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BREATHER Plus clinical trial design: A randomised non-inferiority trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily ART in virologically suppressed adolescents living with HIV aged 12 to <20 years in sub-Saharan Africa.
Katongole F, Arumugam T, Jennings A, Mutata C, Ssebunya P, Wamboi C, Green A, Bwakura-Dangarembizi M, Kityo C, Siika A, Archary M, Jafta L, Namukwaya S, Seeley J, Mugerwa H, Walker S, Apoto N, Thomason MJ, Ford D, Pett SL, Kekitiinwa AR; BREATHER Plus trial team. Katongole F, et al. Contemp Clin Trials. 2025 Aug;155:107963. doi: 10.1016/j.cct.2025.107963. Epub 2025 May 29. Contemp Clin Trials. 2025. PMID: 40449658 Free PMC article.
Added Value of Next Generation over Sanger Sequencing in Kenyan Youth with Extensive HIV-1 Drug Resistance.
Novitsky V, Nyandiko W, Vreeman R, DeLong AK, Manne A, Scanlon M, Ngeresa A, Aluoch J, Sang F, Ashimosi C, Jepkemboi E, Orido M, Hogan JW, Kantor R; RESistance in a PEdiatric CohorT (RESPECT) Study. Novitsky V, et al. Among authors: orido m. Microbiol Spectr. 2022 Dec 21;10(6):e0345422. doi: 10.1128/spectrum.03454-22. Epub 2022 Nov 29. Microbiol Spectr. 2022. PMID: 36445146 Free PMC article.
HemaSpot, a Novel Blood Storage Device for HIV-1 Drug Resistance Testing.
Brooks K, DeLong A, Balamane M, Schreier L, Orido M, Chepkenja M, Kemboi E, D'Antuono M, Chan PA, Emonyi W, Diero L, Coetzer M, Kantor R. Brooks K, et al. Among authors: orido m. J Clin Microbiol. 2016 Jan;54(1):223-5. doi: 10.1128/JCM.02853-15. Epub 2015 Nov 11. J Clin Microbiol. 2016. PMID: 26560534 Free PMC article.
Real-Life Feasibility of HIV Drug Resistance Testing Using Dried Filter Analytes in Kenyan Children and Adolescents Living with HIV.
Manne A, DeLong A, Nyandiko W, DeLong AK, Vreeman R, Novitsky V, Ngeresa A, Sang E, Chory A, Aluoch J, Jepkemboi E, Orido M, Ashimosi C, Sang F, Hogan JW, Kantor R; RESPECT (Resistance in a Pediatric Cohort) Study. Manne A, et al. Among authors: orido m. Microbiol Spectr. 2022 Apr 27;10(2):e0267521. doi: 10.1128/spectrum.02675-21. Epub 2022 Apr 7. Microbiol Spectr. 2022. PMID: 35389242 Free PMC article.
HIV-1 Treatment Failure, Drug Resistance, and Clinical Outcomes in Perinatally Infected Children and Adolescents Failing First-Line Antiretroviral Therapy in Western Kenya.
Nyandiko W, Holland S, Vreeman R, DeLong AK, Manne A, Novitsky V, Sang F, Ashimosi C, Ngeresa A, Chory A, Aluoch J, Orido M, Jepkemboi E, Sam SS, Caliendo AM, Ayaya S, Hogan JW, Kantor R; Resistance in a Pediatric Cohort (RESPECT) Study. Nyandiko W, et al. Among authors: orido m. J Acquir Immune Defic Syndr. 2022 Feb 1;89(2):231-239. doi: 10.1097/QAI.0000000000002850. J Acquir Immune Defic Syndr. 2022. PMID: 34723922 Free PMC article.
A Challenging Knowledge Gap: Estimating Modes of HIV Acquisition Among Adolescents Entering HIV Care During Adolescence.
Humphrey J, Triedman M, Nyandiko W, Sang E, Kemboi E, Alera M, Novitsky V, Manne A, Jepkemboi E, Orido M, Apondi E, Vreeman R, Wools-Kaloustian K, Kantor R. Humphrey J, et al. Among authors: orido m. Glob Pediatr Health. 2022 May 31;9:2333794X221101768. doi: 10.1177/2333794X221101768. eCollection 2022. Glob Pediatr Health. 2022. PMID: 35664047 Free PMC article.
15 results