G, Meli R. Santoro A, et al. Life Sci. 2015 Nov 1;140:64-74. doi: 10.1016/j.lfs.2015.05.012. Epub 2015 Jun 9. Life Sci. 2015. PMID: 26071010 Review.
Indeed, this adipocyte-derived hormone, whose circulating levels mirror fat mass, not only exerts its anti-obesity effects mainly modulating the activity of specific hypothalamic neurons expressing the long form of the leptin receptor (Ob-Rb), but it also shows plei …
Indeed, this adipocyte-derived hormone, whose circulating levels mirror fat mass, not only exerts its anti-obesity effects mainly modulating …
Circadian rhythm in hypothalamic leptin receptor (Ob-Rb) mRNA expressions and cerebrospinal fluid and circulating glucose and leptin levels in lactating rats.
Suzuki Y, Takagishi K, Kurose Y. Suzuki Y, et al. Biochem Biophys Rep. 2021 Sep 8;28:101129. doi: 10.1016/j.bbrep.2021.101129. eCollection 2021 Dec. Biochem Biophys Rep. 2021. PMID: 34541341 Free PMC article.
However, the expression of the hypothalamic Ob-Rb mRNA showed similar circadian rhythms in both the non-lactation and lactation, with only slight differences between the two groups. ...In conclusion, the present study provides evidence that Ob-Rb mRNA …
However, the expression of the hypothalamic Ob-Rb mRNA showed similar circadian rhythms in both the non-lactation and lactatio …
Leptin and Ob-Rb receptor isoform in the human digestive tract during fetal development.
Aparicio T, Kermorgant S, Darmoul D, Guilmeau S, Hormi K, Mahieu-Caputo D, Lehy T. Aparicio T, et al. J Clin Endocrinol Metab. 2005 Nov;90(11):6177-84. doi: 10.1210/jc.2005-1498. Epub 2005 Sep 6. J Clin Endocrinol Metab. 2005. PMID: 16144948
It also regulates some digestive functions through its functional receptor Ob-Rb expressed by gastrointestinal epithelial cells. OBJECTIVE: The objective of the study was to investigate the temporal and spatial appearance of Ob-Rb in the human digestiv …
It also regulates some digestive functions through its functional receptor Ob-Rb expressed by gastrointestinal epithelial cell …
Aging entails distinct requirements for Rb at maintaining adult neurogenesis.
Omais S, Hilal RN, Halaby NN, Jaafar C, Ghanem N. Omais S, et al. Aging Brain. 2022 May 11;2:100041. doi: 10.1016/j.nbas.2022.100041. eCollection 2022. Aging Brain. 2022. PMID: 36908894 Free PMC article.
In this study, we find no evidence of irregular proliferation or early commitment defects in the mid-aged (12-month-old) and old-aged (20-month-old) SVZ following tamoxifen-inducible Rb knockout (Rb iKO) in mice. However, we highlight a striking defect in early matu …
In this study, we find no evidence of irregular proliferation or early commitment defects in the mid-aged (12-month-old) and old-aged (20-mo …
Leptin receptor expression in the rat placenta: changes in ob-ra, ob-rb, and ob-re with gestational age and suppression by glucocorticoids.
Smith JT, Waddell BJ. Smith JT, et al. Biol Reprod. 2002 Oct;67(4):1204-10. doi: 10.1095/biolreprod67.4.1204. Biol Reprod. 2002. PMID: 12297537
Ob-Ra and Ob-Re mRNA expression increased markedly (P < 0.01) from Day 16 to Day 22 in the labyrinth but not in the basal zone, whereas Ob-Rb mRNA and protein remained relatively stable. ...In conclusion, our data indicate that placental expression …
Ob-Ra and Ob-Re mRNA expression increased markedly (P < 0.01) from Day 16 to Day 22 in the labyrinth but not in the basal z …
660 results