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Year Number of Results
2009 1
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2025 7

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38 results

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Page 1
High-resolution functional mapping of RAD51C by saturation genome editing.
Olvera-León R, Zhang F, Offord V, Zhao Y, Tan HK, Gupta P, Pal T, Robles-Espinoza CD, Arriaga-González FG, Matsuyama LSAS, Delage E, Dicks E, Ezquina S, Rowlands CF, Turnbull C, Pharoah P, Perry JRB, Jasin M, Waters AJ, Adams DJ. Olvera-León R, et al. Among authors: offord v. Cell. 2024 Oct 3;187(20):5719-5734.e19. doi: 10.1016/j.cell.2024.08.039. Epub 2024 Sep 18. Cell. 2024. PMID: 39299233 Free PMC article.
Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants.
Perkin MR, Logan K, Tseng A, Raji B, Ayis S, Peacock J, Brough H, Marrs T, Radulovic S, Craven J, Flohr C, Lack G; EAT Study Team. Perkin MR, et al. N Engl J Med. 2016 May 5;374(18):1733-43. doi: 10.1056/NEJMoa1514210. Epub 2016 Mar 4. N Engl J Med. 2016. PMID: 26943128 Free article. Clinical Trial.
Saturation genome editing of BAP1 functionally classifies somatic and germline variants.
Waters AJ, Brendler-Spaeth T, Smith D, Offord V, Tan HK, Zhao Y, Obolenski S, Nielsen M, van Doorn R, Murphy JE, Gupta P, Rowlands CF, Hanson H, Delage E, Thomas M, Radford EJ, Gerety SS, Turnbull C, Perry JRB, Hurles ME, Adams DJ. Waters AJ, et al. Among authors: offord v. Nat Genet. 2024 Jul;56(7):1434-1445. doi: 10.1038/s41588-024-01799-3. Epub 2024 Jul 5. Nat Genet. 2024. PMID: 38969833 Free PMC article.
Wnt/β-catenin activation by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary basal cell adenoma.
Wong K, Bishop JA, Weinreb I, Motta M, Del Castillo Velasco-Herrera M, Bellacchio E, Ferreira I, van der Weyden L, Boccacino JM, Lauri A, Rotundo G, Ciolfi A, Cheema S, Olvera-León R, Offord V, Droop A, Vermes I, Allgäuer M, Hyrcza M, Anderson E, Smith K, de Saint Aubain N, Mogler C, Stenzinger A, Arends MJ, Brenn T, Tartaglia M, Adams DJ. Wong K, et al. Among authors: offord v. Nat Commun. 2025 May 19;16(1):4657. doi: 10.1038/s41467-025-59871-3. Nat Commun. 2025. PMID: 40389436 Free PMC article.
HIRA loss transforms FH-deficient cells.
Valcarcel-Jimenez L, Rogerson C, Yong C, Schmidt C, Yang M, Cremades-Rodelgo M, Harle V, Offord V, Wong K, Mora A, Speed A, Caraffini V, Tran MGB, Maher ER, Stewart GD, Vanharanta S, Adams DJ, Frezza C. Valcarcel-Jimenez L, et al. Among authors: offord v. Sci Adv. 2022 Oct 21;8(42):eabq8297. doi: 10.1126/sciadv.abq8297. Epub 2022 Oct 21. Sci Adv. 2022. PMID: 36269833 Free PMC article.
The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types.
Chan PY, Alexander D, Mehta I, Matsuyama LSAS, Harle V, Olvera-León R, Park JS, Arriaga-González FG, van der Weyden L, Cheema S, Iyer V, Offord V, Barneda D, Hawkins PT, Stephens L, Kozik Z, Woods M, Wong K, Balmus G, Vinceti A, Thompson NA, Del Castillo Velasco-Herrera M, Wessels L, van de Haar J, Gonçalves E, Sinha S, Vázquez-Cruz ME, Bisceglia L, Raimondi F, Choudhary J, Patiyal S, Venkatesh A, Iorio F, Ryan CJ, Adams DJ. Chan PY, et al. Among authors: offord v. Nat Genet. 2025 Jul;57(7):1672-1683. doi: 10.1038/s41588-025-02222-1. Epub 2025 Jul 4. Nat Genet. 2025. PMID: 40615675 Free PMC article.
Knockout of SIN3B modulates transcriptional programs and cell survival in cutaneous melanoma.
Alcantara Sekimoto Matsuyama LS, Harle V, Offord V, Droop A, Rabbie R, Garg M, Vázquez-Cruz ME, Robles-Espinoza CD, Turner G, Fraser D, de Oliveira ÉA, Gonçalves de Carvalho D, Nogueira Jorge NA, Boroni M, A Possik P, Adams DJ, Maria-Engler SS. Alcantara Sekimoto Matsuyama LS, et al. Among authors: offord v. Pharmacol Res. 2025 Jul;217:107785. doi: 10.1016/j.phrs.2025.107785. Epub 2025 May 18. Pharmacol Res. 2025. PMID: 40393534 Free article.
Comprehensive mutational profiling identifies new driver events in cutaneous leiomyosarcoma.
van der Weyden L, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino JM, Offord V, Droop A, Jones DRA, Vermes I, Anderson E, Hardy C, de Saint Aubain N, Ferguson PM, Clarke EL, Merchant W, Mogler C, Frew D, Harms PW, Monteagudo C, Billings SD, Arends MJ, Ferreira I, Brenn T, Adams DJ. van der Weyden L, et al. Among authors: offord v. Br J Dermatol. 2025 Jan 24;192(2):335-343. doi: 10.1093/bjd/ljae386. Br J Dermatol. 2025. PMID: 39392932 Free PMC article.
A compendium of synthetic lethal gene pairs defined by extensive combinatorial pan-cancer CRISPR screening.
Harle V, Offord V, Gökbağ B, Fotopoulos L, Williams T, Alexander D, Mehta I, Thompson NA, Olvera-León R, Peidli S, Iyer V, Gonçalves E, Kebabci N, De Kegel B, van de Haar J, Li L, Ryan CJ, Adams DJ. Harle V, et al. Among authors: offord v. Genome Biol. 2025 Sep 18;26(1):284. doi: 10.1186/s13059-025-03737-w. Genome Biol. 2025. PMID: 40968372 Free PMC article.
Exploration of the mutational landscape of cutaneous leiomyoma confirms FH as a driver gene and identifies targeting purine metabolism as a potential therapeutic strategy.
van der Weyden L, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino JM, Vermes I, Offord V, Droop A, Jones DRA, Anderson E, Hardy C, de Saint Aubain N, Ferguson PM, Mogler C, Rajan N, Frew D, Harms PW, Billings SD, Schatton D, Segarra-Mondejar M, Arends MJ, Ferreira I, Brenn T, Frezza C, Adams DJ. van der Weyden L, et al. Among authors: offord v. Br J Dermatol. 2025 Feb 18;192(3):551-553. doi: 10.1093/bjd/ljae432. Br J Dermatol. 2025. PMID: 39506538 Free PMC article.
38 results