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2,309 results

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Page 1
Showing results for offer ka
Search for Offei KA instead (1 results)
The Kainic Acid Models of Temporal Lobe Epilepsy.
Rusina E, Bernard C, Williamson A. Rusina E, et al. eNeuro. 2021 Apr 9;8(2):ENEURO.0337-20.2021. doi: 10.1523/ENEURO.0337-20.2021. Print 2021 Mar-Apr. eNeuro. 2021. PMID: 33658312 Free PMC article. Review.
Experimental models of epilepsy are useful to identify potential mechanisms of epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA) model is one of the most commonly used. Several modes of administration of KA exist, each pro …
Experimental models of epilepsy are useful to identify potential mechanisms of epileptogenesis, seizure genesis, comorbidities, and treatmen …
Role of oxeiptosis in disease mechanisms and therapeutic opportunities.
Bhuvaneshwari K, Harithpriya K, Ganesan K, Xu B, Ramkumar KM. Bhuvaneshwari K, et al. Apoptosis. 2025 Jun;30(5-6):1182-1201. doi: 10.1007/s10495-025-02087-z. Epub 2025 Mar 10. Apoptosis. 2025. PMID: 40064755 Review.
Modulating oxeiptosis presents significant clinical implications by offering novel therapeutic strategies to mitigate oxidative stress, restore cellular homeostasis, and prevent inflammation-driven diseases. This review emphasizes potential therapeutic advances for conditi …
Modulating oxeiptosis presents significant clinical implications by offering novel therapeutic strategies to mitigate oxidative stres …
Mapping the pancancer metastasis tumor microbiome.
Wong CC, Yu J. Wong CC, et al. Cell. 2024 Apr 25;187(9):2126-2128. doi: 10.1016/j.cell.2024.03.040. Cell. 2024. PMID: 38670070 Free article.
In this issue of Cell, Voest et al. profiled the tumor metastasis-associated microbiome in a pancancer cohort of 4,160 biopsies from 26 cancer types. This dataset offers a useful resource for understanding the role of the microbiome in metastatic cancers....
In this issue of Cell, Voest et al. profiled the tumor metastasis-associated microbiome in a pancancer cohort of 4,160 biopsies from 26 canc …
What is Interpretability?
Erasmus A, Brunet TDP, Fisher E. Erasmus A, et al. Philos Technol. 2021;34(4):833-862. doi: 10.1007/s13347-020-00435-2. Epub 2020 Nov 12. Philos Technol. 2021. PMID: 34966640 Free PMC article.
We argue that artificial networks are explainable and offer a novel theory of interpretability. Two sets of conceptual questions are prominent in theoretical engagements with artificial neural networks, especially in the context of medical artificial intelligence: (1) Are …
We argue that artificial networks are explainable and offer a novel theory of interpretability. Two sets of conceptual questions are …
Intranasal influenza virus-vectored vaccine offers protection against clade 2.3.4.4b H5N1 infection in small animal models.
Liu Y, Deng S, Ren S, Tam RC, Liu S, Zhang AJ, To KK, Yuen KY, Chen H, Wang P. Liu Y, et al. Nat Commun. 2025 Apr 1;16(1):3133. doi: 10.1038/s41467-025-58504-z. Nat Commun. 2025. PMID: 40169649 Free PMC article.
Our research demonstrates that a single intranasal immunization can provide effective protection against lethal challenges from HPAI cattle or mink H5N1 variants, offering strong, sustained immunity after two months in female mouse and male hamster models. ...
Our research demonstrates that a single intranasal immunization can provide effective protection against lethal challenges from HPAI cattle …
Advances in molecular glues: exploring chemical space and design principles for targeted protein degradation.
Hemant Kumar S, Venkatachalapathy M, Sistla R, Poongavanam V. Hemant Kumar S, et al. Drug Discov Today. 2024 Nov;29(11):104205. doi: 10.1016/j.drudis.2024.104205. Epub 2024 Oct 10. Drug Discov Today. 2024. PMID: 39393773 Free article. Review.
Recently, the emergence of low-molecular-weight molecular glue degraders (MGDs) has expanded the TPD landscape, because MGDs operate via the same mechanism while offering attractive physicochemical properties that are consistent with small-molecule therapeutics. ...
Recently, the emergence of low-molecular-weight molecular glue degraders (MGDs) has expanded the TPD landscape, because MGDs operate via the …
[Methods for fertility preservation].
Rodriguez-Wallberg K. Rodriguez-Wallberg K. Lakartidningen. 2023 Jan 4;120:22071. Lakartidningen. 2023. PMID: 36598163 Free article. Swedish.
In Sweden, such programs are established at university hospitals and fertility preservation is offered within the publicly financed healthcare to patients when medically indicated. The largest patient groups undergoing procedures for fertility preservation include those wi …
In Sweden, such programs are established at university hospitals and fertility preservation is offered within the publicly financed h …
Memory-Replay Knowledge Distillation.
Wang J, Zhang P, Li Y. Wang J, et al. Sensors (Basel). 2021 Apr 15;21(8):2792. doi: 10.3390/s21082792. Sensors (Basel). 2021. PMID: 33921068 Free PMC article.
Secondly, a simple Fully Connected Network (FCN) is applied to ensemble the historical teacher's output for a better guidance. Finally, to ensure the teacher outputs offer the right class as ground truth, we correct the teacher logit output by the Knowledge Adjustment ( …
Secondly, a simple Fully Connected Network (FCN) is applied to ensemble the historical teacher's output for a better guidance. Finally, to e …
[Dementia in Down syndrome].
Granholm AC, Larsson L, Öhman F, Zetterberg H, Hansson O, Eriksdotter M, Kern S, Nordberg A. Granholm AC, et al. Lakartidningen. 2024 Sep 30;121:23083. Lakartidningen. 2024. PMID: 39354735 Free article. Swedish.
Adults with DS should be included in memory clinic assessments and offered appropriate medications available to the general population with dementia. The Swedish dementia registry, SveDem, has added the diagnosis AD due to the genetic overload in DS, providing a national d …
Adults with DS should be included in memory clinic assessments and offered appropriate medications available to the general populatio …
2,309 results