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Page 1
Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis.
Meier S, Willemse EAJ, Schaedelin S, Oechtering J, Lorscheider J, Melie-Garcia L, Cagol A, Barakovic M, Galbusera R, Subramaniam S, Barro C, Abdelhak A, Thebault S, Achtnichts L, Lalive P, Müller S, Pot C, Salmen A, Disanto G, Zecca C, D'Souza M, Orleth A, Khalil M, Buchmann A, Du Pasquier R, Yaldizli Ö, Derfuss T, Berger K, Hermesdorf M, Wiendl H, Piehl F, Battaglini M, Fischer U, Kappos L, Gobbi C, Granziera C, Bridel C, Leppert D, Maleska Maceski A, Benkert P, Kuhle J. Meier S, et al. Among authors: orleth a. JAMA Neurol. 2023 Mar 1;80(3):287-297. doi: 10.1001/jamaneurol.2022.5250. JAMA Neurol. 2023. PMID: 36745446 Free PMC article.
Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study.
Benkert P, Meier S, Schaedelin S, Manouchehrinia A, Yaldizli Ö, Maceski A, Oechtering J, Achtnichts L, Conen D, Derfuss T, Lalive PH, Mueller C, Müller S, Naegelin Y, Oksenberg JR, Pot C, Salmen A, Willemse E, Kockum I, Blennow K, Zetterberg H, Gobbi C, Kappos L, Wiendl H, Berger K, Sormani MP, Granziera C, Piehl F, Leppert D, Kuhle J; NfL Reference Database in the Swiss Multiple Sclerosis Cohort Study Group. Benkert P, et al. Lancet Neurol. 2022 Mar;21(3):246-257. doi: 10.1016/S1474-4422(22)00009-6. Lancet Neurol. 2022. PMID: 35182510
MultiSCRIPT-Cycle 1-a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial.
Janiaud P, Zecca C, Salmen A, Benkert P, Schädelin S, Orleth A, Demuth L, Maceski AM, Granziera C, Oechtering J, Leppert D, Derfuss T, Achtnichts L, Findling O, Roth P, Lalive P, Uginet M, Müller S, Pot C, Hoepner R, Disanto G, Gobbi C, Rooshenas L, Schwenkglenks M, Lambiris MJ, Kappos L, Kuhle J, Yaldizli Ö, Hemkens LG. Janiaud P, et al. Among authors: orleth a. Trials. 2024 Sep 11;25(1):607. doi: 10.1186/s13063-024-08454-6. Trials. 2024. PMID: 39261900 Free PMC article.
Granulocyte activation markers in cerebrospinal fluid differentiate acute neuromyelitis spectrum disorder from multiple sclerosis.
Leppert D, Watanabe M, Schaedelin S, Piehl F, Furlan R, Gastaldi M, Lambert J, Evertsson B, Fink K, Matsushita T, Masaki K, Isobe N, Kira JI, Benkert P, Maceski A, Willemse E, Oechtering J, Orleth A, Meier S, Kuhle J. Leppert D, et al. Among authors: orleth a. J Neurol Neurosurg Psychiatry. 2023 Sep;94(9):726-737. doi: 10.1136/jnnp-2022-330796. Epub 2023 Apr 19. J Neurol Neurosurg Psychiatry. 2023. PMID: 37076291 Free PMC article.
Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis.
Abdelhak A, Benkert P, Schaedelin S, Boscardin WJ, Cordano C, Oechtering J, Ananth K, Granziera C, Melie-Garcia L, Montes SC, Beaudry-Richard A, Achtnichts L, Oertel FC, Lalive PH, Leppert D, Müller S, Henry RG, Pot C, Matthias A, Salmen A, Oksenberg JR, Disanto G, Zecca C, D'Souza M, Du Pasquier R, Bridel C, Gobbi C, Kappos L, Hauser SL, Cree BAC, Kuhle J, Green AJ; UCSF, MS EPIC, and the SMSC Study Teams. Abdelhak A, et al. JAMA Neurol. 2023 Dec 1;80(12):1317-1325. doi: 10.1001/jamaneurol.2023.3997. JAMA Neurol. 2023. PMID: 37930670 Free PMC article.
Aberrant Complement Activation Is Associated With Structural Brain Damage in Multiple Sclerosis.
Oechtering J, Schaedelin SA, Stein K, Maleska Maceski A, Melie-Garcia L, Benkert P, Cagol A, Leber S, Galbusera R, Ruberte E, Hu W, Qureshi F, Orleth A, Demuth L, Willemse E, Heijnen I, Regeniter A, Derfuss TJ, Fischer-Barnicol B, Achtnichts L, Mueller S, Hoepner R, Lalive PH, Bridel C, D'Souza M, Pot C, Du Pasquier RA, Gobbi C, Zecca C, Wiendl H, Lieb JM, Lamers C, Kappos L, Trendelenburg M, Leppert D, Granziera C, Kuhle J, Lünemann JD; and the Swiss MS Cohort Study. Oechtering J, et al. Among authors: orleth a. Neurol Neuroimmunol Neuroinflamm. 2025 Mar;12(2):e200361. doi: 10.1212/NXI.0000000000200361. Epub 2025 Jan 3. Neurol Neuroimmunol Neuroinflamm. 2025. PMID: 39752618 Free PMC article.
Complement Activation Is Associated With Disease Severity in Multiple Sclerosis.
Oechtering J, Stein K, Schaedelin SA, Maceski AM, Orleth A, Meier S, Willemse E, Qureshi F, Heijnen I, Regeniter A, Derfuss T, Benkert P, D'Souza M, Limberg M, Fischer-Barnicol B, Achtnichts L, Mueller S, Salmen A, Lalive PH, Bridel C, Pot C, Du Pasquier RA, Gobbi C, Wiendl H, Granziera C, Kappos L, Trendelenburg M, Leppert D, Lunemann JD, Kuhle J; Swiss MS Cohort Study. Oechtering J, et al. Among authors: orleth a. Neurol Neuroimmunol Neuroinflamm. 2024 Mar;11(2):e200212. doi: 10.1212/NXI.0000000000200212. Epub 2024 Feb 14. Neurol Neuroimmunol Neuroinflamm. 2024. PMID: 38354323 Free PMC article.
The Swiss Multiple Sclerosis Cohort-Study (SMSC): A Prospective Swiss Wide Investigation of Key Phases in Disease Evolution and New Treatment Options.
Disanto G, Benkert P, Lorscheider J, Mueller S, Vehoff J, Zecca C, Ramseier S, Achtnichts L, Findling O, Nedeltchev K, Radue EW, Sprenger T, Stippich C, Derfuss T, Louvion JF, Kamm CP, Mattle HP, Lotter C, Du Pasquier R, Schluep M, Pot C, Lalive PH, Yaldizli Ö, Gobbi C, Kappos L, Kuhle J; SMSC Scientific Board. Disanto G, et al. PLoS One. 2016 Mar 31;11(3):e0152347. doi: 10.1371/journal.pone.0152347. eCollection 2016. PLoS One. 2016. PMID: 27032105 Free PMC article.
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